Literature DB >> 24262382

Access to renal transplantation for the elderly in the face of new allocation policy: a review of contemporary perspectives on "older" issues.

Paul L Tso1.   

Abstract

The benefits of renal transplantation have been demonstrated to extend to the elderly. As a result, more seniors have been placed on the kidney transplant wait list and have received renal allografts in recent years. In June 2013 significant amendments to deceased donor kidney allocation policy were approved to be instituted in 2014 with the goal of increasing overall life years and graft years achieved compared to the current system. Going forward, it is conceivable that transplant centers may perceive a need to adjust practice patterns and modify evaluation and listing criteria for the elderly as the proportion of kidneys distributed to this segment of the wait list would potentially decrease under the new system, further increasing wait times. This review examines contemporary perspectives on access to transplantation for seniors and pertinent issues for this subgroup such as wait time, comorbidity, and evaluation and listing practices. Potential approaches to improve the evaluation of elderly patients being considered for transplant and to increase availability of expanded criteria donor (or higher kidney donor profile index) and living donor organ transplant opportunities while maintaining acceptable outcomes for seniors are explored.
© 2013.

Entities:  

Mesh:

Year:  2013        PMID: 24262382     DOI: 10.1016/j.trre.2013.10.002

Source DB:  PubMed          Journal:  Transplant Rev (Orlando)        ISSN: 0955-470X            Impact factor:   3.943


  11 in total

1.  The Kidney Donor Profile Index (KDPI) of marginal donors allocated by standardized pretransplant donor biopsy assessment: distribution and association with graft outcomes.

Authors:  I Gandolfini; C Buzio; P Zanelli; A Palmisano; E Cremaschi; A Vaglio; G Piotti; L Melfa; G La Manna; G Feliciangeli; M Cappuccilli; M P Scolari; I Capelli; L Panicali; O Baraldi; S Stefoni; A Buscaroli; L Ridolfi; A D'Errico; G Cappelli; D Bonucchi; E Rubbiani; A Albertazzi; A Mehrotra; P Cravedi; U Maggiore
Journal:  Am J Transplant       Date:  2014-08-25       Impact factor: 8.086

2.  Risk of ESKD in Older Live Kidney Donors with Hypertension.

Authors:  Fawaz Al Ammary; Xun Luo; Abimereki D Muzaale; Allan B Massie; Deidra C Crews; Madeleine M Waldram; Mohamud A Qadi; Jacqueline Garonzik-Wang; Macey L Henderson; Daniel C Brennan; Alexander C Wiseman; Richard C Lindrooth; Jon J Snyder; Josef Coresh; Dorry L Segev
Journal:  Clin J Am Soc Nephrol       Date:  2019-06-25       Impact factor: 8.237

Review 3.  Immunosenescence in renal transplantation: a changing balance of innate and adaptive immunity.

Authors:  Midas Seyda; Markus Quante; Hirofumi Uehara; Bendix R Slegtenhorst; Abdala Elkhal; Stefan G Tullius
Journal:  Curr Opin Organ Transplant       Date:  2015-08       Impact factor: 2.640

4.  Relationship between pre-transplant physical function and outcomes after kidney transplant.

Authors:  Elizabeth C Lorenz; Andrea L Cheville; Hatem Amer; Brian R Kotajarvi; Mark D Stegall; Tanya M Petterson; Walter K Kremers; Fernando G Cosio; Nathan K LeBrasseur
Journal:  Clin Transplant       Date:  2017-04-17       Impact factor: 2.863

5.  Protocolized exercise improves frailty parameters and lower extremity impairment: A promising prehabilitation strategy for kidney transplant candidates.

Authors:  Elizabeth C Lorenz; LaTonya J Hickson; Renee M Weatherly; Karin L Thompson; Heidi A Walker; Judy M Rasmussen; Tara L Stewart; James K Garrett; Hatem Amer; Cassie C Kennedy
Journal:  Clin Transplant       Date:  2020-07-24       Impact factor: 2.863

Review 6.  Therapeutic alternatives and palliative care for advanced renal disease in the very elderly: a review of the literature.

Authors:  Carlos G Musso; Konstantina Trigka; Periklis Dousdampanis; Jose Jauregui
Journal:  Int Urol Nephrol       Date:  2014-12-05       Impact factor: 2.370

Review 7.  [Kidney transplantation in old age].

Authors:  C Kurschat
Journal:  Z Gerontol Geriatr       Date:  2016-07-27       Impact factor: 1.281

8.  Utility of Applying Quality Assessment Tools for Kidneys With KDPI ≥80.

Authors:  Mona D Doshi; Peter P Reese; Isaac E Hall; Bernd Schröppel; Joseph Ficek; Richard N Formica; Francis L Weng; Rick D Hasz; Heather Thiessen-Philbrook; Chirag R Parikh
Journal:  Transplantation       Date:  2017-06       Impact factor: 4.939

9.  Changes in Discard Rate After the Introduction of the Kidney Donor Profile Index (KDPI).

Authors:  S Bae; A B Massie; X Luo; S Anjum; N M Desai; D L Segev
Journal:  Am J Transplant       Date:  2016-03-22       Impact factor: 8.086

Review 10.  Strategies to increase the donor pool and access to kidney transplantation: an international perspective.

Authors:  Umberto Maggiore; Rainer Oberbauer; Julio Pascual; Ondrej Viklicky; Chris Dudley; Klemens Budde; Soren Schwartz Sorensen; Marc Hazzan; Marian Klinger; Daniel Abramowicz
Journal:  Nephrol Dial Transplant       Date:  2014-06-06       Impact factor: 5.992

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