Seisyou Kou1, Luis Caballero2, Raluca Dulgheru3, Damien Voilliot4, Carla De Sousa5, George Kacharava6, George D Athanassopoulos7, Daniele Barone8, Monica Baroni9, Nuno Cardim10, Jose Juan Gomez De Diego11, Andreas Hagendorff12, Christine Henri3, Krasimira Hristova13, Teresa Lopez14, Julien Magne15, Gonzalo De La Morena2, Bogdan A Popescu16, Martin Penicka17, Tolga Ozyigit18, Jose David Rodrigo Carbonero19, Alessandro Salustri20, Nico Van De Veire21, Ralph Stephan Von Bardeleben22, Dragos Vinereanu23, Jens-Uwe Voigt24, Jose Luis Zamorano25, Erwan Donal26, Roberto M Lang27, Luigi P Badano28, Patrizio Lancellotti29. 1. Department of Cardiology, St Marianna University, School of Medicine, Kawasaki, Japan. 2. Unidad de Imagen Cardiaca, Servicio de Cardiologia, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain. 3. GIGA Cardiovascular Science, Heart Valve Clinic, Imaging Cardiology, University of Liège Hospital, Liege, Belgium. 4. Département de Cardiology, CHU de Brabois, Institut Lorrain du Coeur et des Vaisseaux Louis Mathieu, 54000 Nancy, France. 5. Cardiology Department, Centro Hospitalar São João/University of Porto Medical School, Porto, Portugal. 6. Echocardiography Laboratory of Adult Cardiology Department of the JOANN Medical Center, Tbilisi, Georgia. 7. Noninvasive Diagnostics Department, Onassis Cardiac Surgery Center, Athens, Greece. 8. Laboratory of Cardiovascular Ecography, Cardiology Department, S. Andrea Hospital, La Spezia, Italy. 9. Laboratorio Di Ecocardiografia Adulti, Fondazione Toscana 'G.Monasterio'-Ospedale Del Cuore, Massa, Italy. 10. Echocardiographylaboratory, Hospital da Luz, Lisbon, Portugal. 11. Unidad de Imagen Cardiovascular, ICV, Hospital Clinico San Carlos, Madrid, Spain. 12. Echokardiographie-Labore des Universitätsklinikums AöR, Department of Cardiology-Angiology, University of Leipzig, Leipzig, Germany. 13. Department of Noninvasive Functional Diagnostic and Imaging, University National Heart Hospital, Sofia, Bulgaria. 14. Cardiology Department, La Paz Hospital, Madrid, Spain. 15. CHU Limoges, Hôpital Dupuytren, Pôle Coeur-Poumon-Rein, Service Cardiologie, Limoges, France. 16. 'Carol Davila' University of Medicine and Pharmacy, Euroecolab, Institute of Cardiovascular Diseases, Bucharest, Romania. 17. Cardiovascular Center Aalst, OLV-Clinic, Aalst, Belgium. 18. VKV Amerikan Hastanesi, Kardiyoloji Bölümü, Istanbul, Turkey. 19. Laboratorio de Ecocardiografia Hospital de Cruces-Barakaldo, Barakaldo, Spain. 20. SheikhKhalifa Medical City, PO Box 51900, Abu Dhabi, UAE. 21. Echocardiography Unit, AZ Maria Middelares, Gent, Belgium. 22. Medical Department Cardiology, Universitätsmedizin of the Johannes Gutenberg-University Mainz, Germany. 23. Cardiovascular Research Unit, University and Emergency Hospital, University of Medicine and Pharmacy Carol Davila, Bucharest, Romania. 24. Echocardiography Laboratory, Department of Cardiovascular Diseases, University Hospital Gasthuisberg, Leuven, Belgium. 25. University Hospital Ramón y Cajal, Madrid, Spain. 26. CIC-IT U 804, CHU Rennes, Université Rennes 1, Service de Cardiologie, Chu Rennes, France. 27. Department of Medicine, University of Chicago Medical Center, Chicago, IL, USA. 28. Department of Cardiac, Thoracic and Vascular Sciences University of Padova, School of Medicine, Padova, Italy. 29. GIGA Cardiovascular Science, Heart Valve Clinic, Imaging Cardiology, University of Liège Hospital, Liege, Belgium plancellotti@chu.ulg.ac.be.
