Literature DB >> 24279751

Two new phthalides with BuChE inhibitory activity from Ligusticum chuanxiong.

Jian Huang1, Xiao-Qing Lu, Jin Lu, Guo-Yu Li, Hang-Yu Wang, Li-Hong Li, Rui-Chao Lin, Jin-Hui Wang.   

Abstract

Two new phthalides, chuanxiongdiolides A and B, were isolated from the roots of Ligusticum chuanxiong Hort. Their structures were established by UV, IR, 1D (¹H, ¹³C) and 2D (HSQC, ¹H-¹H COSY, HMBC, NOESY) NMR, and HR-ESI-MS methods, and their absolute configurations were assigned via circular dichroism exciton chirality. The two compounds showed different degrees of inhibitory effects against butyrylcholine esterase.

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Year:  2013        PMID: 24279751     DOI: 10.1080/10286020.2013.825610

Source DB:  PubMed          Journal:  J Asian Nat Prod Res        ISSN: 1028-6020            Impact factor:   1.569


  4 in total

1.  Fingerprint analysis of processed Rhizoma Chuanxiong by high-performance liquid chromatography coupled with diode array detection.

Authors:  Jia-Yan Fang; Lin Zhu; Tao Yi; Jian-Ye Zhang; Ling Yi; Zhi-Tao Liang; Li Xia; Jia-Fu Feng; Jun Xu; Yi-Na Tang; Zhong-Zhen Zhao; Hu-Biao Chen
Journal:  Chin Med       Date:  2015-02-10       Impact factor: 5.455

2.  Novel phthalide derivatives identified from Ligusticum chuanxiong (Chuanxiong).

Authors:  Jun Yang; Xiao-Lin Feng; Yang Yu; Qi Wang; Jian Zou; Chuan-Xi Wang; Zhen-Qiang Mu; Xin-Sheng Yao; Hao Gao
Journal:  Chin Med       Date:  2016-03-08       Impact factor: 5.455

3.  Bioactive thionic compounds and aromatic glycosides from Ligusticum chuanxiong.

Authors:  Xu Zhang; Bing Han; Ziming Feng; Jianshuang Jiang; Yanan Yang; Peicheng Zhang
Journal:  Acta Pharm Sin B       Date:  2018-04-11       Impact factor: 11.413

Review 4.  Recent progress on the traditional Chinese medicines that regulate the blood.

Authors:  Hsin-Yi Hung; Tian-Shung Wu
Journal:  J Food Drug Anal       Date:  2016-01-05       Impact factor: 6.157

  4 in total

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