Literature DB >> 2438130

A malaria protein exported into a new compartment within the host erythrocyte.

D Simmons, G Woollett, M Bergin-Cartwright, D Kay, J Scaife.   

Abstract

A Plasmodium falciparum protein which is exported into a new compartment in the host erythrocyte has been located. This protein, exp-1, has a variable region recognized by a monoclonal antibody. Naturally occurring mutants of this region have been characterized. All mutants studied so far have the same A----G transition abolishing the target for the antibody. The exp-1 gene has a complex structure containing two introns. It is highly conserved in five independent, genetically defined parasite lines, suggesting that exp-1 has an important function. We discuss the possible role of exp-1 in P. falciparum infections.

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Year:  1987        PMID： 2438130      PMCID： PMC553420          DOI： 10.1002/j.1460-2075.1987.tb04779.x

Source DB:  PubMed          Journal:  EMBO J        ISSN： 0261-4189            Impact factor:   11.598


  38 in total

1.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

Review 2.  Biochemistry of Plasmodium (malarial parasites).

Authors:  I W Sherman
Journal:  Microbiol Rev       Date:  1979-12

3.  Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

Authors:  H Towbin; T Staehelin; J Gordon
Journal:  Proc Natl Acad Sci U S A       Date:  1979-09       Impact factor: 11.205

4.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

Review 5.  Alterations in the surface membrane of red blood cells during malaria.

Authors:  R J Howard
Journal:  Immunol Rev       Date:  1982       Impact factor: 12.988

6.  Cloning of naturally occurring mixed infections of malaria parasites.

Authors:  V Rosario
Journal:  Science       Date:  1981-05-29       Impact factor: 47.728

7.  Resistance of ten Thai isolates of Plasmodium falciparum to chloroquine and pyrimethamine by in vitro tests.

Authors:  S Thaithong; G H Beale
Journal:  Trans R Soc Trop Med Hyg       Date:  1981       Impact factor: 2.184

8.  Human malaria parasites in continuous culture.

Authors:  W Trager; J B Jensen
Journal:  Science       Date:  1976-08-20       Impact factor: 47.728

9.  A procedure for the harvesting of mammalian plasmodia.

Authors:  A Zuckerman; D Spira; J Hamburger
Journal:  Bull World Health Organ       Date:  1967       Impact factor: 9.408

10.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205
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  41 in total

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Authors:  E S Son; T S Kim; H W Nam
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2.  Longitudinal study of Plasmodium falciparum polymorphic antigens in a malaria-endemic population.

Authors:  D J Conway; B M Greenwood; J S McBride
Journal:  Infect Immun       Date:  1992-03       Impact factor: 3.441

3.  Expression of merozoite surface protein markers by Plasmodium falciparum-infected erythrocytes in peripheral blood and tissues of children with fatal malaria.

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Journal:  Infect Immun       Date:  2006-11-21       Impact factor: 3.441

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Authors:  M F Wiser; H N Lanners
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5.  Protein targeting to the parasitophorous vacuole membrane of Plasmodium falciparum.

Authors:  Saliha Eksi; Kim C Williamson
Journal:  Eukaryot Cell       Date:  2011-04-15

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Authors:  Tobias Spielmann; David J P Fergusen; Hans-Peter Beck
Journal:  Mol Biol Cell       Date:  2003-04       Impact factor: 4.138

7.  Supergenomic network compression and the discovery of EXP1 as a glutathione transferase inhibited by artesunate.

Authors:  Andreas Martin Lisewski; Joel P Quiros; Caroline L Ng; Anbu Karani Adikesavan; Kazutoyo Miura; Nagireddy Putluri; Richard T Eastman; Daniel Scanfeld; Sam J Regenbogen; Lindsey Altenhofen; Manuel Llinás; Arun Sreekumar; Carole Long; David A Fidock; Olivier Lichtarge
Journal:  Cell       Date:  2014-08-14       Impact factor: 41.582

8.  Immune response against the exp-1 protein of Plasmodium falciparum results in antibodies that cross-react with human T-cell lymphotropic virus type 1 proteins.

Authors:  K R Porter; J Aguiar; A Richards; B Sandjaya; H Ignatias; H Hadiputranto; R G Ridley; B Takacs; F S Wignall; S L Hoffman; C G Hayes
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9.  A key role for lipoic acid synthesis during Plasmodium liver stage development.

Authors:  Brie Falkard; T R Santha Kumar; Leonie-Sophie Hecht; Krista A Matthews; Philipp P Henrich; Sonia Gulati; Rebecca E Lewis; Micah J Manary; Elizabeth A Winzeler; Photini Sinnis; Sean T Prigge; Volker Heussler; Christina Deschermeier; David Fidock
Journal:  Cell Microbiol       Date:  2013-04-05       Impact factor: 3.715

10.  LISP1 is important for the egress of Plasmodium berghei parasites from liver cells.

Authors:  Tomoko Ishino; Bertrand Boisson; Yuki Orito; Céline Lacroix; Emmanuel Bischoff; Céline Loussert; Chris Janse; Robert Ménard; Masao Yuda; Patricia Baldacci
Journal:  Cell Microbiol       Date:  2009-05-06       Impact factor: 3.715
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