Literature DB >> 2428613

Coordination of murine parotid secretory protein and salivary amylase expression.

K Poulsen, B K Jakobsen, B M Mikkelsen, K Harmark, J T Nielsen, J P Hjorth.   

Abstract

PSP, parotid secretory protein, and salivary amylase are the major secretory proteins of mouse parotid gland where they appear in a constant ratio. Here we describe the isolation of the PSP gene and show through expression analysis on this and the salivary amylase gene that the two genes are transcribed in a coordinate fashion in adult animals, whereas the activation profiles are different during postnatal development. An explanation is put forward that involves activation of the genes at different stages of the acinar cell differentiation, leading in adults to the maximal and thus proportionate expression.

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Year:  1986        PMID: 2428613      PMCID: PMC1167055          DOI: 10.1002/j.1460-2075.1986.tb04441.x

Source DB:  PubMed          Journal:  EMBO J        ISSN: 0261-4189            Impact factor:   11.598


  38 in total

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Authors:  J P Hjorth
Journal:  Biochem Genet       Date:  1979-08       Impact factor: 1.890

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Journal:  Genetics       Date:  1980-05       Impact factor: 4.562

4.  Tissue-specific expression of mouse alpha-amylase genes.

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Authors:  R A Young; O Hagenbüchle; U Schibler
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6.  3'-terminal nucleotide sequence of encephalomyocarditis virus RNA determined by reverse transcriptase and chain-terminating inhibitors.

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7.  Regulation of metallothionein--thymidine kinase fusion plasmids injected into mouse eggs.

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  9 in total

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4.  Novel salivary gland specific binding elements located in the PSP proximal enhancer core.

Authors:  P Svendsen; J Laursen; H Krogh-Pedersen; J P Hjorth
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8.  Characterization of human and rat immortalized clones parotid acinar cells with respect to specific proteins and their mRNAs, and receptor-linked adenylate cyclase.

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Journal:  In Vitro Cell Dev Biol Anim       Date:  1995-11       Impact factor: 2.416

9.  High-level salivary gland expression in transgenic mice.

Authors:  H J Larsen; C H Brodersen; J P Hjorth
Journal:  Transgenic Res       Date:  1994-09       Impact factor: 2.788

  9 in total

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