Literature DB >> 28774479

Gender Differences in the Association between Adverse Childhood Experiences and Cancer.

Héctor E Alcalá1, A Janet Tomiyama2, Ondine S von Ehrenstein3.   

Abstract

OBJECTIVES: Adverse childhood experiences (ACEs) have been linked to a variety of diseases in adulthood, including cancer. However, current research has yet to determine if all abuse types are associated with cancer and if women are more adversely impacted by ACEs than men.
METHODS: Data from the 2011 Behavioral Risk Factor Surveillance System, a national survey of American adults 18 and older (N = 111,964) were analyzed. Logistic regression models were fit to estimate odds of ever being diagnosed with cancer after experiencing one or more of eight different ACEs, while adjusting for potential confounders. These analyses were then stratified by gender.
RESULTS: Among women, childhood experiences of physical abuse, sexual abuse, emotional abuse, living with someone who was mentally ill, living with a problem drinker, living with a drug user, and living in a household where adults treated each other violently were associated with higher odds of cancer. Among men, only emotional abuse was associated with higher odds of cancer.
CONCLUSIONS: Results suggest that ACEs increase risk of cancer later in life. However, this impact occurs mostly among women. This finding may be because women experience many ACEs at higher rates than men and because women, via sexual abuse, can be exposed to cancer-causing viruses.
Copyright © 2017 Jacobs Institute of Women's Health. Published by Elsevier Inc. All rights reserved.

Entities:  

Mesh:

Year:  2017        PMID: 28774479      PMCID: PMC5694368          DOI: 10.1016/j.whi.2017.06.002

Source DB:  PubMed          Journal:  Womens Health Issues        ISSN: 1049-3867


  43 in total

1.  Exposure to childhood sexual and physical abuse and subsequent educational achievement outcomes.

Authors:  Joseph M Boden; L John Horwood; David M Fergusson
Journal:  Child Abuse Negl       Date:  2007-11-08

Review 2.  The embodiment of adverse childhood experiences and cancer development: potential biological mechanisms and pathways across the life course.

Authors:  Michelle Kelly-Irving; Laurence Mabile; Pascale Grosclaude; Thierry Lang; Cyrille Delpierre
Journal:  Int J Public Health       Date:  2012-05-16       Impact factor: 3.380

3.  Examination of the Factorial Structure of Adverse Childhood Experiences and Recommendations for Three Subscale Scores.

Authors:  Derek C Ford; Melissa T Merrick; Sharyn E Parks; Matthew J Breiding; Leah K Gilbert; Valerie J Edwards; Satvinder S Dhingra; John P Barile; William W Thompson
Journal:  Psychol Violence       Date:  2014-10

4.  Colorectal cancer screening and adverse childhood experiences: Which adversities matter?

Authors:  Héctor E Alcalá; Jessica Keim-Malpass; Emma Mitchell
Journal:  Child Abuse Negl       Date:  2017-05-02

5.  Does childhood misfortune increase cancer risk in adulthood?

Authors:  Patricia M Morton; Markus H Schafer; Kenneth F Ferraro
Journal:  J Aging Health       Date:  2012-07-04

Review 6.  Sexually transmitted infections in children as a marker of child sexual abuse and direction of future research.

Authors:  Karen E Rogstad; Dawn Wilkinson; Angela Robinson
Journal:  Curr Opin Infect Dis       Date:  2016-02       Impact factor: 4.915

7.  A revised inventory of Adverse Childhood Experiences.

Authors:  David Finkelhor; Anne Shattuck; Heather Turner; Sherry Hamby
Journal:  Child Abuse Negl       Date:  2015-08-07

8.  Adverse Childhood Experiences and Health in Adulthood in a Rural Population-Based Sample.

Authors:  Kristen C Iniguez; Rachel V Stankowski
Journal:  Clin Med Res       Date:  2016-08-08

9.  Violence against Women Raises Risk of Cervical Cancer.

Authors:  Ann L Coker; Claudia Hopenhayn; Christopher P DeSimone; Heather M Bush; Leslie Crofford
Journal:  J Womens Health (Larchmt)       Date:  2009-08       Impact factor: 2.681

10.  Associations of child sexual and physical abuse with obesity and depression in middle-aged women.

Authors:  Paul Rohde; Laura Ichikawa; Gregory E Simon; Evette J Ludman; Jennifer A Linde; Robert W Jeffery; Belinda H Operskalski
Journal:  Child Abuse Negl       Date:  2008-10-22
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  5 in total

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Authors:  Maeve Wallace; Erica Felker-Kantor; Aubrey Madkour; Tekeda Ferguson; David Welsh; Patricia Molina; Katherine P Theall
Journal:  AIDS Behav       Date:  2020-06

2.  Adverse Childhood Experiences and Subjective Cognitive Decline in the US.

Authors:  Monique J Brown; Amandeep Kaur; Titilayo James; Carlos Avalos; Prince N O Addo; Elizabeth Crouch; Nikki L Hill
Journal:  J Appl Gerontol       Date:  2021-12-13

3.  Risk and Protective Factors Related to Early Adverse Life Events in Irritable Bowel Syndrome.

Authors:  Tiffany Ju; Bruce D Naliboff; Wendy Shih; Angela P Presson; Cathy Liu; Arpana Gupta; Emeran A Mayer; Lin Chang
Journal:  J Clin Gastroenterol       Date:  2020-01       Impact factor: 3.174

4.  The Long-Term Health and Human Capital Consequences of Adverse Childhood Experiences in the Birth to Thirty Cohort: Single, Cumulative, and Clustered Adversity.

Authors:  Sara N Naicker; Marilyn N Ahun; Sahba Besharati; Shane A Norris; Massimiliano Orri; Linda M Richter
Journal:  Int J Environ Res Public Health       Date:  2022-02-05       Impact factor: 3.390

5.  Childhood psychosocial stress is linked with impaired vascular endothelial function, lower SIRT1, and oxidative stress in young adulthood.

Authors:  Nathaniel D M Jenkins; Emily M Rogers; Nile F Banks; Patrick M Tomko; Christina M Sciarrillo; Sam R Emerson; Ashlee Taylor; T Kent Teague
Journal:  Am J Physiol Heart Circ Physiol       Date:  2021-07-30       Impact factor: 5.125

  5 in total

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