Literature DB >> 6087205

Theiler's virus antigen detected in mouse spinal cord 2 1/2 years after infection.

H L Lipton, J Kratochvil, P Sethi, M C Dal Canto.   

Abstract

Spinal cord sections from mice injected with Theiler's murine encephalomyelitis virus (TMEV) and surviving for 1 year and longer after infection were stained for virus antigen by two immunohistochemical techniques. Virus antigen was detected from 1 to 2 1/2 years after infection, a time when no virus was recovered at an assay sensitivity of 50 plaque-forming units per gram of tissue. The implication this has regarding the detection of a virus in MS is discussed.

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Year:  1984        PMID： 6087205     DOI： 10.1212/wnl.34.8.1117

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  42 in total

1.  Two loci, Tmevp2 and Tmevp3, located on the telomeric region of chromosome 10, control the persistence of Theiler's virus in the central nervous system of mice.

Authors:  F Bihl; M Brahic; J F Bureau
Journal:  Genetics       Date:  1999-05       Impact factor: 4.562

2.  Viral load increases in SJL/J mice persistently infected by Theiler's virus after inactivation of the beta(2)m gene.

Authors:  S Aubagnac; M Brahic; J F Bureau
Journal:  J Virol       Date:  2001-08       Impact factor: 5.103

3.  Bone marrow chimeras reveal non-H-2 hematopoietic control of susceptibility to Theiler's virus persistent infection.

Authors:  Stéphanie Aubagnac; Michel Brahic; Jean-François Bureau
Journal:  J Virol       Date:  2002-06       Impact factor: 5.103

4.  CD28 costimulatory blockade exacerbates disease severity and accelerates epitope spreading in a virus-induced autoimmune disease.

Authors:  K L Neville; M C Dal Canto; J A Bluestone; S D Miller
Journal:  J Virol       Date:  2000-09       Impact factor: 5.103

5.  Differences in avidity and epitope recognition of CD8(+) T cells infiltrating the central nervous systems of SJL/J mice infected with BeAn and DA strains of Theiler's murine encephalomyelitis virus.

Authors:  Bong-Su Kang; Michael A Lyman; Byung S Kim
Journal:  J Virol       Date:  2002-11       Impact factor: 5.103

6.  The interaction of two groups of murine genes determines the persistence of Theiler's virus in the central nervous system.

Authors:  J F Bureau; X Montagutelli; S Lefebvre; J L Guénet; M Pla; M Brahic
Journal:  J Virol       Date:  1992-08       Impact factor: 5.103

7.  Preferential induction of protective T cell responses to Theiler's virus in resistant (C57BL/6 x SJL)F1 mice.

Authors:  Young-Hee Jin; Hyun Seok Kang; Mani Mohindru; Byung S Kim
Journal:  J Virol       Date:  2010-12-29       Impact factor: 5.103

Review 8.  Nucleic acid detection systems for enteroviruses.

Authors:  H A Rotbart
Journal:  Clin Microbiol Rev       Date:  1991-04       Impact factor: 26.132

9.  Role of the humoral immune response in resistance to Theiler's virus infection.

Authors:  C P Rossi; E Cash; C Aubert; A Coutinho
Journal:  J Virol       Date:  1991-07       Impact factor: 5.103

10.  Differential virus replication, cytokine production, and antigen-presenting function by microglia from susceptible and resistant mice infected with Theiler's virus.

Authors:  Young-Hee Jin; Mani Mohindru; Min H Kang; Alyson C Fuller; Bongsu Kang; Daniel Gallo; Byung S Kim
Journal:  J Virol       Date:  2007-08-22       Impact factor: 5.103
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