Literature DB >> 24273588

Personalized screening for cancers: should we consider polygenic profiling?

Nora Pashayan1, Qi Guo, Paul D P Pharoah.   

Abstract

Polygenic profiling and risk stratification for population-based screening for cancer improve the efficiency of the screening programs. Translation of genomics into personalized screening programs requires evidence from empirical research on the balance of benefits and harms of personalized screening, and engagement with the public, professionals and policy makers.

Entities:  

Keywords:  Polygenic profiling; cancer; personalized screening

Year:  2013        PMID： 24273588      PMCID： PMC3837202          DOI： 10.2217/pme.13.46

Source DB:  PubMed          Journal:  Per Med        ISSN： 1741-0541            Impact factor:   2.512


  14 in total

1.  Polygenic susceptibility to breast cancer and implications for prevention.

Authors:  Paul D P Pharoah; Antonis Antoniou; Martin Bobrow; Ron L Zimmern; Douglas F Easton; Bruce A J Ponder
Journal:  Nat Genet       Date:  2002-03-04       Impact factor: 38.330

Review 2.  Genome-based prediction of breast cancer risk in the general population: a modeling study based on meta-analyses of genetic associations.

Authors:  Moniek van Zitteren; Jeroen B van der Net; Suman Kundu; Andrew N Freedman; Cornelia M van Duijn; A Cecile J W Janssens
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2011-01       Impact factor: 4.254

3.  Polygenes, risk prediction, and targeted prevention of breast cancer.

Authors:  Paul D P Pharoah; Antonis C Antoniou; Douglas F Easton; Bruce A J Ponder
Journal:  N Engl J Med       Date:  2008-06-26       Impact factor: 91.245

4.  Translating genomics into improved population screening: hype or hope?

Authors:  Nora Pashayan; Paul Pharoah
Journal:  Hum Genet       Date:  2011-04-12       Impact factor: 4.132

5.  iCOGS collection provides a collaborative model. Foreword.

Authors:  Orli G Bahcall
Journal:  Nat Genet       Date:  2013-04       Impact factor: 38.330

6.  Public health implications from COGS and potential for risk stratification and screening.

Authors:  Hilary Burton; Susmita Chowdhury; Tom Dent; Alison Hall; Nora Pashayan; Paul Pharoah
Journal:  Nat Genet       Date:  2013-04       Impact factor: 38.330

7.  Cancer risks in BRCA2 mutation carriers.

Authors: 
Journal:  J Natl Cancer Inst       Date:  1999-08-04       Impact factor: 13.506

Review 8.  Building the evidence base for decision making in cancer genomic medicine using comparative effectiveness research.

Authors:  Katrina A B Goddard; William A Knaus; Evelyn Whitlock; Gary H Lyman; Heather Spencer Feigelson; Sheri D Schully; Scott Ramsey; Sean Tunis; Andrew N Freedman; Muin J Khoury; David L Veenstra
Journal:  Genet Med       Date:  2012-07       Impact factor: 8.822

9.  Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.

