| Literature DB >> 24298422 |
Giulia M R De Luca1, Ronald M P Breedijk, Rick A J Brandt, Christiaan H C Zeelenberg, Babette E de Jong, Wendy Timmermans, Leila Nahidi Azar, Ron A Hoebe, Sjoerd Stallinga, Erik M M Manders.
Abstract
We present a new super-resolution technique, Re-scan Confocal Microscopy (RCM), based on standard confocal microscopy extended with an optical (re-scanning) unit that projects the image directly on a CCD-camera. This new microscope has improved lateral resolution and strongly improved sensitivity while maintaining the sectioning capability of a standard confocal microscope. This simple technology is typically useful for biological applications where the combination high-resolution and high-sensitivity is required.Entities:
Keywords: (110.2990) Image formation theory; (170.5810) Scanning microscopy; (170.6900) Three-dimensional microscopy; (180.1790) Confocal microscopy; (350.5730) Resolution
Year: 2013 PMID: 24298422 PMCID: PMC3829557 DOI: 10.1364/BOE.4.002644
Source DB: PubMed Journal: Biomed Opt Express ISSN: 2156-7085 Impact factor: 3.732