Literature DB >> 24286257

Reusable heat-sensitive phantom for precise estimation of thermal profile in hyperthermia application.

Ali Dabbagh1, Basri Johan Jeet Abdullah, Noor Hayaty Abu Kasim, Chanthiriga Ramasindarum.   

Abstract

PURPOSE: The emergence of thermal modalities has promoted the use of heat-sensitive phantoms for calibration, measurement, and verification purposes. However, development of durable phantoms with high precision ability to represent the temperature distribution remains a challenge. This study aims to introduce a reusable phantom that provides an accurate assessment of the heated region in various thermal modalities.
MATERIALS AND METHODS: The phantom contains a thermochromic dye that is transparent blue at room temperature and becomes colourless after exceeding a threshold temperature. In order to determine the threshold temperature of the phantom, spectrophotometry analysis was performed. The various thermal (specific heat, thermal conductivity, melting point and latent heat of melting) and acoustic (sound speed, attenuation) properties of this phantom were measured and compared with those of the reference phantom without dye. The application of this phantom for radio-frequency and magnetic resonance guided focused ultrasound modalities was also examined.
RESULTS: The spectrophotometry analysis showed a threshold temperature of 50 ± 3 °C for this phantom. The results also demonstrated a 6 °C difference between the onset and ending temperatures of the discolouration process. Moreover, the starting temperature of colouration during cooling was found to be 4 °C lower than the ending temperature of discolouration. The sound speed, attenuation, specific heat, thermal conductivity and melting point of the heat-sensitive phantom were statistically equal to those of the reference phantom; however, the latent heat, and onset temperature of the melting of the heat-sensitive phantom were decreased by addition of the dye.
CONCLUSIONS: The developed phantom is applicable for accurate evaluation of temperature variations in various thermal modalities.

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Year:  2013        PMID: 24286257     DOI: 10.3109/02656736.2013.854930

Source DB:  PubMed          Journal:  Int J Hyperthermia        ISSN: 0265-6736            Impact factor:   3.914


  7 in total

1.  Evaluation of a tissue-mimicking thermochromic phantom for radiofrequency ablation.

Authors:  Andrew S Mikhail; Ayele H Negussie; Cole Graham; Manoj Mathew; Bradford J Wood; Ari Partanen
Journal:  Med Phys       Date:  2016-07       Impact factor: 4.071

2.  A simple method for determining the coagulation threshold temperature of transparent tissue-mimicking thermal therapy gel phantoms: Validated by magnetic resonance imaging thermometry.

Authors:  N Patrik Brodin; Ari Partanen; Patrik Asp; Craig A Branch; Chandan Guha; Wolfgang A Tomé
Journal:  Med Phys       Date:  2016-03       Impact factor: 4.071

3.  A tissue-mimicking prostate phantom for 980 nm laser interstitial thermal therapy.

Authors:  R Geoghegan; A Santamaria; A Priester; L Zhang; H Wu; W Grundfest; L Marks; S Natarajan
Journal:  Int J Hyperthermia       Date:  2019       Impact factor: 3.914

4.  Thermochromic tissue-mimicking phantom for optimisation of thermal tumour ablation.

Authors:  Ayele H Negussie; Ari Partanen; Andrew S Mikhail; Sheng Xu; Nadine Abi-Jaoudeh; Subha Maruvada; Bradford J Wood
Journal:  Int J Hyperthermia       Date:  2016-04-20       Impact factor: 3.914

5.  A thermochromic tissue-mimicking phantom model for verification of ablation plans in thermal ablation.

Authors:  Yan Zhou; Lin Zhao; Xinyu Zhong; Jianmin Ding; Hongyu Zhou; Fengmei Wang; Xiang Jing
Journal:  Ann Transl Med       Date:  2021-02

6.  Controlled temperature-mediated curcumin release from magneto-thermal nanocarriers to kill bone tumors.

Authors:  A Khodaei; F Jahanmard; H R Madaah Hosseini; R Bagheri; A Dabbagh; H Weinans; S Amin Yavari
Journal:  Bioact Mater       Date:  2021-10-05

7.  Documentation of a New Intracavitary Applicator for Transrectal Hyperthermia Designed for Prostate Cancer Cases: A Phantom Study.

Authors:  Vassilis Kouloulias; Aggeliki Nikolakopoulou; Irene Karanasiou; Christos Antypas; Christina Armpilia; Nikolaos Uzunoglou
Journal:  J Med Phys       Date:  2018 Apr-Jun
  7 in total

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