| Literature DB >> 24117650 |
Michael K Gibson1, Arashinder S Dhaliwal1, Nicholas J Clemons2,3,4, Wayne A Phillips2,3,4, Katerina Dvorak5, Daniel Tong6, Simon Law6, E Daniel Pirchi7, Jari Räsänen8, Mark J Krasna9, Kaushal Parikh10, Kausilia K Krishnadath10, Yu Chen11, Leonard Griffiths11, Benjamin J Colleypriest11, J Mark Farrant11, David Tosh11, Kiron M Das12, Manisha Bajpai12.
Abstract
The following paper on the molecular biology of Barrett's esophagus (BE) includes commentaries on signaling pathways central to the development of BE including Hh, NF-κB, and IL-6/STAT3; surgical approaches for esophagectomy and classification of lesions by appropriate therapy; the debate over the merits of minimally invasive esophagectomy versus open surgery; outcomes for patients with pharyngolaryngoesophagectomy; the applications of neoadjuvant chemotherapy and chemoradiotherapy; animal models examining the surgical models of BE and esophageal adenocarcinoma; the roles of various morphogens and Cdx2 in BE; and the use of in vitro BE models for chemoprevention studies.Entities:
Keywords: Barrett's esophagus; MIE; esophageal adenocarcinoma; esophagectomy
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Year: 2013 PMID： 24117650 DOI： 10.1111/nyas.12252
Source DB: PubMed Journal: Ann N Y Acad Sci ISSN： 0077-8923 Impact factor: 5.691