Literature DB >> 2433306

Chronic Theiler's virus infection in mice: appearance of myelin basic protein in the cerebrospinal fluid and serum antibody directed against MBP.

H C Rauch, I N Montgomery, C L Hinman, W Harb, J A Benjamins.   

Abstract

Myelin basic protein (MBP) appears frequently in the cerebrospinal fluid (CSF) of mice with chronic demyelination following intracerebral infection with Theiler's murine encephalomyelitis virus (TMEV); antibody to MBP can frequently be found in the sera. The peaks of the immune responses to both MBP and TMEV coincide with the time course of the clinical signs of disease. Adsorption of mouse sera with TMEV or MBP indicate the non-identity of the antigens and the specificity of the antisera as measured by ELISA. Immunoblot analysis of sera confirmed the ELISA findings. The mechanism of induction of antibody directed against MBP and its role in TMEV-associated demyelination remain to be determined.

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Year:  1987        PMID： 2433306      PMCID： PMC7119459          DOI： 10.1016/0165-5728(87)90099-3

Source DB:  PubMed          Journal:  J Neuroimmunol        ISSN： 0165-5728            Impact factor:   3.478


  31 in total

1.  The role of the immune response in TMEV infection and the development of late onset demyelination.

Authors:  H C Rauch; I N Montgomery
Journal:  J Immunol       Date:  1986-03-15       Impact factor: 5.422

2.  Theiler's virus antigen detected in mouse spinal cord 2 1/2 years after infection.

Authors:  H L Lipton; J Kratochvil; P Sethi; M C Dal Canto
Journal:  Neurology       Date:  1984-08       Impact factor: 9.910

3.  Sequence homology between certain viral proteins and proteins related to encephalomyelitis and neuritis.

Authors:  U Jahnke; E H Fischer; E C Alvord
Journal:  Science       Date:  1985-07-19       Impact factor: 47.728

4.  Endogenous myelin basic protein-serum factors (MBP-SFS) and anti-MBP antibodies in a patient with post-herpes simplex virus acute disseminated encephalomyelitis.

Authors:  S G Rabinowitz; E D Day; P Y Paterson; H Koenig
Journal:  J Neurol Sci       Date:  1983 Aug-Sep       Impact factor: 3.181

5.  Electroblot analysis of the myelin proteolipid protein.

Authors:  W B Macklin; P E Braun; M B Lees
Journal:  J Neurosci Res       Date:  1982       Impact factor: 4.164

6.  Theiler's virus-induced demyelination: prevention by immunosuppression.

Authors:  H L Lipton; M C Dal Canto
Journal:  Science       Date:  1976-04-02       Impact factor: 47.728

7.  Contrasting effects of immunosuppression on Theiler's virus infection in mice.

Authors:  H L Lipton; C D Canto
Journal:  Infect Immun       Date:  1977-03       Impact factor: 3.441

8.  Characterization of Theiler's murine encephalomyelitis virus (TMEV)-specific delayed-type hypersensitivity responses in TMEV-induced demyelinating disease: correlation with clinical signs.

Authors:  R J Clatch; H L Lipton; S D Miller
Journal:  J Immunol       Date:  1986-02-01       Impact factor: 5.422

9.  Epstein-Barr virus-transformed lymphocytes produce monoclonal autoantibodies that react with antigens in multiple organs.

Authors:  C Garzelli; F E Taub; J E Scharff; B S Prabhakar; F Ginsberg-Fellner; A L Notkins
Journal:  J Virol       Date:  1984-11       Impact factor: 5.103

10.  The TO strains of Theiler's viruses cause "slow virus-like" infections in mice.

Authors:  H L Lipton; M C Dal Canto
Journal:  Ann Neurol       Date:  1979-07       Impact factor: 10.422
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  14 in total

1.  Immunization with structural and non-structural proteins of Theiler's murine encephalomyelitis virus alters demyelinating disease.

Authors:  Ikuo Tsunoda; Jane E Libbey; Robert S Fujinami
Journal:  J Neurovirol       Date:  2012-03-09       Impact factor: 2.643

2.  Central nervous system pathology caused by autoreactive CD8+ T-cell clones following virus infection.

Authors:  Ikuo Tsunoda; Li-Qing Kuang; Mikako Kobayashi-Warren; Robert S Fujinami
Journal:  J Virol       Date:  2005-12       Impact factor: 5.103

3.  Protective and detrimental roles for regulatory T cells in a viral model for multiple sclerosis.

Authors:  Nicholas E Martinez; Fridrik Karlsson; Fumitaka Sato; Eiichiro Kawai; Seiichi Omura; Alireza Minagar; Matthew B Grisham; Ikuo Tsunoda
Journal:  Brain Pathol       Date:  2014-02-25       Impact factor: 6.508

4.  Evaluating an etiologically relevant platform for therapy development for temporal lobe epilepsy: effects of carbamazepine and valproic acid on acute seizures and chronic behavioral comorbidities in the Theiler's murine encephalomyelitis virus mouse model.

Authors:  Melissa L Barker-Haliski; E Jill Dahle; Taylor D Heck; Timothy H Pruess; Fabiola Vanegas; Karen S Wilcox; H Steve White
Journal:  J Pharmacol Exp Ther       Date:  2015-03-09       Impact factor: 4.030

5.  Prolonged gray matter disease without demyelination caused by Theiler's murine encephalomyelitis virus with a mutation in VP2 puff B.

Authors:  I Tsunoda; Y Wada; J E Libbey; T S Cannon; F G Whitby; R S Fujinami
Journal:  J Virol       Date:  2001-08       Impact factor: 5.103

Review 6.  Theiler's virus infection: a model for multiple sclerosis.

Authors:  Emilia L Oleszak; J Robert Chang; Herman Friedman; Christos D Katsetos; Chris D Platsoucas
Journal:  Clin Microbiol Rev       Date:  2004-01       Impact factor: 26.132

Review 7.  CB2 cannabinoid receptors as an emerging target for demyelinating diseases: from neuroimmune interactions to cell replacement strategies.

Authors:  A Arévalo-Martín; D García-Ovejero; O Gómez; A Rubio-Araiz; B Navarro-Galve; C Guaza; E Molina-Holgado; F Molina-Holgado
Journal:  Br J Pharmacol       Date:  2007-09-24       Impact factor: 8.739

Review 8.  Immunology of Theiler's murine encephalomyelitis virus infection.

Authors:  E L Oleszak; J Kuzmak; R A Good; C D Platsoucas
Journal:  Immunol Res       Date:  1995       Impact factor: 2.829

9.  DNA vaccination against Theiler's murine encephalomyelitis virus leads to alterations in demyelinating disease.

Authors:  N D Tolley; I Tsunoda; R S Fujinami
Journal:  J Virol       Date:  1999-02       Impact factor: 5.103

Review 10.  Excessive Innate Immunity Steers Pathogenic Adaptive Immunity in the Development of Theiler's Virus-Induced Demyelinating Disease.

Authors:  Byung S Kim
Journal:  Int J Mol Sci       Date:  2021-05-17       Impact factor: 5.923
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