Literature DB >> 24306704

Origin of propionibacterium in surgical wounds and evidence-based approach for culturing propionibacterium from surgical sites.

Frederick A Matsen1, Susan Butler-Wu, Bradley C Carofino, Jocelyn L Jette, Alexander Bertelsen, Roger Bumgarner.   

Abstract

BACKGROUND: To explore the origin of Propionibacterium in surgical wounds and to suggest an optimized strategy for culturing this organism at the time of revision surgery, we studied the presence of this organism on the skin and in the surgical wounds of patients who underwent revision arthroplasty for reasons other than apparent infection.
METHODS: Specimens were cultured in broth and on aerobic and anaerobic media. The presence and degree of positivity of Propionibacterium cultures were correlated with sex. The results of dermal and deep cultures were correlated. Times to positivity and the yields of each media type and specimen source were investigated.
RESULTS: Propionibacterium grew in twenty-three of thirty cultures of specimens obtained preoperatively from the unprepared epidermis over the area where a skin incision was going to be made for a shoulder arthroplasty; males had a greater average degree of positivity than females (p < 0.002). Twelve of twenty-one male subjects and zero of twenty female subjects who had cultures of dermal specimens obtained during revision shoulder arthroplasty had positive findings for Propionibacterium (p = 0.0001). Twelve of twenty male subjects and only one of twenty female subjects had positive deep cultures (p = 0.0004). The positivity of dermal cultures for Propionibacterium was significantly associated with the positivity of deep cultures for this organism (p = 0.0001). If Propionibacterium was present in deep tissues, it was likely that it would be recovered by culture if four different specimens were obtained and cultured for a minimum of seventeen days on three different media: aerobic, anaerobic, and broth.
CONCLUSIONS: Because the surgical incision of dermal sebaceous glands may be a source of Propionibacterium in deep wounds, strategies for minimizing the risk of Propionibacterium infections may need to be directed at minimizing the contamination of surgical wounds from these bacteria residing in rather than on the skin. Obtaining at least four specimens, observing them for seventeen days, and using three types of culture media optimize the recovery of Propionibacterium at the time of revision surgery.

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Year:  2013        PMID: 24306704      PMCID: PMC4098017          DOI: 10.2106/JBJS.L.01733

Source DB:  PubMed          Journal:  J Bone Joint Surg Am        ISSN: 0021-9355            Impact factor:   5.284


  46 in total

1.  Infection after mini-open rotator cuff repair.

Authors:  Mauricio F Herrera; Greg Bauer; Fletcher Reynolds; Richard M Wilk; Louis U Bigliani; William N Levine
Journal:  J Shoulder Elbow Surg       Date:  2002 Nov-Dec       Impact factor: 3.019

2.  Corrosion and late infection causing delayed paraparesis after spinal instrumentation.

Authors:  José Beguiristain; Javier del Río; Julio Duart; José Barroso; Alvaro Silva; Carlos Villas
Journal:  J Pediatr Orthop B       Date:  2006-09       Impact factor: 1.041

3.  Revision shoulder arthroplasty with positive intraoperative cultures: the value of preoperative studies and intraoperative histology.

Authors:  Mark S Topolski; Patrick Y K Chin; John W Sperling; Robert H Cofield
Journal:  J Shoulder Elbow Surg       Date:  2006 Jul-Aug       Impact factor: 3.019

4.  Late implant infections caused by Propionibacterium acnes in scoliosis surgery.

Authors:  Frederik Hahn; Reinhard Zbinden; Kan Min
Journal:  Eur Spine J       Date:  2005-04-20       Impact factor: 3.134

5.  Characteristics of unsatisfactory shoulder arthroplasties.

Authors:  Samer S Hasan; Jordan M Leith; Barry Campbell; Ranjit Kapil; Kevin L Smith; Frederick A Matsen
Journal:  J Shoulder Elbow Surg       Date:  2002 Sep-Oct       Impact factor: 3.019

6.  Propionibacterium acnes wound contamination at the time of spinal surgery.

Authors:  Gregory C McLorinan; Josephine V Glenn; Michael G McMullan; Sheila Patrick
Journal:  Clin Orthop Relat Res       Date:  2005-08       Impact factor: 4.176

