Literature DB >> 20092967

Childhood trauma and dissociation in patients with alcohol dependence, drug dependence, or both-A multi-center study.

Ingo Schäfer1, Willemien Langeland, Johanna Hissbach, Christel Luedecke, Martin D Ohlmeier, Claudia Chodzinski, Ulrich Kemper, Peter Keiper, Dirk Wedekind, Ursula Havemann-Reinecke, Sybille Teunissen, Steffen Weirich, Martin Driessen.   

Abstract

BACKGROUND: The aims of this study were to examine the level of dissociative symptoms in patients with different substance related disorders (alcohol dependence, drug dependence, and combined alcohol and drug dependence), and to investigate the influence of potentially traumatic events in childhood, age, gender, and posttraumatic stress disorder on the relationship between dissociative symptoms and type of substance abuse.
METHODS: Of the 459 participants (59.7% male) 182 (39.7%) were alcohol-dependent (A), 154 (33.6%) were drug-dependent (D), and 123 (26.8%) were dependent on both, alcohol and drugs (AD) based on the DSM-IV criteria for a current diagnosis. Participants completed the Childhood Trauma Questionnaire (CTQ) and the Dissociative Experiences Scale (DES). The International Diagnostics Checklist (IDCL) was administered to diagnose PTSD.
RESULTS: Higher levels of dissociation were observed in patients with drug dependence as compared to patients with mere alcohol dependence (mean DES group A: 9.9+/-8.8; group D: 12.9+/-11.7; group AD: 15.1+/-11.3). However, when severity of potentially traumatic events in childhood, PTSD, age and gender were included in the analysis, the influence of the type of substance abuse did not prove to be statistically significant. The variable most strongly related to dissociative symptoms was severity of potentially traumatic events in childhood, in particular emotional abuse, even after controlling for PTSD and other potential confounders.
CONCLUSIONS: It seems appropriate to screen SUD patients for dissociative symptoms, especially those with a more complex risk profile including (additional) drug abuse, female gender, younger age and most importantly a history of childhood trauma. Copyright (c) 2009 Elsevier Ireland Ltd. All rights reserved.

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Year:  2010        PMID: 20092967     DOI: 10.1016/j.drugalcdep.2009.12.012

Source DB:  PubMed          Journal:  Drug Alcohol Depend        ISSN: 0376-8716            Impact factor:   4.492


  15 in total

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2.  Dissociation, PTSD, and substance abuse: an empirical study.

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4.  Childhood maltreatment profile in a clinical population in China: a further analysis with existing data of an epidemiologic survey.

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10.  Effects of methamphetamine abuse and serotonin transporter gene variants on aggression and emotion-processing neurocircuitry.

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