OBJECTIVES: To review the proposed mechanisms of cognitive changes associated with non-central nervous system cancers and cancer treatment. DATA SOURCES: Review and synthesis of databased publications and review articles. CONCLUSION: Proposed mechanisms include cytokine upregulation, hormonal changes, neurotransmitter dysregulation, attentional fatigue, genetic predisposition, and comorbid symptoms. IMPLICATIONS FOR NURSING PRACTICE: Oncology nurses need to understand the multiple mechanisms that may contribute to the development of cancer- and treatment-related cognitive changes so that they can identify patients at high risk and help patients understand why these changes occur.
OBJECTIVES: To review the proposed mechanisms of cognitive changes associated with non-central nervous system cancers and cancer treatment. DATA SOURCES: Review and synthesis of databased publications and review articles. CONCLUSION: Proposed mechanisms include cytokine upregulation, hormonal changes, neurotransmitter dysregulation, attentional fatigue, genetic predisposition, and comorbid symptoms. IMPLICATIONS FOR NURSING PRACTICE: Oncology nurses need to understand the multiple mechanisms that may contribute to the development of cancer- and treatment-related cognitive changes so that they can identify patients at high risk and help patients understand why these changes occur.
Authors: Giuseppe Blasi; Venkata S Mattay; Alessandro Bertolino; Brita Elvevåg; Joseph H Callicott; Saumitra Das; Bhaskar S Kolachana; Michael F Egan; Terry E Goldberg; Daniel R Weinberger Journal: J Neurosci Date: 2005-05-18 Impact factor: 6.167
Authors: Ahmad R Hariri; Venkata S Mattay; Alessandro Tessitore; Bhaskar Kolachana; Francesco Fera; David Goldman; Michael F Egan; Daniel R Weinberger Journal: Science Date: 2002-07-19 Impact factor: 47.728
Authors: Catherine M Bender; John D Merriman; Amanda L Gentry; Gretchen M Ahrendt; Sarah L Berga; Adam M Brufsky; Frances E Casillo; Meredith M Dailey; Kirk I Erickson; Frances M Kratofil; Priscilla F McAuliffe; Margaret Q Rosenzweig; Christopher M Ryan; Susan M Sereika Journal: Cancer Date: 2015-04-23 Impact factor: 6.860
Authors: Joseph M Gullett; Ronald A Cohen; Gee Su Yang; Victoria S Menzies; Robert A Fieo; Debra L Kelly; Angela R Starkweather; Colleen K Jackson-Cook; Debra E Lyon Journal: Psychooncology Date: 2019-03-14 Impact factor: 3.894
Authors: Jennifer R Klemp; Jamie S Myers; Carol J Fabian; Bruce F Kimler; Qamar J Khan; Susan M Sereika; Annette L Stanton Journal: Support Care Cancer Date: 2017-08-28 Impact factor: 3.603
Authors: Juliet Shih; Heather Leutwyler; Christine Ritchie; Steven M Paul; Jon D Levine; Bruce Cooper; Fay Wright; Yvette P Conley; Christine Miaskowski Journal: Support Care Cancer Date: 2016-10-20 Impact factor: 3.603
Authors: Melissa Mazor; Janine K Cataldo; Kathryn Lee; Anand Dhruva; Bruce Cooper; Steven M Paul; Kimberly Topp; Betty J Smoot; Laura B Dunn; Jon D Levine; Yvette P Conley; Christine Miaskowski Journal: Eur J Oncol Nurs Date: 2017-12-19 Impact factor: 2.398
Authors: Inger Utne; Borghild Løyland; Ellen Karine Grov; Steven Paul; Melisa L Wong; Yvette P Conley; Bruce A Cooper; Jon D Levine; Christine Miaskowski Journal: Eur J Oncol Nurs Date: 2019-07-02 Impact factor: 2.398
Authors: Charlene J Treanor; Una C McMenamin; Roisin F O'Neill; Chris R Cardwell; Mike J Clarke; Marie Cantwell; Michael Donnelly Journal: Cochrane Database Syst Rev Date: 2016-08-16