Literature DB >> 24343032

[Chronic wounds and bacteria. Clinical relevance, detection and therapy].

J Dissemond1.   

Abstract

The importance of bacteria in the treatment of patients with chronic wounds has been a focus of attention in recent years. A bacteriological swab taken from the wound in a Essen rotary technique is usually adequate for the diagnosis. The current detection rate of bacteria in patients with chronic leg ulcers in Germany is about 50 % for Staphylococcus aureus, 30 % for Pseudomonas aeruginosa and Enterobacteriaceae and approximately 10 % for MRSA. Most of these patients have a clinically unimportant bacterial colonization, so that systemic administration of antibiotics usually is not required. For wound cleansing only sterile solutions such as Ringer's or physiological saline solution should be used. If tap water is used, then the use of sterile filters is strongly recommended. In patients with increased risk of infection, a critical colonization or local signs of infection, modern wound antiseptics using polyhexanide or octenidine are available. The use of systemic antibiotics should be strictly limited to patients with systemic signs of infections.

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Year:  2014        PMID: 24343032     DOI: 10.1007/s00105-013-2635-9

Source DB:  PubMed          Journal:  Hautarzt        ISSN: 0017-8470            Impact factor:   0.751


  19 in total

1.  Evaluation of the Essen Rotary as a new technique for bacterial swabs: results of a prospective controlled clinical investigation in 50 patients with chronic leg ulcers.

Authors:  Philipp Al Ghazal; Andreas Körber; Joachim Klode; Ernst N Schmid; Jan Buer; Joachim Dissemond
Journal:  Int Wound J       Date:  2012-07-09       Impact factor: 3.315

2.  No need for biopsies: comparison of three sample techniques for wound microbiota determination.

Authors:  Kristine Gjødsbøl; Mette E Skindersoe; Jens Jørgen Christensen; Tonny Karlsmark; Bo Jørgensen; Anders Mørup Jensen; Bjarke M Klein; Michael K Sonnested; Karen A Krogfelt
Journal:  Int Wound J       Date:  2011-11-09       Impact factor: 3.315

Review 3.  Silver treatments and silver-impregnated dressings for the healing of leg wounds and ulcers: a systematic review and meta-analysis.

Authors:  Marissa J Carter; Kimberly Tingley-Kelley; Robert A Warriner
Journal:  J Am Acad Dermatol       Date:  2010-05-14       Impact factor: 11.527

4.  Classification of wounds at risk and their antimicrobial treatment with polihexanide: a practice-oriented expert recommendation.

Authors:  J Dissemond; O Assadian; V Gerber; A Kingsley; A Kramer; D J Leaper; G Mosti; A Piatkowski de Grzymala; G Riepe; A Risse; M Romanelli; R Strohal; J Traber; A Vasel-Biergans; T Wild; T Eberlein
Journal:  Skin Pharmacol Physiol       Date:  2011-04-20       Impact factor: 3.479

5.  [Patch testing in patients with leg ulcers with special regard to modern wound products].

Authors:  S Reich-Schupke; J Kurscheidt; C Appelhans; A Kreuter; P Altmeyer; M Stücker
Journal:  Hautarzt       Date:  2010-07       Impact factor: 0.751

6.  Impact of Pseudomonas aeruginosa quorum sensing on cellular wound healing responses in vitro.

Authors:  Jasper N Jacobsen; Anders S Andersen; Karen A Krogfelt
Journal:  Scand J Infect Dis       Date:  2012-02-19

Review 7.  Antibiotics and antiseptics for venous leg ulcers.

Authors:  Susan O'Meara; Deyaa Al-Kurdi; Yemisi Ologun; Liza G Ovington
Journal:  Cochrane Database Syst Rev       Date:  2010-01-20

8.  The biocide polyhexamethylene biguanide remains an uncommon contact allergen.

Authors:  Axel Schnuch; Johannes Geier; Wolfgang Uter; David A Basketter; Ian R Jowsey
Journal:  Contact Dermatitis       Date:  2007-04       Impact factor: 6.600

Review 9.  Water for wound cleansing.

Authors:  Ritin Fernandez; Rhonda Griffiths
Journal:  Cochrane Database Syst Rev       Date:  2012-02-15

10.  Success rate of split-thickness skin grafting of chronic venous leg ulcers depends on the presence of Pseudomonas aeruginosa: a retrospective study.

Authors:  Trine Høgsberg; Thomas Bjarnsholt; Jens Schiersing Thomsen; Klaus Kirketerp-Møller
Journal:  PLoS One       Date:  2011-05-31       Impact factor: 3.240

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  2 in total

1.  Impact of Gram-negative bacteria on the treatment of venous leg ulcers.

Authors:  Wibke L Engelberg; Martin Dörler; Markus Stücker; Stefanie Reich-Schupke
Journal:  Int Wound J       Date:  2018-08-05       Impact factor: 3.315

2.  Bioshell Calcium Oxide (BiSCaO) Ointment for the Disinfection and Healing of Pseudomonas aeruginosa-Infected Wounds in Hairless Rats.

Authors:  Tomohiro Takayama; Masayuki Ishihara; Shingo Nakamura; Yoko Sato; Sumiyo Hiruma; Koichi Fukuda; Kaoru Murakami; Hidetaka Yokoe
Journal:  Int J Mol Sci       Date:  2020-06-11       Impact factor: 5.923

  2 in total

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