Literature DB >> 2408340

Angiogenesis induced by degradation products of hyaluronic acid.

D C West, I N Hampson, F Arnold, S Kumar.   

Abstract

Partial degradation products of sodium hyaluronate produced by the action of testicular hyaluronidase induced an angiogenic response (formation of new blood vessels) on the chick chorioallantoic membrane. Neither macromolecular hyaluronate nor exhaustively digested material had any angiogenic potential. Fractionation of the digestion products established that the activity was restricted to hyaluronate fragments between 4 and 25 disaccharides in length.

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Year:  1985        PMID： 2408340     DOI： 10.1126/science.2408340

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  219 in total

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