Literature DB >> 24306553

Clinical significance of post-interventional cerebral hyperdensities after endovascular mechanical thrombectomy in acute ischaemic stroke.

Omid Nikoubashman1, Arno Reich, Mirco Gindullis, Katharina Frohnhofen, Rastislav Pjontek, Marc-Alexander Brockmann, Jörg B Schulz, Martin Wiesmann.   

Abstract

INTRODUCTION: This study aims to investigate the clinical significance of post-interventional cerebral hyperdensities (PCHD) after endovascular mechanical thrombectomy in acute ischaemic stroke.
METHODS: Data of 102 consecutive patients who received post-interventional CT scans within 4.5 h after mechanical thrombectomy were analysed retrospectively.
RESULTS: Sixty-two of 102 patients (60.8 %) had PCHD on their post-interventional CT scans. The most common site of PCHD was the basal ganglia. PCHD were persisting in 13 of 62 patients (21.0 %), and transient in the remaining 49 patients (79.0 %) within 24 h. Four patients with PCHD and four patients without PCHD suffered from parenchymal haemorrhage. Neither ASA nor Clopidogrel, Tirofiban or rtPA were risk factors for PCHD. Final infarction size was congruent with or bigger than areas of PCHD in 93.3 % of cases in our series.
CONCLUSION: PCHD was not a risk factor for parenchymal haemorrhage in our series. The occurrence of PCHD was strongly related to the prior presence of infarction. PCHD was also a strong predictor for final infarction size.

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Year:  2013        PMID: 24306553     DOI: 10.1007/s00234-013-1303-1

Source DB:  PubMed          Journal:  Neuroradiology        ISSN: 0028-3940            Impact factor:   2.804


  30 in total

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Authors:  Kyung-Yul Lee; Sang Won Han; Seo Hyun Kim; Hyo Seok Nam; Sung Whan Ahn; Dong Joon Kim; Sang Hyun Seo; Dong Ik Kim; Ji Hoe Heo
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2.  Two tales: hemorrhagic transformation but not parenchymal hemorrhage after thrombolysis is related to severity and duration of ischemia: MRI study of acute stroke patients treated with intravenous tissue plasminogen activator within 6 hours.

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Journal:  Stroke       Date:  2007-01-04       Impact factor: 7.914

3.  Risk factors for severe hemorrhagic transformation in ischemic stroke patients treated with recombinant tissue plasminogen activator: a secondary analysis of the European-Australasian Acute Stroke Study (ECASS II).

Authors:  V Larrue; R von Kummer R; A Müller; E Bluhmki
Journal:  Stroke       Date:  2001-02       Impact factor: 7.914

4.  t-PA-specific modulation of a human blood-brain barrier model involves plasmin-mediated activation of the Rho kinase pathway in astrocytes.

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Authors:  C Brockmann; J Scharf; I S Nölte; M Seiz; C Groden; M A Brockmann
Journal:  Clin Neuroradiol       Date:  2010-11-04       Impact factor: 3.649

6.  CT after intracranial intraarterial thrombolysis for acute stroke.

Authors:  S L Wildenhain; C A Jungreis; J Barr; J Mathis; L Wechsler; J A Horton
Journal:  AJNR Am J Neuroradiol       Date:  1994-03       Impact factor: 3.825

7.  Intracerebral hemorrhage after intravenous t-PA therapy for ischemic stroke. The NINDS t-PA Stroke Study Group.

Authors: 
Journal:  Stroke       Date:  1997-11       Impact factor: 7.914

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Authors:  Sébastien Soize; Coralie Barbe; Krzysztof Kadziolka; Laurent Estrade; Isabelle Serre; Laurent Pierot
Journal:  Neuroradiology       Date:  2013-05-05       Impact factor: 2.804

10.  Contrast enhancement and contrast extravasation on computed tomography after intra-arterial thrombolysis in patients with acute ischemic stroke.

Authors:  Woong Yoon; Jeong Jin Seo; Jae Kyu Kim; Ki Hyeon Cho; Jin Gyoon Park; Heoung Keun Kang
Journal:  Stroke       Date:  2004-02-26       Impact factor: 7.914

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  13 in total

1.  Infarct fogging on immediate postinterventional CT-a not infrequent occurrence.

Authors:  Sven Dekeyzer; Arno Reich; Ahmed E Othman; Martin Wiesmann; Omid Nikoubashman
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2.  Hyper-attenuating brain lesions on CT after ischemic stroke and thrombectomy are associated with final brain infarction.

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3.  Arteriovenous shunts and capillary blush as an early sign of basal ganglia infarction after successful mechanical intra-arterial thrombectomy in ischaemic stroke.

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Review 6.  [Mechanical thrombectomy: Acute complications and delayed sequelae].

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8.  Association between pre-treatment perfusion profile and cerebral edema after reperfusion therapies in ischemic stroke.

Authors:  Felix C Ng; Leonid Churilov; Nawaf Yassi; Timothy J Kleinig; Vincent Thijs; Teddy Y Wu; Darshan Shah; Helen M Dewey; Gagan Sharma; Patricia M Desmond; Bernard Yan; Mark W Parsons; Geoffrey A Donnan; Stephen M Davis; Peter J Mitchell; Bruce Cv Campbell
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9.  Initial experience with dual-layer detector spectral CT for diagnosis of blood or contrast after endovascular treatment for ischemic stroke.

Authors:  Marie Louise E Bernsen; Peter B Veendrick; Jasper M Martens; Milan E J Pijl; Jeannette Hofmeijer; Maarten J van Gorp
Journal:  Neuroradiology       Date:  2021-05-27       Impact factor: 2.804

10.  Contrast Staining may be Associated with Intracerebral Hemorrhage but Not Functional Outcome in Acute Ischemic Stroke Patients Treated with Endovascular Thrombectomy.

Authors:  Hong An; Wenbo Zhao; Jianguo Wang; Joshua C Wright; Omar Elmadhoun; Di Wu; Shuyi Shang; Chuanjie Wu; Chuanhui Li; Longfei Wu; Jian Chen; Jiangang Duan; Hongqi Zhang; Haiqing Song; Yuchuan Ding; Xunming Ji
Journal:  Aging Dis       Date:  2019-08-01       Impact factor: 6.745

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