Abstract
AIMS: Availability of normative reference values for cardiac chamber quantitation is a prerequisite for accurate clinical application of echocardiography. In this study, we report normal reference ranges for cardiac chambers size obtained in a large group of healthy volunteers accounting for gender and age. Echocardiographic data were acquired using state-of-the-art cardiac ultrasound equipment following chamber quantitation protocols approved by the European Association of Cardiovascular Imaging. METHODS: A total of 734 (mean age: 45.8 ± 13.3 years) healthy volunteers (320 men and 414 women) were enrolled at 22 collaborating institutions of the Normal Reference Ranges for Echocardiography (NORRE) study. A comprehensive echocardiographic examination was performed on all subjects following pre-defined protocols. There were no gender differences in age or cholesterol levels. Compared with men, women had significantly smaller body surface areas, and lower blood pressure. Quality of echocardiographic data sets was good to excellent in the majority of patients. Upper and lower reference limits were higher in men than in women. The reference values varied with age. These age-related changes persisted for most parameters after normalization for the body surface area. CONCLUSION: The NORRE study provides useful two-dimensional echocardiographic reference ranges for cardiac chamber quantification. These data highlight the need for body size normalization that should be performed together with age-and gender-specific assessment for the most echocardiographic parameters. Published on behalf of the European Society of Cardiology. All rights reserved.
AIMS: Availability of normative reference values for cardiac chamber quantitation is a prerequisite for accurate clinical application of echocardiography. In this study, we report normal reference ranges for cardiac chambers size obtained in a large group of healthy volunteers accounting for gender and age. Echocardiographic data were acquired using state-of-the-art cardiac ultrasound equipment following chamber quantitation protocols approved by the European Association of Cardiovascular Imaging. METHODS: A total of 734 (mean age: 45.8 ± 13.3 years) healthy volunteers (320 men and 414 women) were enrolled at 22 collaborating institutions of the Normal Reference Ranges for Echocardiography (NORRE) study. A comprehensive echocardiographic examination was performed on all subjects following pre-defined protocols. There were no gender differences in age or cholesterol levels. Compared with men, women had significantly smaller body surface areas, and lower blood pressure. Quality of echocardiographic data sets was good to excellent in the majority of patients. Upper and lower reference limits were higher in men than in women. The reference values varied with age. These age-related changes persisted for most parameters after normalization for the body surface area. CONCLUSION: The NORRE study provides useful two-dimensional echocardiographic reference ranges for cardiac chamber quantification. These data highlight the need for body size normalization that should be performed together with age-and gender-specific assessment for the most echocardiographic parameters. Published on behalf of the European Society of Cardiology. All rights reserved.
Authors: Roberto M Lang; Michelle Bierig; Richard B Devereux; Frank A Flachskampf; Elyse Foster; Patricia A Pellikka; Michael H Picard; Mary J Roman; James Seward; Jack Shanewise; Scott Solomon; Kirk T Spencer; Martin St John Sutton; William Stewart Journal: Eur J Echocardiogr Date: 2006-02-02
Authors: Patrizio Lancellotti; Luigi P Badano; Roberto M Lang; Natela Akhaladze; George D Athanassopoulos; Daniele Barone; Monica Baroni; Nuno Cardim; Jose Juan Gomez de Diego; Genevieve Derumeaux; Raluca Dulgheru; Thor Edvardsen; Maurizio Galderisi; Alexandra Gonçalves; Gilbert Habib; Andreas Hagendorff; Krasimira Hristova; Seisyou Kou; Teresa Lopez; Julien Magne; Gonzalo de la Morena; Bogdan A Popescu; Martin Penicka; Tolga Rasit; Jose David Rodrigo Carbonero; Alessandro Salustri; Nico Van de Veire; Ralph Stephan von Bardeleben; Dragos Vinereanu; Jens-Uwe Voigt; Damien Voilliot; Jose Louis Zamorano; Erwan Donal; Gerald Maurer Journal: Eur Heart J Cardiovasc Imaging Date: 2013-01-31 Impact factor: 6.875
Authors: Jordan B Strom; Varsha K Tanguturi; Sherif F Nagueh; Allan L Klein; Warren J Manning Journal: J Am Soc Echocardiogr Date: 2019-09-25 Impact factor: 5.251