Authors:  Rosalind A Eeles; Ali Amin Al Olama; Sara Benlloch; Edward J Saunders; Daniel A Leongamornlert; Malgorzata Tymrakiewicz; Maya Ghoussaini; Craig Luccarini; Joe Dennis; Sarah Jugurnauth-Little; Tokhir Dadaev; David E Neal; Freddie C Hamdy; Jenny L Donovan; Ken Muir; Graham G Giles; Gianluca Severi; Fredrik Wiklund; Henrik Gronberg; Christopher A Haiman; Fredrick Schumacher; Brian E Henderson; Loic Le Marchand; Sara Lindstrom; Peter Kraft; David J Hunter; Susan Gapstur; Stephen J Chanock; Sonja I Berndt; Demetrius Albanes; Gerald Andriole; Johanna Schleutker; Maren Weischer; Federico Canzian; Elio Riboli; Tim J Key; Ruth C Travis; Daniele Campa; Sue A Ingles; Esther M John; Richard B Hayes; Paul D P Pharoah; Nora Pashayan; Kay-Tee Khaw; Janet L Stanford; Elaine A Ostrander; Lisa B Signorello; Stephen N Thibodeau; Dan Schaid; Christiane Maier; Walther Vogel; Adam S Kibel; Cezary Cybulski; Jan Lubinski; Lisa Cannon-Albright; Hermann Brenner; Jong Y Park; Radka Kaneva; Jyotsna Batra; Amanda B Spurdle; Judith A Clements; Manuel R Teixeira; Ed Dicks; Andrew Lee; Alison M Dunning; Caroline Baynes; Don Conroy; Melanie J Maranian; Shahana Ahmed; Koveela Govindasami; Michelle Guy; Rosemary A Wilkinson; Emma J Sawyer; Angela Morgan; David P Dearnaley; Alan Horwich; Robert A Huddart; Vincent S Khoo; Christopher C Parker; Nicholas J Van As; Christopher J Woodhouse; Alan Thompson; Tim Dudderidge; Chris Ogden; Colin S Cooper; Artitaya Lophatananon; Angela Cox; Melissa C Southey; John L Hopper; Dallas R English; Markus Aly; Jan Adolfsson; Jiangfeng Xu; Siqun L Zheng; Meredith Yeager; Rudolf Kaaks; W Ryan Diver; Mia M Gaudet; Mariana C Stern; Roman Corral; Amit D Joshi; Ahva Shahabi; Tiina Wahlfors; Teuvo L J Tammela; Anssi Auvinen; Jarmo Virtamo; Peter Klarskov; Børge G Nordestgaard; M Andreas Røder; Sune F Nielsen; Stig E Bojesen; Afshan Siddiq; Liesel M Fitzgerald; Suzanne Kolb; Erika M Kwon; Danielle M Karyadi; William J Blot; Wei Zheng; Qiuyin Cai; Shannon K McDonnell; Antje E Rinckleb; Bettina Drake; Graham Colditz; Dominika Wokolorczyk; Robert A Stephenson; Craig Teerlink; Heiko Muller; Dietrich Rothenbacher; Thomas A Sellers; Hui-Yi Lin; Chavdar Slavov; Vanio Mitev; Felicity Lose; Srilakshmi Srinivasan; Sofia Maia; Paula Paulo; Ethan Lange; Kathleen A Cooney; Antonis C Antoniou; Daniel Vincent; François Bacot; Daniel C Tessier; Zsofia Kote-Jarai; Douglas F Easton
Journal:  Nat Genet       Date:  2013-04       Impact factor: 38.330

10.  GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.

Authors:  Paul D P Pharoah; Ya-Yu Tsai; Susan J Ramus; Catherine M Phelan; Ellen L Goode; Kate Lawrenson; Melissa Buckley; Brooke L Fridley; Jonathan P Tyrer; Howard Shen; Rachel Weber; Rod Karevan; Melissa C Larson; Honglin Song; Daniel C Tessier; François Bacot; Daniel Vincent; Julie M Cunningham; Joe Dennis; Ed Dicks; Katja K Aben; Hoda Anton-Culver; Natalia Antonenkova; Sebastian M Armasu; Laura Baglietto; Elisa V Bandera; Matthias W Beckmann; Michael J Birrer; Greg Bloom; Natalia Bogdanova; James D Brenton; Louise A Brinton; Angela Brooks-Wilson; Robert Brown; Ralf Butzow; Ian Campbell; Michael E Carney; Renato S Carvalho; Jenny Chang-Claude; Y Anne Chen; Zhihua Chen; Wong-Ho Chow; Mine S Cicek; Gerhard Coetzee; Linda S Cook; Daniel W Cramer; Cezary Cybulski; Agnieszka Dansonka-Mieszkowska; Evelyn Despierre; Jennifer A Doherty; Thilo Dörk; Andreas du Bois; Matthias Dürst; Diana Eccles; Robert Edwards; Arif B Ekici; Peter A Fasching; David Fenstermacher; James Flanagan; Yu-Tang Gao; Montserrat Garcia-Closas; Aleksandra Gentry-Maharaj; Graham Giles; Anxhela Gjyshi; Martin Gore; Jacek Gronwald; Qi Guo; Mari K Halle; Philipp Harter; Alexander Hein; Florian Heitz; Peter Hillemanns; Maureen Hoatlin; Estrid Høgdall; Claus K Høgdall; Satoyo Hosono; Anna Jakubowska; Allan Jensen; Kimberly R Kalli; Beth Y Karlan; Linda E Kelemen; Lambertus A Kiemeney; Susanne Krüger Kjaer; Gottfried E Konecny; Camilla Krakstad; Jolanta Kupryjanczyk; Diether Lambrechts; Sandrina Lambrechts; Nhu D Le; Nathan Lee; Janet Lee; Arto Leminen; Boon Kiong Lim; Jolanta Lissowska; Jan Lubiński; Lene Lundvall; Galina Lurie; Leon F A G Massuger; Keitaro Matsuo; Valerie McGuire; John R McLaughlin; Usha Menon; Francesmary Modugno; Kirsten B Moysich; Toru Nakanishi; Steven A Narod; Roberta B Ness; Heli Nevanlinna; Stefan Nickels; Houtan Noushmehr; Kunle Odunsi; Sara Olson; Irene Orlow; James Paul; Tanja Pejovic; Liisa M Pelttari; Jenny Permuth-Wey; Malcolm C Pike; Elizabeth M Poole; Xiaotao Qu; Harvey A Risch; Lorna Rodriguez-Rodriguez; Mary Anne Rossing; Anja Rudolph; Ingo Runnebaum; Iwona K Rzepecka; Helga B Salvesen; Ira Schwaab; Gianluca Severi; Hui Shen; Vijayalakshmi Shridhar; Xiao-Ou Shu; Weiva Sieh; Melissa C Southey; Paul Spellman; Kazuo Tajima; Soo-Hwang Teo; Kathryn L Terry; Pamela J Thompson; Agnieszka Timorek; Shelley S Tworoger; Anne M van Altena; David van den Berg; Ignace Vergote; Robert A Vierkant; Allison F Vitonis; Shan Wang-Gohrke; Nicolas Wentzensen; Alice S Whittemore; Elisabeth Wik; Boris Winterhoff; Yin Ling Woo; Anna H Wu; Hannah P Yang; Wei Zheng; Argyrios Ziogas; Famida Zulkifli; Marc T Goodman; Per Hall; Douglas F Easton; Celeste L Pearce; Andrew Berchuck; Georgia Chenevix-Trench; Edwin Iversen; Alvaro N A Monteiro; Simon A Gayther; Joellen M Schildkraut; Thomas A Sellers
Journal:  Nat Genet       Date:  2013-04       Impact factor: 38.330
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  8 in total

