Literature DB >> 24193723

Improving the quality of statistics in regulatory ecotoxicity tests.

P F Chapman1, M Crane, J Wiles, F Noppert, E McIndoe.   

Abstract

: The results of an international workshop on the use of statistics in regulatory ecotoxicology are presented. There are currently many errors of omission in the recommendations on statistical analysis given in test guidelines. These are identified and advice is given on how to incorporate best statistical practice. The use of the no observed effect concentration (NOEC) as a summary statistic is questioned, and an alternative is suggested. Several areas of research that would resolve uncertainty in the design and analysis of ecotoxicity tests are also identified.

Year:  1996        PMID: 24193723     DOI: 10.1007/BF00116338

Source DB:  PubMed          Journal:  Ecotoxicology        ISSN: 0963-9292            Impact factor:   2.823


  6 in total

1.  Efficient design for estimation of median lethal dose and quantal dose-response curves.

Authors:  L A Kalish
Journal:  Biometrics       Date:  1990-09       Impact factor: 2.571

2.  Statistical properties of the NOAEL.

Authors:  W Leisenring; L Ryan
Journal:  Regul Toxicol Pharmacol       Date:  1992-04       Impact factor: 3.271

3.  Time-to-event analyses of ecotoxicity data.

Authors:  M C Newman; J T McCloskey
Journal:  Ecotoxicology       Date:  1996-06       Impact factor: 2.823

4.  Choice of number of doses for maximum likelihood estimation of the ED50 for quantal dose-response data.

Authors:  H G Müller; T Schmitt
Journal:  Biometrics       Date:  1990-03       Impact factor: 2.571

5.  Interval estimation of the median lethal dose.

Authors:  D A Williams
Journal:  Biometrics       Date:  1986-09       Impact factor: 2.571

6.  A new method for determining allowable daily intakes.

Authors:  K S Crump
Journal:  Fundam Appl Toxicol       Date:  1984-10
  6 in total
  4 in total

1.  Data ranges in aquatic toxicity of chemicals: Consequences for environmental risk analysis.

Authors:  G Koller; K Hungerbühler; K Fent
Journal:  Environ Sci Pollut Res Int       Date:  2000       Impact factor: 4.223

2.  A study of the effects of chromium exposure on the growth of Pseudokirchneriella subcapitata (Korshikov) hindak evaluated by Central Composite Design and Response Surface Methodology.

Authors:  Patrícia C Giloni-Lima; Danieli Delello; Marcelo L M Cremonez; Márcia N Eler; Vanderlei A Lima; Evaldo L G Espíndola
Journal:  Ecotoxicology       Date:  2010-04-03       Impact factor: 2.823

3.  Recommendations for the design of laboratory studies on non-target arthropods for risk assessment of genetically engineered plants.

Authors:  Jörg Romeis; Richard L Hellmich; Marco P Candolfi; Keri Carstens; Adinda De Schrijver; Angharad M R Gatehouse; Rod A Herman; Joseph E Huesing; Morven A McLean; Alan Raybould; Anthony M Shelton; Annabel Waggoner
Journal:  Transgenic Res       Date:  2010-10-13       Impact factor: 2.788

Review 4.  Frontiers in quantifying wildlife behavioural responses to chemical pollution.

Authors:  Michael G Bertram; Jake M Martin; Erin S McCallum; Lesley A Alton; Jack A Brand; Bryan W Brooks; Daniel Cerveny; Jerker Fick; Alex T Ford; Gustav Hellström; Marcus Michelangeli; Shinichi Nakagawa; Giovanni Polverino; Minna Saaristo; Andrew Sih; Hung Tan; Charles R Tyler; Bob B M Wong; Tomas Brodin
Journal:  Biol Rev Camb Philos Soc       Date:  2022-03-01
  4 in total

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