Literature DB >> 33555598

Is Propionibacterium acnes becoming the most common bacteria in delayed infections following adolescent idiopathic scoliosis surgery?

Mayur P Kardile1, Sukhraj S Bains2, Calvin C Kuo1, Todd L Lincoln1, Ravi S Bains3.   

Abstract

STUDY
DESIGN: Retrospective review of hospital charts.
OBJECTIVE: (1) To determine the microbiological profile of patients with surgical site infections following posterior spinal fusion surgery (PSF) for Adolescent Idiopathic scoliosis (AIS). (2) To study the treatment outcome of patients with surgical site infections (SSI) following surgery for AIS. (3) To identify the key differences in presentation and management of acute and delayed SSI following AIS surgery. There has been increasing evidence of the role of P. acnes in deep surgical site infections. Literature related to this is abundant in relation to shoulder arthroplasty; however, it is sparse in relation to spine surgery.
METHODS: We conducted a retrospective review of all patients treated for AIS during a 5-year period (2010-2014) at our institution, with a minimum of 2-year follow-up after the index surgery. Patients with a postoperative infection following their index surgery were included. Charts of AIS patients with post-op infections were reviewed for details of the index surgery, time to presentation of the infection, presenting signs/symptoms, microbiology details, details of surgical and antibiotic treatment, and outcomes.
RESULTS: Nine (2.8%) post-op infections were identified out of 315 cases for AIS during this period. Seven (2.2%) involved P. acnes. Two (0.6%) involved MSSA. The average time for cultures to show growth was 6.1 days (range 5-8 days) in P. acnes group and 2-3 days in MSSA group. Patients with P. acnes infections were treated with implant removal, debridement and antibiotics. All patients achieved solid fusion except two patients from the P. acnes group had pseudoarthrosis and had to undergo revision fusion.
CONCLUSION: Propionibacterium acnes was the single most common bacteria isolated from delayed surgical site infection following PSF in AIS patients. Optimal treatment consists of debridement, implant removal and antibiotics. These patients have high incidence of pseudoarthrosis. LEVEL OF EVIDENCE: Level IV.

Entities:  

Keywords:  Delayed; Infections; P acnes; Scoliosis; Surgery; Surgical site

Year:  2021        PMID: 33555598     DOI: 10.1007/s43390-020-00250-x

Source DB:  PubMed          Journal:  Spine Deform        ISSN: 2212-134X


  32 in total

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2.  Origin of propionibacterium in surgical wounds and evidence-based approach for culturing propionibacterium from surgical sites.

Authors:  Frederick A Matsen; Susan Butler-Wu; Bradley C Carofino; Jocelyn L Jette; Alexander Bertelsen; Roger Bumgarner
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3.  Propionibacterium acnes wound contamination at the time of spinal surgery.

Authors:  Gregory C McLorinan; Josephine V Glenn; Michael G McMullan; Sheila Patrick
Journal:  Clin Orthop Relat Res       Date:  2005-08       Impact factor: 4.176

4.  Safety of instrumentation in patients with spinal infection.

Authors:  Mahmoud Rayes; Chaim B Colen; Diaa A Bahgat; Tetsuhiro Higashida; Murali Guthikonda; Setti Rengachary; Hazem A Eltahawy
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5.  Postoperative spine and VEPTR infections in children: a case-control study.

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6.  The microbial ecology of pilosebaceous units isolated from human skin.

Authors:  J P Leeming; K T Holland; W J Cunliffe
Journal:  J Gen Microbiol       Date:  1984-04

7.  Prevalence of intraoperative tissue bacterial contamination in posterior pediatric spinal deformity surgery.

Authors:  Sreeharsha V Nandyala; Richard M Schwend
Journal:  Spine (Phila Pa 1976)       Date:  2013-04-15       Impact factor: 3.468

8.  Biofilm formation by Propionibacterium acnes is a characteristic of invasive isolates.

Authors:  A Holmberg; R Lood; M Mörgelin; B Söderquist; E Holst; M Collin; B Christensson; M Rasmussen
Journal:  Clin Microbiol Infect       Date:  2009-04-23       Impact factor: 8.067

9.  Does nuclear tissue infected with bacteria following disc herniations lead to Modic changes in the adjacent vertebrae?

Authors:  Hanne B Albert; Peter Lambert; Jess Rollason; Joan Solgaard Sorensen; Tony Worthington; Mogens Bach Pedersen; Hanne Schack Nørgaard; Ann Vernallis; Frederik Busch; Claus Manniche; Tom Elliott
Journal:  Eur Spine J       Date:  2013-02-10       Impact factor: 3.134

10.  Propionibacterium acnes: an agent of prosthetic joint infection and colonization.

Authors:  Valérie Zeller; Ali Ghorbani; Christophe Strady; Philippe Leonard; Patrick Mamoudy; Nicole Desplaces
Journal:  J Infect       Date:  2007-04-05       Impact factor: 6.072

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  1 in total

1.  Indolent Infection After Lumbar Interbody Fusion: An Under-recognized Cause of Pseudarthrosis, Which Can Be Successfully Treated With Anterior Revision Fusion.

Authors:  Andrew S Zhang; Ellis M Berns; Davis A Hartnett; Eren O Kuris; Alan H Daniels
Journal:  J Am Acad Orthop Surg Glob Res Rev       Date:  2022-03-02
  1 in total

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