Literature DB >> 23743228

Monocyte and macrophage heterogeneity in the heart.

Matthias Nahrendorf1, Filip K Swirski.   

Abstract

Monocytes and macrophages are innate immune cells that reside and accumulate in the healthy and injured heart. The cells and their subsets pursue distinct functions in steady-state and disease, and their tenure may range between hours and months. Some subsets are highly inflammatory, whereas others support tissue repair. This review discusses current concepts of lineage relationships and crosstalk of systems, highlights open questions, and describes tools for studying monocyte and macrophage subsets in the murine and human heart.

Entities:  

Keywords:  healing; heart failure; macrophages; monocytes; myocardial infarction

Mesh：

Substances：

Year:  2013        PMID： 23743228      PMCID： PMC3753681          DOI： 10.1161/CIRCRESAHA.113.300890

Source DB:  PubMed          Journal:  Circ Res        ISSN： 0009-7330            Impact factor:   17.367


  95 in total

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Review 5.  Obesity, Hypertension, and Cardiac Dysfunction: Novel Roles of Immunometabolism in Macrophage Activation and Inflammation.

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Review 6.  Cellular immunity and cardiac remodeling after myocardial infarction: role of neutrophils, monocytes, and macrophages.

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Review 7.  Mononuclear phagocyte subpopulations in the mouse kidney.

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Journal:  Circ Cardiovasc Imaging       Date:  2013-10-04       Impact factor: 7.792
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