Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Clinical neurogenetics: stroke.

Literature DB >> 24176416

Clinical neurogenetics: stroke.

Abstract

Understanding the genetic architecture of cerebrovascular disease holds promise of novel stroke prevention strategies and therapeutics that are both safe and effective. Apart from a few single-gene disorders associated with cerebral ischemia or intracerebral hemorrhage, stroke is a complex genetic phenotype that requires careful ascertainment and robust association testing for discovery and validation analyses. The recently uncovered shared genetic contribution between clinically manifest stroke syndromes and closely related intermediate cerebrovascular phenotypes offers effective and efficient approaches to complex trait analysis.

Entities: Chemical Disease Gene Mutation Species

Keywords: Cerebrovascular disease; Genetics; Genome-wide association study; Intracerebral hemorrhage; Ischemic stroke; Phenotype; Stroke subtype; White matter hyperintensity

Mesh：

Year: 2013 PMID： 24176416 PMCID： PMC3815700 DOI： 10.1016/j.ncl.2013.05.001

Source DB: PubMed Journal: Neurol Clin ISSN： 0733-8619 Impact factor: 3.806

101 in total

1. Recombinant tissue-type plasminogen activator use for ischemic stroke in the United States: a doubling of treatment rates over the course of 5 years.

Authors: Opeolu Adeoye; Richard Hornung; Pooja Khatri; Dawn Kleindorfer
Journal: Stroke Date: 2011-06-02 Impact factor: 7.914

2. Risk models for progression to advanced age-related macular degeneration using demographic, environmental, genetic, and ocular factors.

Authors: Johanna M Seddon; Robyn Reynolds; Yi Yu; Mark J Daly; Bernard Rosner
Journal: Ophthalmology Date: 2011-09-29 Impact factor: 12.079

Review 3. Genome-wide association studies for common diseases and complex traits.

Authors: Joel N Hirschhorn; Mark J Daly
Journal: Nat Rev Genet Date: 2005-02 Impact factor: 53.242

4. Many hypotheses but no replication for the association between PDE4D and stroke.

Authors: Jonathan Rosand; Nick Bayley; Natalia Rost; Paul I W de Bakker
Journal: Nat Genet Date: 2006-10 Impact factor: 38.330

5. Evidence for genetic variance in white matter hyperintensity volume in normal elderly male twins.

Authors: D Carmelli; C DeCarli; G E Swan; L M Jack; T Reed; P A Wolf; B L Miller
Journal: Stroke Date: 1998-06 Impact factor: 7.914

6. NINJ2 polymorphism is associated with ischemic stroke in Chinese Han population.

Authors: Xin-hong Wan; Shu-juan Li; Ping Cheng; Qi Zhang; Xin-chun Yang; Guang-zhen Zhong; Wen-li Hu; Li Jin; Xiao-feng Wang
Journal: J Neurol Sci Date: 2011-06-30 Impact factor: 3.181

7. Burden of risk alleles for hypertension increases risk of intracerebral hemorrhage.

Authors: Guido J Falcone; Alessandro Biffi; William J Devan; Jeremiasz M Jagiella; Helena Schmidt; Brett Kissela; Björn M Hansen; Jordi Jimenez-Conde; Eva Giralt-Steinhauer; Roberto Elosua; Elisa Cuadrado-Godia; Carolina Soriano; Alison M Ayres; Kristin Schwab; Joanna Pera; Andrzej Urbanik; Natalia S Rost; Joshua N Goldstein; Anand Viswanathan; Alexander Pichler; Christian Enzinger; Bo Norrving; David L Tirschwell; Magdy Selim; Devin L Brown; Scott L Silliman; Bradford B Worrall; James F Meschia; Chelsea S Kidwell; Joan Montaner; Israel Fernandez-Cadenas; Pilar Delgado; Joseph P Broderick; Steven M Greenberg; Jaume Roquer; Arne Lindgren; Agnieszka Slowik; Reinhold Schmidt; Matthew L Flaherty; Dawn O Kleindorfer; Carl D Langefeld; Daniel Woo; Jonathan Rosand
Journal: Stroke Date: 2012-08-28 Impact factor: 7.914

8. White matter hyperintensity volume is increased in small vessel stroke subtypes.

Authors: N S Rost; R M Rahman; A Biffi; E E Smith; A Kanakis; K Fitzpatrick; F Lima; B B Worrall; J F Meschia; R D Brown; T G Brott; A G Sorensen; S M Greenberg; K L Furie; J Rosand
Journal: Neurology Date: 2010-11-09 Impact factor: 9.910

9. Genetic variation in white matter hyperintensity volume in the Framingham Study.

Authors: Larry D Atwood; Philip A Wolf; Nancy L Heard-Costa; Joseph M Massaro; Alexa Beiser; Ralph B D'Agostino; Charles DeCarli
Journal: Stroke Date: 2004-05-13 Impact factor: 7.914

10. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment.

Authors: H P Adams; B H Bendixen; L J Kappelle; J Biller; B B Love; D L Gordon; E E Marsh
Journal: Stroke Date: 1993-01 Impact factor: 7.914

1 in total

1. Genetic Predisposition to Severe COVID-19 Might Increase the Risk of Stroke: A Two-Sample Mendelian Randomization Study.

Authors: Jinji Zhang; Fayong Wu; Shenge Chen; Ying Zhu; Xian Luo; Xiaolin Qiu
Journal: Front Genet Date: 2022-08-12 Impact factor: 4.772

1 in total