| Literature DB >> 24290123 |
Marco A Zarbin1, Timothy Arlow, Robert Ritch.
Abstract
Herein, we discuss recent applications of nanotechnology to ophthalmology, including nanoparticles for drug, gene, and trophic factor delivery; regenerative medicine (in the areas of optogenetics and optic nerve regeneration); and diagnostics (eg, minimally invasive biometric monitoring). Specific applications for the management of choroidal neovascularization, retinal neovascularization, oxidative damage, optic nerve damage, and retinal degenerative disease are considered. Nanotechnology will play an important role in early- and late-stage interventions in the management of blinding diseases.Entities:
Keywords: AAQ; CNV; ChR2; ECM; GDNF; HaloR; IOP; PCL; PEDF; PEG; RGC; RPE; VEGF; acrylamide-azobenzene-quaternary ammonium; channelrhodopsin-2; choroidal new vessel; extracellular matrix; glial cell line–derived neurotrophic factor; halorhodopsin; intraocular pressure; pigment epithelium–derived factor; poly(ε-caprolactone); polyethylene glycol; retinal ganglion cell; retinal pigment epithelium; shRNA; short hairpin RNA; siRNA; small interfering RNA; vascular endothelial growth factor
Mesh：
Year: 2013 PMID： 24290123 DOI： 10.1016/j.mayocp.2013.05.025
Source DB: PubMed Journal: Mayo Clin Proc ISSN： 0025-6196 Impact factor: 7.616