Literature DB >> 12016432

Gastrointestinal motility problems in the elderly patient.

Michael Firth1, Charlene M Prather.   

Abstract

Statistics abound demonstrating the aging of the population, and this comes as no news to physicians caring for an increasing number of elderly patients. This group experiences the expected age-related physiologic declines, including systems critical to integrative functions such as immunologic, neurologic, and metabolic systems. Although an increased prevalence of several common gastrointestinal disorders occurs in the elderly person, aging per se appears to have less direct effect on most gastrointestinal functions, in large part because of the functional reserve of the gastrointestinal tract. Although irritable bowel symptoms decrease with aging, there seems to be an increase in many gastrointestinal disorders of function and motility. The gastroenterologist will frequently encounter elderly patients with complaints of dysphagia, anorexia, dyspepsia, and disorders of colonic function. Understanding age-related changes in gastrointestinal physiology and effects of common comorbid illnesses enhances the ability to evaluate and treat these common, troublesome symptoms.

Entities:  

Mesh:

Year:  2002        PMID: 12016432     DOI: 10.1053/gast.2002.33566

Source DB:  PubMed          Journal:  Gastroenterology        ISSN: 0016-5085            Impact factor:   22.682


  22 in total

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2.  Cancer constipation: are opioids really the culprit?

Authors:  Mellar P Davis
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3.  Evidence that stimulation of ghrelin receptors in the spinal cord initiates propulsive activity in the colon of the rat.

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Journal:  J Physiol       Date:  2006-07-27       Impact factor: 5.182

4.  Lower esophageal sphincter relaxation is impaired in older patients with dysphagia.

Authors:  Laura K Besanko; Carly M Burgstad; Reme Mountifield; Jane M Andrews; Richard Heddle; Helen Checklin; Robert J L Fraser
Journal:  World J Gastroenterol       Date:  2011-03-14       Impact factor: 5.742

5.  Relative Risk of Adverse Events and Treatment Discontinuations Between Older and Non-Older Adults Treated with Antimuscarinics for Overactive Bladder: A Systematic Review and Meta-Analysis.

Authors:  Silken A Usmani; Kristine Reckenberg; Olivia Johnson; Paul M Stranges; Besu F Teshome; Clark D Kebodeaux; Scott Martin Vouri
Journal:  Drugs Aging       Date:  2019-07       Impact factor: 3.923

6.  [Chronic motility disorders of the upper gastrointestinal tract in the elderly. Pharmaceutical, endoscopic and operative therapy].

Authors:  J-U Sonne; J F Erckenbrecht
Journal:  Internist (Berl)       Date:  2014-07       Impact factor: 0.743

7.  Treatment of epilepsy in the elderly.

Authors:  Ilo E Leppik
Journal:  Curr Treat Options Neurol       Date:  2008-07       Impact factor: 3.598

8.  Aging-associated oxidative stress leads to decrease in IAS tone via RhoA/ROCK downregulation.

Authors:  Jagmohan Singh; Sumit Kumar; Chadalavada Vijay Krishna; Satish Rattan
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2014-04-17       Impact factor: 4.052

9.  Age-related changes in functional NANC innervation with VIP and substance P in the jejunum of Lewis rats.

Authors:  Michael S Kasparek; Javairiah Fatima; Corey W Iqbal; Judith A Duenes; Michael G Sarr
Journal:  Auton Neurosci       Date:  2009-09-05       Impact factor: 3.145

Review 10.  Anorectal physiology and pathophysiology in the elderly.

Authors:  Siegfried W B Yu; Satish S C Rao
Journal:  Clin Geriatr Med       Date:  2014-02       Impact factor: 3.076

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