Literature DB >> 24242633

Offering predictive testing for Huntington disease in a medical genetics clinic: Practical applications.

R L Bennett1, T D Bird, L Teri.   

Abstract

Predictive testing for Huntington disease is presently offered in a select few medical genetics centers in the United States. This is in part due to the labor intensive counseling and psychological testing suggested by the research protocols. We discuss some specific suggestions for establishing programs for Huntington disease predictive testing within pre-existing medical genetics clinics to encourage more centers to offer presymptomatic testing. This will allow more at risk individuals the opportunity to consider predictive testing and cut down the expenses of traveling to the few predictive testing centers that currently exist. The counseling principals will remain similar to those discussed here, even following the identification of the Huntington disease mutation.

Entities:  

Year:  1993        PMID: 24242633     DOI: 10.1007/BF00962073

Source DB:  PubMed          Journal:  J Genet Couns        ISSN: 1059-7700            Impact factor:   2.537


  14 in total

1.  Genetic testing for Huntington's disease--a family issue.

Authors:  C V Hayes
Journal:  N Engl J Med       Date:  1992-11-12       Impact factor: 91.245

2.  A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.

Authors: 
Journal:  Cell       Date:  1993-03-26       Impact factor: 41.582

3.  A polymorphic DNA marker genetically linked to Huntington's disease.

Authors:  J F Gusella; N S Wexler; P M Conneally; S L Naylor; M A Anderson; R E Tanzi; P C Watkins; K Ottina; M R Wallace; A Y Sakaguchi
Journal:  Nature       Date:  1983 Nov 17-23       Impact factor: 49.962

4.  Ethical issues policy statement on Huntington's disease molecular genetics predictive test. International Huntington Association. World Federation of Neurology.

Authors:  L Went
Journal:  J Med Genet       Date:  1990-01       Impact factor: 6.318

5.  The psychological consequences of predictive testing for Huntington's disease. Canadian Collaborative Study of Predictive Testing.

Authors:  S Wiggins; P Whyte; M Huggins; S Adam; J Theilmann; M Bloch; S B Sheps; M T Schechter; M R Hayden
Journal:  N Engl J Med       Date:  1992-11-12       Impact factor: 91.245

6.  Predictive testing for Huntington disease in Canada: adverse effects and unexpected results in those receiving a decreased risk.

Authors:  M Huggins; M Bloch; S Wiggins; S Adam; O Suchowersky; M Trew; M Klimek; C R Greenberg; M Eleff; L P Thompson
Journal:  Am J Med Genet       Date:  1992-02-15

7.  Predictive testing for Huntington disease in Canada: the experience of those receiving an increased risk.

Authors:  M Bloch; S Adam; S Wiggins; M Huggins; M R Hayden
Journal:  Am J Med Genet       Date:  1992-02-15

8.  Predictive testing for Huntington's disease: protocol of the UK Huntington's Prediction Consortium.

Authors:  D Craufurd; A Tyler
Journal:  J Med Genet       Date:  1992-12       Impact factor: 6.318

9.  Presymptomatic diagnosis of delayed-onset disease with linked DNA markers. The experience in Huntington's disease.

Authors:  J Brandt; K A Quaid; S E Folstein; P Garber; N E Maestri; M H Abbott; P R Slavney; M L Franz; L Kasch; H H Kazazian
Journal:  JAMA       Date:  1989-06-02       Impact factor: 56.272

10.  Presymptomatic testing for huntington diseases: Recommendations for counseling.

Authors:  K A Quaid
Journal:  J Genet Couns       Date:  1992-12       Impact factor: 2.537

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  4 in total

1.  Huntington disease: a case study describing the complexities and nuances of predictive testing of monozygotic twins.

Authors:  Audrey Heimler; Andrea Zanko
Journal:  J Genet Couns       Date:  1995-06       Impact factor: 2.537

2.  Letters to the editor.

Authors:  A Heimler; S E Hodge
Journal:  J Genet Couns       Date:  1996-06       Impact factor: 2.537

3.  Genetic counseling for the next 25 years: Models for the future.

Authors:  R H Kenen; A C Smith
Journal:  J Genet Couns       Date:  1995-06       Impact factor: 2.537

4.  Defining the Critical Components of Informed Consent for Genetic Testing.

Authors:  Kelly E Ormond; Maia J Borensztein; Miranda L G Hallquist; Adam H Buchanan; William Andrew Faucett; Holly L Peay; Maureen E Smith; Eric P Tricou; Wendy R Uhlmann; Karen E Wain; Curtis R Coughlin
Journal:  J Pers Med       Date:  2021-12-05
  4 in total

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