Literature DB >> 24233712

Cancer. Potential of the synthetic lethality principle.

Sebastian M B Nijman1, Stephen H Friend.   

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Year:  2013        PMID： 24233712     DOI： 10.1126/science.1244669

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


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  31 in total

Review 1.  Functional genomics to uncover drug mechanism of action.

Authors:  Sebastian M B Nijman
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Review 2.  Small-molecule inhibitors of the Myc oncoprotein.

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3.  CRISPR/CAS9-based DNA damage response screens reveal gene-drug interactions.

Authors:  Dan Su; Xu Feng; Medina Colic; Yunfei Wang; Chunchao Zhang; Chao Wang; Mengfan Tang; Traver Hart; Junjie Chen
Journal:  DNA Repair (Amst)       Date:  2020-01-16

4.  Mitochondrial dysfunction induced by a SH2 domain-targeting STAT3 inhibitor leads to metabolic synthetic lethality in cancer cells.

Authors:  Davide Genini; Lara Brambilla; Erik Laurini; Jessica Merulla; Gianluca Civenni; Shusil Pandit; Rocco D'Antuono; Laurent Perez; David E Levy; Sabrina Pricl; Giuseppina M Carbone; Carlo V Catapano
Journal:  Proc Natl Acad Sci U S A       Date:  2017-06-05       Impact factor: 11.205

5.  Linking tumor mutations to drug responses via a quantitative chemical-genetic interaction map.

Authors:  Maria M Martins; Alicia Y Zhou; Alexandra Corella; Dai Horiuchi; Christina Yau; Taha Rakhshandehroo; John D Gordan; Rebecca S Levin; Jeff Johnson; John Jascur; Mike Shales; Antonio Sorrentino; Jaime Cheah; Paul A Clemons; Alykhan F Shamji; Stuart L Schreiber; Nevan J Krogan; Kevan M Shokat; Frank McCormick; Andrei Goga; Sourav Bandyopadhyay
Journal:  Cancer Discov       Date:  2014-12-12       Impact factor: 39.397

6.  HSP90 empowers evolution of resistance to hormonal therapy in human breast cancer models.

Authors:  Luke Whitesell; Sandro Santagata; Marc L Mendillo; Nancy U Lin; David A Proia; Susan Lindquist
Journal:  Proc Natl Acad Sci U S A       Date:  2014-12-08       Impact factor: 11.205

7.  A Network of Conserved Synthetic Lethal Interactions for Exploration of Precision Cancer Therapy.

Authors:  Rohith Srivas; John Paul Shen; Chih Cheng Yang; Su Ming Sun; Jianfeng Li; Andrew M Gross; James Jensen; Katherine Licon; Ana Bojorquez-Gomez; Kristin Klepper; Justin Huang; Daniel Pekin; Jia L Xu; Huwate Yeerna; Vignesh Sivaganesh; Leonie Kollenstart; Haico van Attikum; Pedro Aza-Blanc; Robert W Sobol; Trey Ideker
Journal:  Mol Cell       Date:  2016-07-21       Impact factor: 17.970

8.  Increased sensitivity to ionizing radiation by targeting the homologous recombination pathway in glioma initiating cells.

Authors:  Yi Chieh Lim; Tara L Roberts; Bryan W Day; Brett W Stringer; Sergei Kozlov; Shazrul Fazry; Zara C Bruce; Kathleen S Ensbey; David G Walker; Andrew W Boyd; Martin F Lavin
Journal:  Mol Oncol       Date:  2014-06-27       Impact factor: 6.603

Review 9.  Development of anticancer drugs based on the hallmarks of tumor cells.

Authors:  Natalia Bailón-Moscoso; Juan Carlos Romero-Benavides; Patricia Ostrosky-Wegman
Journal:  Tumour Biol       Date:  2014-01-29

Review 10.  Synthetic Lethal Networks for Precision Oncology: Promises and Pitfalls.

Authors:  John Paul Shen; Trey Ideker
Journal:  J Mol Biol       Date:  2018-06-20       Impact factor: 5.469
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