Literature DB >> 2443156

Wound healing: the effect of macrophage and tumour derived angiogenesis factors on skin graft vascularization.

F Arnold1, D West, S Kumar.   

Abstract

Angiogenic factors prepared from rat Walker 256 mammary carcinoma, (TAF) and activated mouse peritoneal macrophages (MAF), were tested for their ability to stimulate vascularization during healing. They were applied to one of a pair of bilaterally symmetrical, autologous, isotopic, full thickness skin grafts in mice. Blood flow to treated and untreated graft pairs was compared by their uptake of injected 86Rb Cl, at 3 and 7 days after grafting. No difference was detected after treatment with either agent. We conclude that while angiogenic factors are important in vascularization during healing, this normally occurs at a near maximal rate and cannot be further enhanced.

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Year:  1987        PMID: 2443156      PMCID: PMC2013150     

Source DB:  PubMed          Journal:  Br J Exp Pathol        ISSN: 0007-1021


  14 in total

1.  Stimulation of granulation tissue growth by tissue extracts. Study in intramuscular wounds in rabbits.

Authors:  R H EDWARDS; S S SARMENTA; G M HASS
Journal:  Arch Pathol       Date:  1960-03

2.  Activated macrophages induce vascular proliferation.

Authors:  P J Polverini; P S Cotran; M A Gimbrone; E R Unanue
Journal:  Nature       Date:  1977-10-27       Impact factor: 49.962

3.  The amnion in surgery, past and present.

Authors:  J D Trelford; M Trelford-Sauder
Journal:  Am J Obstet Gynecol       Date:  1979-08-01       Impact factor: 8.661

4.  Angiogenesis induced by degradation products of hyaluronic acid.

Authors:  D C West; I N Hampson; F Arnold; S Kumar
Journal:  Science       Date:  1985-06-14       Impact factor: 47.728

5.  Isolation of a nonmitogenic angiogenesis factor from wound fluid.

Authors:  M J Banda; D R Knighton; T K Hunt; Z Werb
Journal:  Proc Natl Acad Sci U S A       Date:  1982-12       Impact factor: 11.205

6.  The proliferative response in vitro of vascular endothelial and smooth muscle cells exposed to wound fluids and macrophages.

Authors:  G B Greenburg; T K Hunt
Journal:  J Cell Physiol       Date:  1978-12       Impact factor: 6.384

7.  Angiogenic activity in human wound fluid.

Authors:  F Arnold; D C West; P F Schofield; S Kumar
Journal:  Int J Microcirc Clin Exp       Date:  1987

8.  Tumour angiogenesis factor (TAF) and its neutralisation by a xenogeneic antiserum.

Authors:  P Phillips; S Kumar
Journal:  Int J Cancer       Date:  1979-01-15       Impact factor: 7.396

9.  Eye-derived growth factor isolated from bovine retina and used for epidermal wound healing in vivo.

Authors:  A Y Fourtanier; J Courty; E Muller; Y Courtois; M Prunieras; D Barritault
Journal:  J Invest Dermatol       Date:  1986-07       Impact factor: 8.551

10.  Effect of tumour angiogenesis factors on the membrane of capillary and aortic endothelial cells: an e.s.r. spin-label study.

Authors:  N J Dodd; S Kumar
Journal:  J Cell Sci       Date:  1984-06       Impact factor: 5.285

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Journal:  Cell       Date:  2003-03-07       Impact factor: 41.582

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Journal:  Infect Immun       Date:  2017-07-19       Impact factor: 3.441

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Authors:  Sara J Wezensky; Robert A Cramer
Journal:  Med Mycol       Date:  2010-06-21       Impact factor: 4.076

9.  Vitamin A depletion causes oxidative stress, mitochondrial dysfunction, and PARP-1-dependent energy deprivation.

Authors:  Haw-Jyh Chiu; Donald A Fischman; Ulrich Hammerling
Journal:  FASEB J       Date:  2008-08-01       Impact factor: 5.191

10.  Copper transport into the secretory pathway is regulated by oxygen in macrophages.

Authors:  Carine White; Taiho Kambe; Yan G Fulcher; Sherri W Sachdev; Ashley I Bush; Kevin Fritsche; Jaekwon Lee; Thomas P Quinn; Michael J Petris
Journal:  J Cell Sci       Date:  2009-04-07       Impact factor: 5.285

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