Literature DB >> 24314746

Withanolides from Jaborosa caulescens var. bipinnatifida.

Huaping Zhang1, Cong-Mei Cao1, Robert J Gallagher1, Victor W Day2, Gloria Montenegro3, Barbara N Timmermann4.   

Abstract

Withanolides 2,3-dihydrotrechonolide A (1) and 2,3-dihydro-21-hydroxytrechonolide A (2) were isolated along with two known withanolides trechonolide A (3) and jaborosalactone 39 (4) from Jaborosa caulescens var. bipinnatifida (Solanaceae). The structures of 1-2 were elucidated through 2D NMR and other spectroscopic techniques. In addition, the structure of withanolide 1 was confirmed by X-ray crystallographic analysis.
Copyright © 2013 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  2,3-Dihydro-21-hydroxytrechonolide A; 2,3-Dihydrotrechonolide A; Jaborosa caulescens var. bipinnatifida; Solanaceae; Withanolide

Mesh:

Substances:

Year:  2013        PMID: 24314746      PMCID: PMC3947017          DOI: 10.1016/j.phytochem.2013.11.005

Source DB:  PubMed          Journal:  Phytochemistry        ISSN: 0031-9422            Impact factor:   4.072


  10 in total

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Journal:  J Nat Prod       Date:  2003-08       Impact factor: 4.050

2.  Withaferin A, a cytotoxic steroid from Vassobia breviflora, induces apoptosis in human head and neck squamous cell carcinoma.

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Review 3.  Withanolides and related steroids.

Authors:  Rosana I Misico; Viviana E Nicotra; Juan C Oberti; Gloria Barboza; Roberto R Gil; Gerardo Burton
Journal:  Prog Chem Org Nat Prod       Date:  2011

Review 4.  Natural withanolides: an overview.

Authors:  Li-Xia Chen; Hao He; Feng Qiu
Journal:  Nat Prod Rep       Date:  2011-02-23       Impact factor: 13.423

5.  Chlorinated Withanolides from Withania somnifera.

Authors:  Xiaoqin Tong; Huaping Zhang; Barbara N Timmermann
Journal:  Phytochem Lett       Date:  2011-12       Impact factor: 1.679

6.  Cytotoxic withanolide constituents of Physalis longifolia.

Authors:  Huaping Zhang; Abbas K Samadi; Robert J Gallagher; Juan J Araya; Xiaoqin Tong; Victor W Day; Mark S Cohen; Kelly Kindscher; Rao Gollapudi; Barbara N Timmermann
Journal:  J Nat Prod       Date:  2011-11-18       Impact factor: 4.050

7.  Minor withanolides of Physalis longifolia: structure and cytotoxicity.

Authors:  Huaping Zhang; Hashim Motiwala; Abbas Samadi; Victor Day; Jeffrey Aubé; Mark Cohen; Kelly Kindscher; Rao Gollapudi; Barbara Timmermann
Journal:  Chem Pharm Bull (Tokyo)       Date:  2012       Impact factor: 1.645

8.  Antiproliferative withanolides from Datura wrightii.

Authors:  Huaping Zhang; Joseph Bazzill; Robert J Gallagher; Chitra Subramanian; Patrick T Grogan; Victor W Day; Kelly Kindscher; Mark S Cohen; Barbara N Timmermann
Journal:  J Nat Prod       Date:  2012-12-19       Impact factor: 4.050

9.  Withanolides with phytotoxic activity from Jaborosa caulescens var. caulescens and J. caulescens var. bipinnatifida 1.

Authors:  Viviana E Nicotra; Roberto R Gil; Juan C Oberti; Gerardo Burton
Journal:  J Nat Prod       Date:  2007-04-12       Impact factor: 4.050

10.  Anti-proliferative withanolides from the Solanaceae: a structure-activity study.

Authors:  Huaping Zhang; Abbas K Samadi; Mark S Cohen; Barbara N Timmermann
Journal:  Pure Appl Chem       Date:  2012       Impact factor: 2.453

  10 in total
  1 in total

Review 1.  Antiproliferative withanolides from several solanaceous species.

Authors:  Huaping Zhang; Cong-Mei Cao; Robert J Gallagher; Barbara N Timmermann
Journal:  Nat Prod Res       Date:  2014-05-28       Impact factor: 2.861

  1 in total

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