Literature DB >> 24434047

The role of molecular imaging in modern drug development.

Lídia Cunha1, Krisztián Szigeti2, Domokos Mathé3, Luís F Metello4.   

Abstract

Drug development represents a highly complex, inefficient and costly process. Over the past decade, the widespread use of nuclear imaging, owing to its functional and molecular nature, has proven to be a determinant in improving the efficiency in selecting the candidate drugs that should either be abandoned or moved forward into clinical trials. This helps not only with the development of safer and effective drugs but also with the shortening of time-to-market. The modern concept and future trends concerning molecular imaging will assumedly be hybrid or multimodality imaging, including combinations between high sensitivity and functional (molecular) modalities with high spatial resolution and morphological techniques.
Copyright © 2014 Elsevier Ltd. All rights reserved.

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Year:  2014        PMID: 24434047     DOI: 10.1016/j.drudis.2014.01.003

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN: 1359-6446            Impact factor:   7.851


  15 in total

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