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Literature DB >> 24361313

Could silencing IRF5 improve healing of a myocardial infarct through the reprogramming of the macrophage population?

Jennifer L Hall¹, Li-Na Wei².

Abstract

Entities: Chemical Disease Gene Species

Keywords: IRF5; M1 to M2 transition; macrophage; myocardial infarction

Mesh：

Substances：

Year: 2013 PMID： 24361313 PMCID： PMC5124366 DOI： 10.1016/j.jacc.2013.11.024

Source DB: PubMed Journal: J Am Coll Cardiol ISSN： 0735-1097 Impact factor: 24.094

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8 in total

Review 1. Transcriptional regulation of macrophage polarization: enabling diversity with identity.

Authors: Toby Lawrence; Gioacchino Natoli
Journal: Nat Rev Immunol Date: 2011-10-25 Impact factor: 53.106

2. IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses.

Authors: Thomas Krausgruber; Katrina Blazek; Tim Smallie; Saba Alzabin; Helen Lockstone; Natasha Sahgal; Tracy Hussell; Marc Feldmann; Irina A Udalova
Journal: Nat Immunol Date: 2011-01-16 Impact factor: 25.606

3. Coronary atherosclerosis is associated with macrophage polarization in epicardial adipose tissue.

Authors: Yoichiro Hirata; Minoru Tabata; Hirotsugu Kurobe; Tatsuo Motoki; Masashi Akaike; Chika Nishio; Mayuko Higashida; Hiroaki Mikasa; Yutaka Nakaya; Shuichiro Takanashi; Takashi Igarashi; Tetsuya Kitagawa; Masataka Sata
Journal: J Am Coll Cardiol Date: 2011-07-12 Impact factor: 24.094

Review 4. Transcriptional control of macrophage polarization.

Authors: Derin Tugal; Xudong Liao; Mukesh K Jain
Journal: Arterioscler Thromb Vasc Biol Date: 2013-05-02 Impact factor: 8.311

5. Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors.

Authors: Akinori Takaoka; Hideyuki Yanai; Seiji Kondo; Gordon Duncan; Hideo Negishi; Tatsuaki Mizutani; Shin-Ichi Kano; Kenya Honda; Yusuke Ohba; Tak W Mak; Tadatsugu Taniguchi
Journal: Nature Date: 2005-01-23 Impact factor: 49.962

Review 6. Monocyte and macrophage heterogeneity in the heart.

Authors: Matthias Nahrendorf; Filip K Swirski
Journal: Circ Res Date: 2013-06-07 Impact factor: 17.367

7. Macrophage subpopulations are essential for infarct repair with and without stem cell therapy.

Authors: Tamar Ben-Mordechai; Radka Holbova; Natalie Landa-Rouben; Tamar Harel-Adar; Micha S Feinberg; Ihab Abd Elrahman; Galia Blum; Fred H Epstein; Zmira Silman; Smadar Cohen; Jonathan Leor
Journal: J Am Coll Cardiol Date: 2013-08-21 Impact factor: 24.094

8. NF-κB-mediated degradation of the coactivator RIP140 regulates inflammatory responses and contributes to endotoxin tolerance.

Authors: Ping-Chih Ho; Yao-Chen Tsui; Xudong Feng; David R Greaves; Li-Na Wei
Journal: Nat Immunol Date: 2012-03-04 Impact factor: 25.606

8 in total

5 in total

Could silencing IRF5 improve healing of a myocardial infarct through the reprogramming of the macrophage population?

Review 1. Transcriptional regulation of macrophage polarization: enabling diversity with identity.

2. IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses.

3. Coronary atherosclerosis is associated with macrophage polarization in epicardial adipose tissue.

Review 4. Transcriptional control of macrophage polarization.

5. Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors.

Review 6. Monocyte and macrophage heterogeneity in the heart.

7. Macrophage subpopulations are essential for infarct repair with and without stem cell therapy.

8. NF-κB-mediated degradation of the coactivator RIP140 regulates inflammatory responses and contributes to endotoxin tolerance.

Review 1. Microglial and macrophage polarization—new prospects for brain repair.

Review 2. Current Development of Nano-Drug Delivery to Target Macrophages.

Review 3. Therapeutic Targeting of IRFs: Pathway-Dependence or Structure-Based?

Review 4. Ca²⁺ Flux: Searching for a Role in Efferocytosis of Apoptotic Cells in Atherosclerosis.

5. Immunogene therapy with fusogenic nanoparticles modulates macrophage response to Staphylococcus aureus.

Could silencing IRF5 improve healing of a myocardial infarct through the reprogramming of the macrophage population?

Review 1. Transcriptional regulation of macrophage polarization: enabling diversity with identity.

2. IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses.

3. Coronary atherosclerosis is associated with macrophage polarization in epicardial adipose tissue.

Review 4. Transcriptional control of macrophage polarization.

5. Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors.

Review 6. Monocyte and macrophage heterogeneity in the heart.

7. Macrophage subpopulations are essential for infarct repair with and without stem cell therapy.

8. NF-κB-mediated degradation of the coactivator RIP140 regulates inflammatory responses and contributes to endotoxin tolerance.

Review 1. Microglial and macrophage polarization—new prospects for brain repair.

Review 2. Current Development of Nano-Drug Delivery to Target Macrophages.

Review 3. Therapeutic Targeting of IRFs: Pathway-Dependence or Structure-Based?

Review 4. Ca2+ Flux: Searching for a Role in Efferocytosis of Apoptotic Cells in Atherosclerosis.

5. Immunogene therapy with fusogenic nanoparticles modulates macrophage response to Staphylococcus aureus.

Review 4. Ca²⁺ Flux: Searching for a Role in Efferocytosis of Apoptotic Cells in Atherosclerosis.