PURPOSE: Urinary tract infection (UTI) is the most common nosocomial infection among hospitalized patients. Meanwhile, most frequent infections involving enterococci affect the urinary tract. The aims of this study were to investigate the susceptibility pattern of isolated enterococci from UTI and the prevalence of virulence genes. METHODS: The study used enterococci isolated from urinary tract infections obtained from 3 university teaching hospitals in Northwest Iran. The antimicrobial susceptibility of the strains was determined using the disc diffusion method. Multiplex PCR was performed for the detection of genus- species specific targets, and potential virulence genes. RESULTS: Of 188 enterococcal isolates, 138 (73.4%) and 50 (26.6%) were Enterococcus faecalis and E. faecium, respectively. Antibiotic susceptibility testing showed high resistance to amikacin (86.2%), rifampicin (86.2%) and erythromycin (73.9%), irrespective of species. In total, 68.1% were positive for gelE, and 57.4%, 53.2%, 56.4%, and 52.1% of isolates were positive for cpd, asa1, ace, and esp, respectively. CONCLUSION: The study revealed that most of UTI isolates were multidrug resistance against the antibiotics tested and antibiotic resistance was more common among E. faecium isolates than E. faecalis. A significant correlation was found between UTI and the presence of gelE among E. faecalis strains (p < 0.001).
PURPOSE:Urinary tract infection (UTI) is the most common nosocomial infection among hospitalized patients. Meanwhile, most frequent infections involving enterococci affect the urinary tract. The aims of this study were to investigate the susceptibility pattern of isolated enterococci from UTI and the prevalence of virulence genes. METHODS: The study used enterococci isolated from urinary tract infections obtained from 3 university teaching hospitals in Northwest Iran. The antimicrobial susceptibility of the strains was determined using the disc diffusion method. Multiplex PCR was performed for the detection of genus- species specific targets, and potential virulence genes. RESULTS: Of 188 enterococcal isolates, 138 (73.4%) and 50 (26.6%) were Enterococcus faecalis and E. faecium, respectively. Antibiotic susceptibility testing showed high resistance to amikacin (86.2%), rifampicin (86.2%) and erythromycin (73.9%), irrespective of species. In total, 68.1% were positive for gelE, and 57.4%, 53.2%, 56.4%, and 52.1% of isolates were positive for cpd, asa1, ace, and esp, respectively. CONCLUSION: The study revealed that most of UTI isolates were multidrug resistance against the antibiotics tested and antibiotic resistance was more common among E. faecium isolates than E. faecalis. A significant correlation was found between UTI and the presence of gelE among E. faecalis strains (p < 0.001).
Authors: N Klibi; S Gharbi; A Masmoudi; K Ben Slama; P Poeta; M Zarazaga; C Fendri; A Boudabous; C Torres Journal: J Chemother Date: 2006-02 Impact factor: 1.714
Authors: C Sabia; S de Niederhäusern; E Guerrieri; P Messi; I Anacarso; G Manicardi; M Bondi Journal: J Appl Microbiol Date: 2007-11-14 Impact factor: 3.772
Authors: Hikmate Abriouel; Nabil Ben Omar; Antonio Cobo Molinos; Rosario Lucas López; Maria José Grande; Pilar Martínez-Viedma; Elena Ortega; Magdalena Martínez Cañamero; Antonio Galvez Journal: Int J Food Microbiol Date: 2007-12-04 Impact factor: 5.277
Authors: Mohammed A Samad; Md Shahjalal Sagor; Muhammad Sazzad Hossain; Md Rezaul Karim; Mohammad Asheak Mahmud; Md Samun Sarker; Fahria A Shownaw; Zakaria Mia; Roderick M Card; Agnes Agunos; Lindahl Johanna Journal: Vet Res Commun Date: 2022-03-26 Impact factor: 2.816
Authors: Annette C Anderson; Daniel Jonas; Ingrid Huber; Lamprini Karygianni; Johan Wölber; Elmar Hellwig; Nicole Arweiler; Kirstin Vach; Annette Wittmer; Ali Al-Ahmad Journal: Front Microbiol Date: 2016-01-11 Impact factor: 5.640
Authors: Teresita D J Bello Gonzalez; Phu Pham; Janetta Top; Rob J L Willems; Willem van Schaik; Mark W J van Passel; Hauke Smidt Journal: Front Microbiol Date: 2017-08-28 Impact factor: 5.640