Literature DB >> 7029802

Resistance of ten Thai isolates of Plasmodium falciparum to chloroquine and pyrimethamine by in vitro tests.

S Thaithong, G H Beale.   

Abstract

In vitro drug resistance tests of ten isolates of Plasmodium falciparum from three different collection points in Central Thailand have been carried out, and the results compared with those of similar tests with a drug-sensitive West African isolate. Judged by concentration of drug tolerated, the Thai isolates appeared to be about 10 times as resistant to chloroquine, and usually about 10(5) times as resistant to pyrimethamine, as the African isolate. A little variation amongst the Thai isolates was detected.

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Year:  1981        PMID: 7029802     DOI: 10.1016/0035-9203(81)90333-3

Source DB:  PubMed          Journal:  Trans R Soc Trop Med Hyg        ISSN: 0035-9203            Impact factor:   2.184


  38 in total

1.  Rhoptry-associated protein 1-binding monoclonal antibody raised against a heterologous peptide sequence inhibits Plasmodium falciparum growth in vitro.

Authors:  R Moreno; F Pöltl-Frank; D Stüber; H Matile; M Mutz; N A Weiss; G Pluschke
Journal:  Infect Immun       Date:  2001-04       Impact factor: 3.441

2.  Antimalarial 9-anilinoacridine compounds directed at hematin.

Authors:  Saranya Auparakkitanon; Wilai Noonpakdee; Raymond K Ralph; William A Denny; Prapon Wilairat
Journal:  Antimicrob Agents Chemother       Date:  2003-12       Impact factor: 5.191

3.  Plasmodium falciparum parasites expressing pregnancy-specific variant surface antigens adhere strongly to the choriocarcinoma cell line BeWo.

Authors:  Rikke N Haase; Rosette Megnekou; Maja Lundquist; Michael F Ofori; Lars Hviid; Trine Staalsoe
Journal:  Infect Immun       Date:  2006-05       Impact factor: 3.441

4.  Targeting of hematin by the antimalarial pyronaridine.

Authors:  Saranya Auparakkitanon; Soebsakul Chapoomram; Kannika Kuaha; Thamrong Chirachariyavej; Prapon Wilairat
Journal:  Antimicrob Agents Chemother       Date:  2006-06       Impact factor: 5.191

5.  New quinoline di-Mannich base compounds with greater antimalarial activity than chloroquine, amodiaquine, or pyronaridine.

Authors:  B M Kotecka; G B Barlin; M D Edstein; K H Rieckmann
Journal:  Antimicrob Agents Chemother       Date:  1997-06       Impact factor: 5.191

6.  The accumulation of lactic acid and its influence on the growth of Plasmodium falciparum in synchronized cultures.

Authors:  J W Zolg; A J Macleod; J G Scaife; R L Beaudoin
Journal:  In Vitro       Date:  1984-03

7.  Multiple Novel Mutations in Plasmodium falciparum Chloroquine Resistance Transporter Gene during Implementation of Artemisinin Combination Therapy in Thailand.

Authors:  Pattakorn Buppan; Sunee Seethamchai; Napaporn Kuamsab; Pongchai Harnyuttanakorn; Chaturong Putaporntip; Somchai Jongwutiwes
Journal:  Am J Trop Med Hyg       Date:  2018-10       Impact factor: 2.345

8.  Removal of heterologous sequences from Plasmodium falciparum mutants using FLPe-recombinase.

Authors:  Ben C L van Schaijk; Martijn W Vos; Chris J Janse; Robert W Sauerwein; Shahid M Khan
Journal:  PLoS One       Date:  2010-11-30       Impact factor: 3.240

9.  The gene encoding DNA polymerase alpha from Plasmodium falciparum.

Authors:  J H White; B J Kilbey; E de Vries; M Goman; P Alano; S Cheesman; S McAleese; R G Ridley
Journal:  Nucleic Acids Res       Date:  1993-08-11       Impact factor: 16.971

10.  Comparative transcriptional and genomic analysis of Plasmodium falciparum field isolates.

Authors:  Margaret J Mackinnon; Jinguang Li; Sachel Mok; Moses M Kortok; Kevin Marsh; Peter R Preiser; Zbynek Bozdech
Journal:  PLoS Pathog       Date:  2009-10-30       Impact factor: 6.823

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