PURPOSE: To estimate specific organ and effective doses to patients resulting from the (18)F-FDG ((18)F-2-deoxy-D-glucose) and (18)F-FDOPA (6-fluoro-((18)F)-L-3, 4-dihydroxyphenylalanine) PET/CT examinations for whole body and brain. MATERIALS AND METHODS: Three protocols for whole body and three for brain PET/CT were used. The CTDI values were measured using standard head and body CT phantoms and also computed using a software CT-Expo for dose evaluation from the CT component. OLINDA software based on MIRD method was used for estimating doses from the PET component of the PET/CT examination. RESULTS: The organ doses from (18)F-FDG and (18)F-FDOPA whole body and brain PET/CT studies were estimated. The total effective dose from a typical protocol of whole body PET/CT examination was 14.4 mSv for females and 11.8 mSv for male patients from (18)F-FDG, whereas it was 11 mSv for female and 9.1 mSv for male patients from (18)F-FDOPA. The total effective doses from a typical protocol for PET/CT studies of brain was 6.5 mSv for females and 5.1 mSv for males from (18)F-FDG whereas it was 3.7 mSv for females and 2.8 mSv for males from (18)F-FDOPA. CONCLUSIONS: The effective radiation doses from whole body PET/CT examination was approximately 4-8 times higher than the background radiation dose from both (18)F-FDG and (18)F-FDOPA scans, while it was 1-3 times the background radiation dose from PET/CT scans of brain.
PURPOSE: To estimate specific organ and effective doses to patients resulting from the (18)F-FDG ((18)F-2-deoxy-D-glucose) and (18)F-FDOPA (6-fluoro-((18)F)-L-3, 4-dihydroxyphenylalanine) PET/CT examinations for whole body and brain. MATERIALS AND METHODS: Three protocols for whole body and three for brain PET/CT were used. The CTDI values were measured using standard head and body CT phantoms and also computed using a software CT-Expo for dose evaluation from the CT component. OLINDA software based on MIRD method was used for estimating doses from the PET component of the PET/CT examination. RESULTS: The organ doses from (18)F-FDG and (18)F-FDOPA whole body and brain PET/CT studies were estimated. The total effective dose from a typical protocol of whole body PET/CT examination was 14.4 mSv for females and 11.8 mSv for male patients from (18)F-FDG, whereas it was 11 mSv for female and 9.1 mSv for male patients from (18)F-FDOPA. The total effective doses from a typical protocol for PET/CT studies of brain was 6.5 mSv for females and 5.1 mSv for males from (18)F-FDG whereas it was 3.7 mSv for females and 2.8 mSv for males from (18)F-FDOPA. CONCLUSIONS: The effective radiation doses from whole body PET/CT examination was approximately 4-8 times higher than the background radiation dose from both (18)F-FDG and (18)F-FDOPA scans, while it was 1-3 times the background radiation dose from PET/CT scans of brain.
Authors: Farida Aimi Mustapha; Farahnaz Ahmad Anwar Bashah; Ihsan M Yassin; Ahmad Saad Fathinul Fikri; Abdul Jalil Nordin; Hairil Rashmizal Abdul Razak Journal: Quant Imaging Med Surg Date: 2017-06
Authors: Aruna Kaushik; Abhinav Jaimini; Madhavi Tripathi; Maria D'Souza; Rajnish Sharma; Anupam Mondal; Anil K Mishra; Bilikere S Dwarakanath Journal: Indian J Med Res Date: 2015-12 Impact factor: 2.375
Authors: Josep M Martí-Climent; Elena Prieto; Verónica Morán; Lidia Sancho; Macarena Rodríguez-Fraile; Javier Arbizu; María J García-Velloso; José A Richter Journal: EJNMMI Res Date: 2017-04-24 Impact factor: 3.138
Authors: Isaac M Jackson; So Jeong Lee; Alexandra R Sowa; Melissa E Rodnick; Laura Bruton; Mara Clark; Sean Preshlock; Jill Rothley; Virginia E Rogers; Leslie E Botti; Bradford D Henderson; Brian G Hockley; Jovany Torres; David M Raffel; Allen F Brooks; Kirk A Frey; Michael R Kilbourn; Robert A Koeppe; Xia Shao; Peter J H Scott Journal: EJNMMI Radiopharm Chem Date: 2020-11-11