Literature DB >> 2437471

Effects of ketamine on the cholecystokinin, somatostatin, substance P, and thyrotropin releasing hormone in discrete regions of rat brain.

K Pongdhana, N Ogawa, Y Hirose, T Ono, F Kosaka, A Mori.   

Abstract

Intraperitoneal injection of ketamine (100 mg/kg body weight) significantly reduces the levels of cholecystokinin (CCK), somatostatin (SRIF), and substance P (SP)-like immunoreactivity in various regions of rat brain. No significant change in thyrotropin releasing hormone (TRH)-like immunoreactivity was observed. Neuropeptide systems may be involved in the neuropharmacologic effects of ketamine.

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Year:  1987        PMID： 2437471     DOI： 10.1007/bf00971367

Source DB:  PubMed          Journal:  Neurochem Res        ISSN： 0364-3190            Impact factor:   3.996


  30 in total

1.  On the neuropharmacology of thyrotropin releasing hormone (TRH).

Authors:  G G Yarbrough
Journal:  Prog Neurobiol       Date:  1979       Impact factor: 11.685

2.  Properties of soluble somatostatin-binding protein.

Authors:  N Ogawa; T Thompson; H G Friesen; J B Martin; P Brazeau
Journal:  Biochem J       Date:  1977-08-01       Impact factor: 3.857

3.  The interaction of ketamine with the opiate receptor.

Authors:  D J Smith; G M Pekoe; L L Martin; B Coalgate
Journal:  Life Sci       Date:  1980-03-10       Impact factor: 5.037

4.  Rapid depletion and restoration of striatal met-enkephalin after ketamine.

Authors:  W Fratta; Z Rossetti; G L Gessa
Journal:  Life Sci       Date:  1981-07-06       Impact factor: 5.037

5.  Lack of antagonism by naloxone of the analgesic and locomotor stimulant actions of ketamine.

Authors:  J N Wiley; D A Downs
Journal:  Life Sci       Date:  1982-09-13       Impact factor: 5.037

6.  Ketamine hydrochloride in severe bronchospasm.

Authors:  M M Fischer
Journal:  Anaesthesia       Date:  1977-09       Impact factor: 6.955

7.  E.E.G. and multiple unit activity during ketamine and barbiturate anaesthesia.

Authors:  V Tamásy; L Korányi; M Tekeres
Journal:  Br J Anaesth       Date:  1975-12       Impact factor: 9.166

8.  The regional distribution of somatostatin, substance P and neurotensin in human brain.

Authors:  P E Cooper; M H Fernstrom; O P Rorstad; S E Leeman; J B Martin
Journal:  Brain Res       Date:  1981-08-10       Impact factor: 3.252

9.  Interactions of cholinesterase inhibitors and glucocorticoids with ketamine and pentobarbitone-induced general anaesthesia in the rat: possible effects on central cholinergic activity.

Authors:  R S Leeuwin; J K van der Wal; W Spanjer
Journal:  Br J Pharmacol       Date:  1984-06       Impact factor: 8.739

10.  Acetylcholine concentrations and turnover in rat brain structures during anesthesia with halothane, enflurane, and ketamine.

Authors:  S H Ngai; D L Cheney; A D Finck
Journal:  Anesthesiology       Date:  1978-01       Impact factor: 7.892
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  4 in total

1.  Acute reduction of brain substance P induced by nicotine.

Authors:  N E Naftchi; H Maker; E Lapin; J Sleis; A Lajtha; S Leeman
Journal:  Neurochem Res       Date:  1988-04       Impact factor: 3.996

2.  Short-Term Administration of Common Anesthetics Does Not Dramatically Change the Endogenous Peptide Profile in the Rat Pituitary.

Authors:  Somayeh Mousavi; Haowen Qiu; Frazer I Heinis; Md Shadman Ridwan Abid; Matthew T Andrews; James W Checco
Journal:  ACS Chem Neurosci       Date:  2022-09-20       Impact factor: 5.780

3.  Regional changes in neuropeptide levels after 5,7-dihydroxytryptamine-induced serotonin depletion in the rat brain.

Authors:  Y Kondo; N Ogawa; M Asanuma; H Hirata; K Tanaka; Y Kawada; A Mori
Journal:  J Neural Transm Gen Sect       Date:  1993

4.  Loss of N-methyl-D-aspartate (NMDA) receptor binding in rat hippocampal areas at the chronic stage after transient forebrain ischemia: histological and NMDA receptor binding studies.

Authors:  N Ogawa; K Haba; K Mizukawa; M Asanuma; H Hirata; A Mori
Journal:  Neurochem Res       Date:  1991-05       Impact factor: 3.996
  4 in total

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