Literature DB >> 21508658

Classification of wounds at risk and their antimicrobial treatment with polihexanide: a practice-oriented expert recommendation.

J Dissemond1, O Assadian, V Gerber, A Kingsley, A Kramer, D J Leaper, G Mosti, A Piatkowski de Grzymala, G Riepe, A Risse, M Romanelli, R Strohal, J Traber, A Vasel-Biergans, T Wild, T Eberlein.   

Abstract

Currently, there are no generally accepted definitions for wounds at risk of infection. In clinical practice, too many chronic wounds are regarded as being at risk of infection, and therefore many topical antimicrobials - in terms of frequency and duration of use - are applied to wounds. Based on expert discussion and current knowledge, a clinical assessment score was developed. The objective of this wounds at risk (W.A.R.) score is to allow decision-making on the indication for the use of antiseptics on the basis of polihexanide. The proposed clinical classification of W.A.R. shall facilitate the decision for wound antisepsis and allow an appropriate general treatment regimen with the focus on the prevention of wound infection. The W.A.R. score is based on a clinically oriented risk assessment using concrete patient circumstances. The indication for the use of antiseptics results from the addition of differently weighted risk causes, for which points are assigned. Antimicrobial treatment is justified in the case of 3 or more points.
Copyright © 2011 S. Karger AG, Basel.

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Year:  2011        PMID: 21508658     DOI: 10.1159/000327210

Source DB:  PubMed          Journal:  Skin Pharmacol Physiol        ISSN: 1660-5527            Impact factor:   3.479


  13 in total

1.  Topical antiseptics in wound care: time for reflection.

Authors:  David Leaper
Journal:  Int Wound J       Date:  2011-12       Impact factor: 3.315

Review 2.  Recommendations on negative pressure wound therapy with instillation and antimicrobial solutions - when, where and how to use: what does the evidence show?

Authors:  David A Back; Catharina Scheuermann-Poley; Christian Willy
Journal:  Int Wound J       Date:  2013-12       Impact factor: 3.315

Review 3.  [Wound dressings. Overview and classification].

Authors:  T Horn
Journal:  Unfallchirurg       Date:  2012-09       Impact factor: 1.000

Review 4.  Extending the TIME concept: what have we learned in the past 10 years?(*).

Authors:  David J Leaper; Gregory Schultz; Keryln Carville; Jacqueline Fletcher; Theresa Swanson; Rebecca Drake
Journal:  Int Wound J       Date:  2012-12       Impact factor: 3.315

5.  Prospective, double-blinded, randomised controlled trial assessing the effect of an Octenidine-based hydrogel on bacterial colonisation and epithelialization of skin graft wounds in burn patients.

Authors:  Eisenbeiß W; Siemers F; Amtsberg G; Hinz P; Hartmann B; Kohlmann T; Ekkernkamp A; Albrecht U; Assadian O; Kramer A
Journal:  Int J Burns Trauma       Date:  2012-09-15

6.  [Chronic wounds and bacteria. Clinical relevance, detection and therapy].

Authors:  J Dissemond
Journal:  Hautarzt       Date:  2014-01       Impact factor: 0.751

7.  What COVID-19 taught us: New opportunities and pathways from telemedicine and novel antiseptics in wound healing.

Authors:  Alessandro Scalise; Marco Falcone; Giampiero Avruscio; Enrico Brocco; Eugenio Ciacco; Aurora Parodi; Rolando Tasinato; Elia Ricci
Journal:  Int Wound J       Date:  2021-10-02       Impact factor: 3.099

8.  The use of biatain Ag in hard-to-heal venous leg ulcers: meta-analysis of randomised controlled trials.

Authors:  David Leaper; Christian Münter; Sylvie Meaume; Alessandro Scalise; Nacho Blanes Mompó; Birte Petersen Jakobsen; Finn Gottrup
Journal:  PLoS One       Date:  2013-07-02       Impact factor: 3.240

9.  Bacterial growth kinetics under a novel flexible methacrylate dressing serving as a drug delivery vehicle for antiseptics.

Authors:  Christina Forstner; Johannes Leitgeb; Rupert Schuster; Verena Dosch; Axel Kramer; Keith F Cutting; David J Leaper; Ojan Assadian
Journal:  Int J Mol Sci       Date:  2013-05-21       Impact factor: 5.923

10.  Impact of cold atmospheric pressure argon plasma on antibiotic sensitivity of methicillin-resistant Staphylococcus aureus strains in vitro.

Authors:  Anne Lührmann; Rutger Matthes; Axel Kramer
Journal:  GMS Hyg Infect Control       Date:  2016-08-30
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