| Literature DB >> 24119568 |
Tanja Schneider1, Anna Müller2, Henrike Miess3, Harald Gross4.
Abstract
Cyclic lipopeptides (CLPs) are a promising class of natural products with antibiotic properties. CLPs are amphiphilic molecules, composed of a fatty acid tail linked to a short oligopeptide which form a macrocylic ring structure. This review presents an overview of this class of antibiotics, focusing on the current and potential therapeutic applications and placing particular emphasis on the molecular modes of action of these compounds.Entities:
Keywords: Antibiotics; Cyclic lipopeptides; Daptomycin; Mode of action; Polymyxin
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Year: 2013 PMID: 24119568 DOI: 10.1016/j.ijmm.2013.08.009
Source DB: PubMed Journal: Int J Med Microbiol ISSN: 1438-4221 Impact factor: 3.473