Literature DB >> 24381746

Assessment of health status in elderly patients with cancer.

Joanna Kaźmierska1.   

Abstract

BACKGROUND: Health status assessment of senior adults is one of the most important aspects of a treatment decision making process. A group of elderly cancer patients is very heterogeneous according to the health status - some of them are fit enough for aggressive treatment, but others are frail and vulnerable. Treatment for the latter group has to be adapted and carefully monitored. AIM: To review and analyze relevant literature on the usage and optimization of Comprehensive Geriatric Assessment (CGA).
MATERIALS AND METHODS: Medline search of studies published between 2000 and 2011, containing key words: Comprehensive Geriatric Assessment, aging, cancer in senior adults, frailty.
RESULTS: To recognize and address individual needs of senior adults, a special holistic approach has been developed - comprehensive geriatric assessment (CGA). This tool is a gold standard in gerontooncology, recommended by International Society of Geriatric Oncology. CGA evaluates all important health domains, from physiology to social and economical problems, using sets of different tests. Assessment has to be performed by a trained team, including a physician, nurse and social worker. CGA has been clinically validated in many studies, but it is still not clear whether CGA improves the outcome of treatment of the elderly with cancer.
CONCLUSIONS: Complexity and multidimensionality of CGA pose a logistic challenge for everyday clinical practice. Special senior programs, which could be developed inside comprehensive cancer center, focusing attention on seniors' problems and needs seem to be a way forward for geriatric oncology.

Entities:  

Keywords:  Aging; Comprehensive geriatric assessment; Elderly; Frailty

Year:  2012        PMID: 24381746      PMCID: PMC3863187          DOI: 10.1016/j.rpor.2012.07.007

Source DB:  PubMed          Journal:  Rep Pract Oncol Radiother        ISSN: 1507-1367


  38 in total

Review 1.  Use of comprehensive geriatric assessment in older cancer patients: recommendations from the task force on CGA of the International Society of Geriatric Oncology (SIOG).

Authors:  Martine Extermann; Matti Aapro; Roberto Bernabei; Harvey Jay Cohen; Jean-Pierre Droz; Stuart Lichtman; Vincent Mor; Silvio Monfardini; Lazzaro Repetto; Liv Sørbye; Eva Topinkova
Journal:  Crit Rev Oncol Hematol       Date:  2005-09       Impact factor: 6.312

2.  A summated score for the medication appropriateness index: development and assessment of clinimetric properties including content validity.

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Journal:  J Clin Epidemiol       Date:  1994-08       Impact factor: 6.437

3.  Frailty in older adults: evidence for a phenotype.

Authors:  L P Fried; C M Tangen; J Walston; A B Newman; C Hirsch; J Gottdiener; T Seeman; R Tracy; W J Kop; G Burke; M A McBurnie
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2001-03       Impact factor: 6.053

Review 4.  Overview of the MNA--Its history and challenges.

Authors:  B Vellas; H Villars; G Abellan; M E Soto; Y Rolland; Y Guigoz; J E Morley; W Chumlea; A Salva; L Z Rubenstein; P Garry
Journal:  J Nutr Health Aging       Date:  2006 Nov-Dec       Impact factor: 4.075

5.  Relative survival in elderly European cancer patients: evidence for health care inequalities. The EUROCARE Working Group.

Authors:  M Vercelli; R Capocaccia; A Quaglia; C Casella; A Puppo; J W Coebergh
Journal:  Crit Rev Oncol Hematol       Date:  2000-09       Impact factor: 6.312

6.  A specialized home care intervention improves survival among older post-surgical cancer patients.

Authors:  R McCorkle; N E Strumpf; I F Nuamah; D C Adler; M E Cooley; C Jepson; E J Lusk; M Torosian
Journal:  J Am Geriatr Soc       Date:  2000-12       Impact factor: 5.562

7.  Serum albumin level and physical disability as predictors of mortality in older persons.

Authors:  M C Corti; J M Guralnik; M E Salive; J D Sorkin
Journal:  JAMA       Date:  1994-10-05       Impact factor: 56.272

8.  Validation of a combined comorbidity index.

Authors:  M Charlson; T P Szatrowski; J Peterson; J Gold
Journal:  J Clin Epidemiol       Date:  1994-11       Impact factor: 6.437

9.  Usefulness of frailty markers in the assessment of the health and functional status of older cancer patients referred for chemotherapy: a pilot study.

Authors:  Frederique Retornaz; Johanne Monette; Gerald Batist; Michèle Monette; Nadia Sourial; David Small; Stephen Caplan; Doreen Wan-Chow-Wah; Martine T E Puts; Howard Bergman
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2008-05       Impact factor: 6.053

10.  Prognostic effect of weight loss prior to chemotherapy in cancer patients. Eastern Cooperative Oncology Group.

Authors:  W D Dewys; C Begg; P T Lavin; P R Band; J M Bennett; J R Bertino; M H Cohen; H O Douglass; P F Engstrom; E Z Ezdinli; J Horton; G J Johnson; C G Moertel; M M Oken; C Perlia; C Rosenbaum; M N Silverstein; R T Skeel; R W Sponzo; D C Tormey
Journal:  Am J Med       Date:  1980-10       Impact factor: 4.965

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  3 in total

1.  Cancer in the elderly.

Authors:  Jiří Petera; Ladislav Dušek
Journal:  Rep Pract Oncol Radiother       Date:  2012-12-23

Review 2.  Disease specific substrates in cancer cachexia - Reality and anticipation.

Authors:  Zdeněk Zadák; Alena Tichá; Radomír Hyšpler
Journal:  Rep Pract Oncol Radiother       Date:  2012-12-05

3.  Geriatric assessment-identified deficits in older cancer patients with normal performance status.

Authors:  Trevor A Jolly; Allison M Deal; Kirsten A Nyrop; Grant R Williams; Mackenzi Pergolotti; William A Wood; Shani M Alston; Brittaney-Belle E Gordon; Samara A Dixon; Susan G Moore; W Chris Taylor; Michael Messino; Hyman B Muss
Journal:  Oncologist       Date:  2015-03-12
  3 in total

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