Literature DB >> 24222509

Contemplating genetic feedback regarding lung cancer susceptibility.

James A Shepperd1, Corinne A Novell, Suzanne C O'Neill, Sharron L Docherty, Saskia C Sanderson, Colleen M McBride, Isaac M Lipkus.   

Abstract

BACKGROUND AND
PURPOSE: We examined three theoretical models (self-enhancement theory, consistency theory, and a combined model) for understanding how expectations and test result favorability influence smokers' desire for a retest following hypothetical genetic test results.
METHOD: College smokers (N = 128) read a brochure describing a biomarker for lung cancer (the GSTM1 gene) then reported whether they thought they had the gene (indicating lower lung cancer risk) or were missing the gene (indicating higher lung cancer risk). Participants then reported whether they would get retested if they received favorable GSTM1 results versus unfavorable GSTM1 results.
RESULTS: Participants were most likely to want a retest, suggesting rejection of the results, if they expected favorable news yet received unfavorable news.
CONCLUSION: The findings supported the combined model such that smokers expressed greatest interest in a retest when they imagined genetic risk feedback that challenges both enhancement and consistency motives.

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Year:  2014        PMID: 24222509      PMCID: PMC4008648          DOI: 10.1007/s12160-013-9561-z

Source DB:  PubMed          Journal:  Ann Behav Med        ISSN: 0883-6612


  17 in total

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Authors:  Simone Benhamou; Won Jin Lee; Anna-Karin Alexandrie; Paolo Boffetta; Christine Bouchardy; Dorota Butkiewicz; Jurgen Brockmöller; Margie L Clapper; Ann Daly; Vita Dolzan; Jean Ford; Laura Gaspari; Aage Haugen; Ari Hirvonen; Kirsti Husgafvel-Pursiainen; Magnus Ingelman-Sundberg; Ivan Kalina; Masahiro Kihara; Pierre Kremers; Loïc Le Marchand; Stephanie J London; Valle Nazar-Stewart; Masako Onon-Kihara; Agneta Rannug; Marjorie Romkes; David Ryberg; Janeric Seidegard; Peter Shields; Richard C Strange; Isabelle Stücker; Jordi To-Figueras; Paul Brennan; Emanuela Taioli
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Review 4.  The behavioral response to personalized genetic information: will genetic risk profiles motivate individuals and families to choose more healthful behaviors?

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5.  Combined effect of GSTM1, GSTT1 and GSTP1 polymorphisms on histological subtypes of lung cancer.

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6.  Perceptions of Ashkenazi Jewish breast cancer patients on genetic testing for mutations in BRCA1 and BRCA2.

Authors:  K A Phillips; E Warner; W S Meschino; J Hunter; M Abdolell; G Glendon; I L Andrulis; P J Goodwin
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Review 10.  Effects of communicating DNA-based disease risk estimates on risk-reducing behaviours.

Authors:  Theresa M Marteau; David P French; Simon J Griffin; A T Prevost; Stephen Sutton; Clare Watkinson; Sophie Attwood; Gareth J Hollands
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2.  "I don't believe it." Acceptance and skepticism of genetic health information among African-American and White smokers.

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Journal:  Soc Sci Med       Date:  2017-05-03       Impact factor: 4.634

3.  In-vivo design feedback and perceived utility of a genetically-informed smoking risk tool among current smokers in the community.

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4.  Smokers' beliefs about the tobacco control potential of "a gene for smoking": a focus group study.

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  4 in total

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