Literature DB >> 24267605

Anorectal physiology and pathophysiology in the elderly.

Siegfried W B Yu1, Satish S C Rao.   

Abstract

Anorectal medical disorders facing the elderly include fecal incontinence, fecal impaction with overflow fecal incontinence, chronic constipation, dyssynergic defecation, hemorrhoids, anal fissure, and pelvic floor disorders. This article discusses the latest advances in age-related changes in morphology and function of anal sphincter, changes in cellular and molecular biology, alterations in neurotransmitters and reflexes, and their impact on functional changes of the anorectum in the elderly. These biophysiologic changes have implications for the pathophysiology of anorectal disorders. A clear understanding and working knowledge of the functional anatomy and pathophysiology will enable appropriate diagnosis and treatment of these disorders.
Copyright © 2014 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Age-related cellular dysfunction; Anorectal pathophysiology; Constipation; Elderly; Fecal incontinence

Mesh：

Year:  2014        PMID： 24267605      PMCID： PMC3910254          DOI： 10.1016/j.cger.2013.10.003

Source DB:  PubMed          Journal:  Clin Geriatr Med        ISSN： 0749-0690            Impact factor:   3.076


  44 in total

1.  Frequency and determinants of urgent requests to home care agencies for community-dwelling elderly.

Authors:  Brigitte Santos-Eggimann; Nicole Chavaz Cirilli; Jean-Jacques Monachon
Journal:  Home Health Care Serv Q       Date:  2003

2.  Diagnosis and management of fecal incontinence. American College of Gastroenterology Practice Parameters Committee.

Authors:  Satish S C Rao
Journal:  Am J Gastroenterol       Date:  2004-08       Impact factor: 10.864

3.  Prolonged anorectal manometry and external anal sphincter electromyography in ambulant human subjects.

Authors:  D Kumar; D Waldron; N S Williams; C Browning; M R Hutton; D L Wingate
Journal:  Dig Dis Sci       Date:  1990-05       Impact factor: 3.199

4.  Inhibitory neuropeptides and intrinsic inhibitory innervation of descending human colon.

Authors:  T R Koch; J A Carney; V L Go; J H Szurszewski
Journal:  Dig Dis Sci       Date:  1991-06       Impact factor: 3.199

5.  Relationship between anal canal tone and rectal motor activity.

Authors:  A Ferrara; J H Pemberton; K E Levin; R B Hanson
Journal:  Dis Colon Rectum       Date:  1993-04       Impact factor: 4.585

6.  Changes in calcium channel current densities in rat colonic smooth muscle cells during development and aging.

Authors:  Z Xiong; N Sperelakis; A Noffsinger; C Fenoglio-Preiser
Journal:  Am J Physiol       Date:  1993-09

7.  Ambulatory 24-h colonic manometry in healthy humans.

Authors:  S S Rao; P Sadeghi; J Beaty; R Kavlock; K Ackerson
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2001-04       Impact factor: 4.052

Review 8.  Gastrointestinal motility problems in the elderly patient.

Authors:  Michael Firth; Charlene M Prather
Journal:  Gastroenterology       Date:  2002-05       Impact factor: 22.682

Review 9.  Aging and neural control of the GI tract. I. Age-related changes in the enteric nervous system.

Authors:  Paul R Wade
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2002-09       Impact factor: 4.052

10.  Age-related changes in the morphology of the myenteric plexus of the human colon.

Authors:  Menachem Hanani; Yakov Fellig; Raphael Udassin; Herbert R Freund
Journal:  Auton Neurosci       Date:  2004-06-30       Impact factor: 3.145
View more
  19 in total

1.  My Approach to Fecal Incontinence: It's all about Consistency (Stool, that is).

Authors:  Stacy B Menees
Journal:  Am J Gastroenterol       Date:  2017-06-20       Impact factor: 10.864

2.  The diagnostic value of a digital rectal examination compared with high-resolution anorectal manometry in patients with chronic constipation and fecal incontinence.

Authors:  Jae Seung Soh; Hyo Jeong Lee; Kee Wook Jung; In Ja Yoon; Hyun Sook Koo; So Young Seo; Seohyun Lee; Jung Ho Bae; Ho-Su Lee; Sang Hyoung Park; Dong-Hoon Yang; Kyung-Jo Kim; Byong Duk Ye; Jeong-Sik Byeon; Suk-Kyun Yang; Jin-Ho Kim; Seung-Jae Myung
Journal:  Am J Gastroenterol       Date:  2015-06-02       Impact factor: 10.864

Review 3.  Intractable Constipation in the Elderly.

Authors:  Noemi Baffy; Amy E Foxx-Orenstein; Lucinda A Harris; Susan Sterler
Journal:  Curr Treat Options Gastroenterol       Date:  2017-09

4.  Induction Chemotherapy Reduces Patient-reported Toxicities During Neoadjuvant Chemoradiation with Intensity Modulated Radiotherapy for Rectal Cancer.

Authors:  Shu Y Ng; Kathryn L Colborn; Lajhem Cambridge; Andrea Cercek; Diane L Reidy-Lagunes; Neil Segal; Zsofia Stadler; Leonard B Saltz; Philip B Paty; Jose Guillem; Martin R Weiser; Garrett Nash; Julio Garcia-Aguilar; Karyn A Goodman
Journal:  Clin Colorectal Cancer       Date:  2019-04-06       Impact factor: 4.481

Review 5.  [Motility disorders of the colon].

Authors:  S Müller-Lissner
Journal:  Internist (Berl)       Date:  2015-06       Impact factor: 0.743

6.  Clinical Challenges of Fecal Incontinence in the Elderly.

Authors:  Hadie Razjouyan; Shanti Prasad; Sita Chokhavatia
Journal:  Curr Treat Options Gastroenterol       Date:  2015-09

7.  Fecal Incontinence Symptoms and Impact in Older Versus Younger Women Seeking Care.

Authors:  Isuzu Meyer; Christina T Blanchard; Alayne D Markland; Elena G Gibson; Holly E Richter
Journal:  Dis Colon Rectum       Date:  2019-06       Impact factor: 4.585

8.  Outcome of bowel function following anterior resection for rectal cancer-an analysis using the low anterior resection syndrome (LARS) score.

Authors:  Juliane Kupsch; Thomas Jackisch; Klaus E Matzel; Joerg Zimmer; Andreas Schreiber; Anja Sims; Helmut Witzigmann; Sigmar Stelzner
Journal:  Int J Colorectal Dis       Date:  2018-03-15       Impact factor: 2.571

9.  Fatigability of the external anal sphincter muscles using a novel strength training resistance exercise device.

Authors:  Ling Mei; Krupa Patel; Navjit Lehal; Mark K Kern; Adam Benjamin; Patrick Sanvanson; Reza Shaker
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2021-02-17       Impact factor: 4.052

Review 10.  Epidemiology and management of chronic constipation in elderly patients.

Authors:  Maria Vazquez Roque; Ernest P Bouras
Journal:  Clin Interv Aging       Date:  2015-06-02       Impact factor: 4.458
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.