7.  Delayed infections after posterior TSRH spinal instrumentation for idiopathic scoliosis: revisited.

Authors:  B R Richards; K M Emara
Journal:  Spine (Phila Pa 1976)       Date:  2001-09-15       Impact factor: 3.468

8.  Propionibacterium acnes types I and II represent phylogenetically distinct groups.

Authors:  Andrew McDowell; Susanna Valanne; Gordon Ramage; Michael M Tunney; Josephine V Glenn; Gregory C McLorinan; Ajay Bhatia; Jean-Francois Maisonneuve; Michael Lodes; David H Persing; Sheila Patrick
Journal:  J Clin Microbiol       Date:  2005-01       Impact factor: 5.948

9.  Detection of prosthetic hip infection at revision arthroplasty by immunofluorescence microscopy and PCR amplification of the bacterial 16S rRNA gene.

Authors:  M M Tunney; S Patrick; M D Curran; G Ramage; D Hanna; J R Nixon; S P Gorman; R I Davis; N Anderson
Journal:  J Clin Microbiol       Date:  1999-10       Impact factor: 5.948

10.  Full-thickness thoracic laminar erosion after posterior spinal fusion associated with late-presenting infection.

Authors:  Clifford B Tribus; Kathleen E Garvey
Journal:  Spine (Phila Pa 1976)       Date:  2003-05-15       Impact factor: 3.468

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  38 in total

Review 1.  What is a "periprosthetic shoulder infection"? A systematic review of two decades of publications.

Authors:  Jason E Hsu; Jeremy S Somerson; Kiet V Vo; Frederick A Matsen
Journal:  Int Orthop       Date:  2017-02-21       Impact factor: 3.075

2.  Cutibacterium acnes (formerly Proprionibacterium acnes) and Shoulder Surgery.

Authors:  Marlee J Elston; John P Dupaix; Maria I Opanova; Robert E Atkinson
Journal:  Hawaii J Health Soc Welf       Date:  2019-11

Review 3.  Ten questions on prosthetic shoulder infection.

Authors:  Elizabeth M Pinder; Joshua Cy Ong; R Stephen Bale; Ian A Trail
Journal:  Shoulder Elbow       Date:  2016-03-08

4.  Utility of strain typing of Propionibacterium acnes in central nervous system and prosthetic joint infections to differentiate contamination from infection: a retrospective cohort.

Authors:  J P Burnham; A Shupe; C-A D Burnham; D K Warren
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2017-08-25       Impact factor: 3.267

5.  Cutibacterium acnes Isolates from Deep Tissue Specimens Retrieved during Revision Shoulder Arthroplasty: Similar Colony Morphology Does Not Indicate Clonality.

Authors:  Roger E Bumgarner; Della Harrison; Jason E Hsu
Journal:  J Clin Microbiol       Date:  2020-01-28       Impact factor: 5.948

6.  Is Propionibacterium acnes becoming the most common bacteria in delayed infections following adolescent idiopathic scoliosis surgery?

Authors:  Mayur P Kardile; Sukhraj S Bains; Calvin C Kuo; Todd L Lincoln; Ravi S Bains
Journal:  Spine Deform       Date:  2021-02-08

7.  Method of intraoperative tissue sampling for culture has an effect on contamination risk.

Authors:  Antonia F Chen; Meredith Menz; Priscilla K Cavanaugh; Javad Parvizi
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2016-09-12       Impact factor: 4.342

8.  What Factors are Predictive of Patient-reported Outcomes? A Prospective Study of 337 Shoulder Arthroplasties.

Authors:  Frederick A Matsen; Stacy M Russ; Phuong T Vu; Jason E Hsu; Robert M Lucas; Bryan A Comstock
Journal:  Clin Orthop Relat Res       Date:  2016-07-25       Impact factor: 4.176

9.  Infections following arthroscopic rotator cuff repair: incidence, risk factors, and prophylaxis.

Authors:  Leo Pauzenberger; Annemarie Grieb; Michael Hexel; Brenda Laky; Werner Anderl; Philipp Heuberer
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2016-06-24       Impact factor: 4.342

10.  Acute infection with Propionibacterium acnes after a Latarjet coracoid transfer procedure: a case report.

Authors:  Brandon J Erickson; Sanjeev Bhatia; Debdut Biswas; Nikhil N Verma
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2014-09-11       Impact factor: 4.342

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