1.  Extended mortality results for ovarian cancer screening in the PLCO trial with median 15years follow-up.

Authors:  Paul F Pinsky; Kelly Yu; Barnett S Kramer; Amanda Black; Saundra S Buys; Edward Partridge; John Gohagan; Christine D Berg; Philip C Prorok
Journal:  Gynecol Oncol       Date:  2016-09-09       Impact factor: 5.482

2.  Adjusting the frequency of mammography screening on the basis of genetic risk: Attitudes among women in the UK.

Authors:  Susanne F Meisel; Nora Pashayan; Belinda Rahman; Lucy Side; Lindsay Fraser; Sue Gessler; Anne Lanceley; Jane Wardle
Journal:  Breast       Date:  2015-02-21       Impact factor: 4.380

3.  Implications of polygenic risk-stratified screening for prostate cancer on overdiagnosis.

Authors:  Nora Pashayan; Stephen W Duffy; David E Neal; Freddie C Hamdy; Jenny L Donovan; Richard M Martin; Patricia Harrington; Sara Benlloch; Ali Amin Al Olama; Mitul Shah; Zsofia Kote-Jarai; Douglas F Easton; Rosalind Eeles; Paul D Pharoah
Journal:  Genet Med       Date:  2015-01-08       Impact factor: 8.822

Review 4.  An epidemiological perspective of personalized medicine: the Estonian experience.

Authors:  L Milani; L Leitsalu; A Metspalu
Journal:  J Intern Med       Date:  2015-02       Impact factor: 8.989

Review 5.  Cancer prevention: state of the art and future prospects.

Authors:  I Valle; D Tramalloni; N L Bragazzi
Journal:  J Prev Med Hyg       Date:  2015-06-10

6.  Prevention in the age of personal responsibility: epigenetic risk-predictive screening for female cancers as a case study.

Authors:  Ineke Bolt; Eline M Bunnik; Krista Tromp; Nora Pashayan; Martin Widschwendter; Inez de Beaufort
Journal:  J Med Ethics       Date:  2020-11-18       Impact factor: 2.903

7.  Independent evaluation of melanoma polygenic risk scores in UK and Australian prospective cohorts.

Authors:  Julia Steinberg; Mark M Iles; Jin Yee Lee; Xiaochuan Wang; Matthew H Law; Amelia K Smit; Tu Nguyen-Dumont; Graham G Giles; Melissa C Southey; Roger L Milne; Graham J Mann; D Timothy Bishop; Robert J MacInnis; Anne E Cust
Journal:  Br J Dermatol       Date:  2022-03-31       Impact factor: 11.113

8.  Constructing Hypothetical Risk Data from the Area under the ROC Curve: Modelling Distributions of Polygenic Risk.

Authors:  Suman Kundu; Jannigje G Kers; A Cecile J W Janssens
Journal:  PLoS One       Date:  2016-03-29       Impact factor: 3.240
  8 in total

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