Literature DB >> 27464740

[Kidney transplantation in old age].

C Kurschat1.   

Abstract

Older patients clearly benefit from a kidney transplantation despite multiple comorbidities and complications, particularly with respect to life expectancy. Older patients remaining on dialysis on average die earlier compared to patients who underwent a kidney transplantation. In addition, patients experience a significant increase in the quality of life after renal transplantation. However, every patient has to be thoroughly evaluated to assess the individual benefits of a renal transplantation. Geriatric tools are particularly helpful to evaluate the suitability of older individuals. In 1999 the Eurotransplant senior program (ESP or "old for old") was initiated, aiming at shortening waiting time and cold ischemia time for patients on the waiting list. In this program, kidneys of donors aged 65 years and older are locally allocated to recipients also of 65 years and older. The results in ESP are promising, to the effect that this program helps older patients to receive a kidney transplant earlier than by the normal procedure; however, a better alternative to the ESP program is living donor transplantation, provided that a suitable donor is available. There is no age limit for the evaluation of potential donors. Compared to deceased donor kidney transplantation a living donor kidney will most likely function with a higher spontaneous rate and for a longer period of time and therefore provides a clear advantage for older recipients.

Entities:  

Keywords:  Aging; Eurotransplant senior program; Renal replacement therapy; Survival; Transplant function

Mesh:

Year:  2016        PMID: 27464740     DOI: 10.1007/s00391-016-1118-x

Source DB:  PubMed          Journal:  Z Gerontol Geriatr        ISSN: 0948-6704            Impact factor:   1.281


  39 in total

1.  Age and the associations of living donor and expanded criteria donor kidneys with kidney transplant outcomes.

Authors:  Miklos Z Molnar; Elani Streja; Csaba P Kovesdy; Anuja Shah; Edmund Huang; Suphamai Bunnapradist; Mahesh Krishnan; Joel D Kopple; Kamyar Kalantar-Zadeh
Journal:  Am J Kidney Dis       Date:  2012-02-04       Impact factor: 8.860

2.  Incidence and Long-Term Prognosis of Cancer After Kidney Transplantation.

Authors:  V Pendón-Ruiz de Mier; M D Navarro Cabello; S Martínez Vaquera; M Lopez-Andreu; M L Aguera Morales; A Rodriguez-Benot; P Aljama Garcia
Journal:  Transplant Proc       Date:  2015-11       Impact factor: 1.066

Review 3.  Rethinking chronic allograft nephropathy: the concept of accelerated senescence.

Authors:  P F Halloran; A Melk; C Barth
Journal:  J Am Soc Nephrol       Date:  1999-01       Impact factor: 10.121

4.  Survival of patients who have been on a waiting list for renal transplantation.

Authors:  C Medin; C G Elinder; B Hylander; B Blom; H Wilczek
Journal:  Nephrol Dial Transplant       Date:  2000-05       Impact factor: 5.992

5.  Frailty in older adults: evidence for a phenotype.

Authors:  L P Fried; C M Tangen; J Walston; A B Newman; C Hirsch; J Gottdiener; T Seeman; R Tracy; W J Kop; G Burke; M A McBurnie
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2001-03       Impact factor: 6.053

6.  Early mortality rates in older kidney recipients with comorbid risk factors.

Authors:  H Myron Kauffman; Maureen A McBride; Cynthia S Cors; Allan M Roza; James J Wynn
Journal:  Transplantation       Date:  2007-02-27       Impact factor: 4.939

Review 7.  Acceptability of older adults as living kidney donors.

Authors:  Ngan N Lam; Amit X Garg
Journal:  Curr Opin Nephrol Hypertens       Date:  2016-05       Impact factor: 2.894

Review 8.  Access to renal transplantation for the elderly in the face of new allocation policy: a review of contemporary perspectives on "older" issues.

Authors:  Paul L Tso
Journal:  Transplant Rev (Orlando)       Date:  2013-10-10       Impact factor: 3.943

9.  Outcomes of kidney transplantation from older living donors to older recipients.

Authors:  Jagbir Gill; Suphamai Bunnapradist; Gabriel M Danovitch; David Gjertson; John S Gill; Michael Cecka
Journal:  Am J Kidney Dis       Date:  2008-07-24       Impact factor: 8.860

10.  Geriatric comorbidities, such as falls, confer an independent mortality risk to elderly dialysis patients.

Authors:  Marilyn Li; George Tomlinson; Gary Naglie; Wendy L Cook; Sarbjit Vanita Jassal
Journal:  Nephrol Dial Transplant       Date:  2007-12-05       Impact factor: 5.992

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  2 in total

Review 1.  The emerging role of cellular senescence in renal diseases.

Authors:  Bingru Zhou; Ying Wan; Rong Chen; Chunmei Zhang; Xuesen Li; Fanyin Meng; Shannon Glaser; Nan Wu; Tianhao Zhou; Siwen Li; Heather Francis; Gianfranco Alpini; Ping Zou
Journal:  J Cell Mol Med       Date:  2020-01-08       Impact factor: 5.310

2.  Prognostic Signature of Chronic Kidney Disease in Advanced Age: Secondary Analysis from the InGAH Study with One-Year Follow-Up.

Authors:  Anna Maria Meyer; Lena Pickert; Annika Heeß; Ingrid Becker; Christine Kurschat; Malte P Bartram; Thomas Benzing; Maria Cristina Polidori
Journal:  Biomolecules       Date:  2022-03-09
  2 in total

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