Mohammed Alhumaidi1, Adnan Agha2, Mohamed Dewish3. 1. King Khalid University, Department of Medicine, Abha, Saudi Arabia. 2. Blackpool Victoria Hospital, SPR Endocrinology & Diabetes, Blackpool, UK. 3. Consultant Endocrinology, Riyadh Military Hospital Riyadh Military Hospital, Riyadh, Saudi Arabia.
Abstract
INTRODUCTION: Type-2 diabetes mellitus and Vitamin D deficiency are both common in Saudi Arabian population. New roles of vitamin D have emerged recently especially in the prevention of cardiovascular disease, cancer and insulin resistance. OBJECTIVE: To estimate 25-OH vitamin D deficiency in patients with type-2 diabetes mellitus in comparison to normal age-matched non-diabetic control population. METHODS: A Randomized Case-Control study was done in three tertiary care hospitals in Southern Region, Saudi Arabia from June 2010 to June 2012 and 345 patients were selected; 172 in the diabetic group and 173 in the non-diabetic group. Biochemical workup and 25-OH vitamin D levels were done. RESULTS: The mean serum 25-OH vitamin D levels in the diabetic group were 15.7 + 7.5 ng/mL as compared healthy non-diabetic group having 11.1 + 5.9 ng/mL and a total of 340 patients (98.5%) from both groups were found to be deficient in 25-OH vitamin D which is the highest reported so far in Saudi Arabia. CONCLUSION: The population in our study was generally deficient in 25-OH vitamin D irrespective of diabetes mellitus indicating a greater need for vitamin D supplementation.
INTRODUCTION:Type-2 diabetes mellitus and Vitamin Ddeficiency are both common in Saudi Arabian population. New roles of vitamin D have emerged recently especially in the prevention of cardiovascular disease, cancer and insulin resistance. OBJECTIVE: To estimate 25-OH vitamin Ddeficiency in patients with type-2 diabetes mellitus in comparison to normal age-matched non-diabetic control population. METHODS: A Randomized Case-Control study was done in three tertiary care hospitals in Southern Region, Saudi Arabia from June 2010 to June 2012 and 345 patients were selected; 172 in the diabetic group and 173 in the non-diabetic group. Biochemical workup and 25-OH vitamin D levels were done. RESULTS: The mean serum 25-OH vitamin D levels in the diabetic group were 15.7 + 7.5 ng/mL as compared healthy non-diabetic group having 11.1 + 5.9 ng/mL and a total of 340 patients (98.5%) from both groups were found to be deficient in 25-OH vitamin D which is the highest reported so far in Saudi Arabia. CONCLUSION: The population in our study was generally deficient in 25-OH vitamin D irrespective of diabetes mellitus indicating a greater need for vitamin D supplementation.
Entities:
Keywords:
Saudi Arabia; diabetes mellitus; sunlight exposure; vitamin D deficiency
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