Literature DB >> 241999

ATP, cyclic AMP, and magnesium increase the affinity of rat striatal tyrosine hydroxylase for its cofactor.

W Lovenberg, E A Bruckwick, I Hanbauer.   

Abstract

Treatment of rat striatal tyrosine hydroxylase [tyrosine 3-monooxygenase; L-tyrosine, tetrahydropteridine:oxygen oxidoreductase (3-hydroxylating); EC 1.14.16.2] with conditions optimal for protein phosphorylation results in the reduction of the tyrosine hydroxylase Km for the cofactor 6-methyltetrahydropterin from 0.50 mM to 0.16 mM. This reaction is dependent upon ATP, 3':5'-cAMP, and Mg++ and causes a marked decrease in the sensitivity to end-product inhibition. Other brain regions and the adrenal gland show a similar response.

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Year:  1975        PMID： 241999      PMCID： PMC432897          DOI： 10.1073/pnas.72.8.2955

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  15 in total

1.  Regulatory properties of soluble and particulate rat brain tyrosine hydroxylase.

Authors:  R T Kuczenski; A J Mandell
Journal:  J Biol Chem       Date:  1972-05-25       Impact factor: 5.157

2.  Regional distribution of tyrosine hydroxylase in rat brain.

Authors:  T J Cicero; L G Sharpe; E Robins; S S Grote
Journal:  J Neurochem       Date:  1972-09       Impact factor: 5.372

3.  Antipsychotic drugs and dopamine-stimulated adenylate cyclase prepared from corpus striatum of rat brain.

Authors:  M Karobath; H Leitich
Journal:  Proc Natl Acad Sci U S A       Date:  1974-07       Impact factor: 11.205

4.  Further studies on catecholamine synthesis in the spontaneously hypertensive rat: catecholamine synthesis in the central nervous system.

Authors:  H Yamabe; W De Jong; W Lovenberg
Journal:  Eur J Pharmacol       Date:  1973-04       Impact factor: 4.432

5.  Short-term control of tyrosine hydroxylase.

Authors:  A Carlsson; W Kehr; M Lindqvist
Journal:  Adv Biochem Psychopharmacol       Date:  1974

6.  Regulation of catecholamine synthesis in the rat brain in vitro by cyclic AMP.

Authors:  J E Harris; V H Morgenroth; R H Roth; R J Baldessarini
Journal:  Nature       Date:  1974-11-08       Impact factor: 49.962

7.  Changes of kinetic constant of striatal tyrosine hydroxylase elicited by neuroleptics that impair the function of dopamine receptors.

Authors:  B Zivkovic; A Guidotti
Journal:  Brain Res       Date:  1974-10-25       Impact factor: 3.252

Review 8.  Short- and long-term regulation of tyrosine hydroxylase.

Authors:  E Costa; A Guidotti; B Zivkovic
Journal:  Adv Biochem Psychopharmacol       Date:  1974

9.  Dopamine-sensitive adenylate cyclase in mammalian brain: a possible site of action of antipsychotic drugs.

Authors:  Y C Clement-Cormier; J W Kebabian; G L Petzold; P Greengard
Journal:  Proc Natl Acad Sci U S A       Date:  1974-04       Impact factor: 11.205

10.  Biosynthesis of tyrosine hydroxylase in rat adrenal medulla after exposure to cold.

Authors:  D M Chuang; E Costa
Journal:  Proc Natl Acad Sci U S A       Date:  1974-11       Impact factor: 11.205
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  17 in total

1.  Activation of striatal tyrosine hydroxylase by neurocatin, a neuroregulator from mammalian brain.

Authors:  A Pastuszko; P Pastuszko; D F Wilson
Journal:  Neurochem Res       Date:  1992-07       Impact factor: 3.996

2.  Direct phosphorylation of brain tyrosine hydroxylase by cyclic AMP-dependent protein kinase: mechanism of enzyme activation.

Authors:  T H Joh; D H Park; D J Reis
Journal:  Proc Natl Acad Sci U S A       Date:  1978-10       Impact factor: 11.205

Review 3.  A molecular description of nerve terminal function.

Authors:  L F Reichardt; R B Kelly
Journal:  Annu Rev Biochem       Date:  1983       Impact factor: 23.643

Review 4.  Complex molecular regulation of tyrosine hydroxylase.

Authors:  Izel Tekin; Robert Roskoski; Nurgul Carkaci-Salli; Kent E Vrana
Journal:  J Neural Transm (Vienna)       Date:  2014-05-28       Impact factor: 3.575

5.  Modification of the tyrosine hydroxylase assay. Increased enzyme activity in the presence of ascorbic acid.

Authors:  P Lerner; P Nosé; M M Ames; W Lovenberg
Journal:  Neurochem Res       Date:  1978-10       Impact factor: 3.996

6.  Acute effects of aspartame on systolic blood pressure in spontaneously hypertensive rats.

Authors:  P J Kiritsy; T J Maher
Journal:  J Neural Transm       Date:  1986       Impact factor: 3.575

7.  Identification by hydrogen/deuterium exchange of structural changes in tyrosine hydroxylase associated with regulation.

Authors:  Shanzhi Wang; Giri R Sura; Lawrence J Dangott; Paul F Fitzpatrick
Journal:  Biochemistry       Date:  2009-06-09       Impact factor: 3.162

Review 8.  Tyrosine hydroxylase regulation in the central nervous system.

Authors:  J M Masserano; N Weiner
Journal:  Mol Cell Biochem       Date:  1983       Impact factor: 3.396

9.  Evidence for the involvement of a cyclic AMP-independent protein kinase in the activation of soluble tyrosine hydroxylase from rat striatum.

Authors:  D W Andrews; T A Langan; N Weiner
Journal:  Proc Natl Acad Sci U S A       Date:  1983-04       Impact factor: 11.205

10.  Tyrosine's vasoactive effect in the dog shock model depends on the animal's starting blood pressure.

Authors:  L A Conlay; T J Maher; P L Moses; R J Wurtman
Journal:  J Neural Transm       Date:  1983       Impact factor: 3.575
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