Literature DB >> 24112310

Barrow-in-Furness: a large community legionellosis outbreak in the UK.

E Bennett1, M Ashton2, N Calvert3, J Chaloner4, J Cheesbrough5, J Egan1, I Farrell6, I Hall1, T G Harrison7, F C Naik8, S Partridge9, Q Syed10, R N Gent1.   

Abstract

A community outbreak of legionellosis occurred in Barrow-in-Furness, Cumbria, during July and August 2002. A descriptive study and active case-finding were instigated and all known wet cooling systems and other potential sources were investigated. Genotypic and phenotypic analysis, and amplified fragment length polymorphism of clinical human and environmental isolates confirmed the air-conditioning unit of a council-owned arts and leisure centre to be the source of infection. Subsequent sequence-based typing confirmed this link. One hundred and seventy-nine cases, including seven deaths [case fatality rate (CFR) 3·9%] were attributed to the outbreak. Timely recognition and management of the incident very likely led to the low CFR compared to other outbreaks. The outbreak highlights the responsibility associated with managing an aerosol-producing system, with the potential to expose and infect a large proportion of the local population and the consequent legal ramifications and human cost.

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Year:  2013        PMID: 24112310      PMCID: PMC9151204          DOI: 10.1017/S0950268813002483

Source DB:  PubMed          Journal:  Epidemiol Infect        ISSN: 0950-2688            Impact factor:   4.434


  29 in total

1.  The Barrow-in-Furness legionnaires' outbreak: qualitative study of the hospital response and the role of the major incident plan.

Authors:  A F Smith; C Wild; J Law
Journal:  Emerg Med J       Date:  2005-04       Impact factor: 2.740

2.  The legionnaires' outbreak in Barrow-in-Furness, summer 2002.

Authors:  David Telford; Sue Partridge; Ian Cumming; Andrew Smith; Nigel Calvert
Journal:  J Epidemiol Community Health       Date:  2006-06       Impact factor: 3.710

3.  Addition of neuA, the gene encoding N-acylneuraminate cytidylyl transferase, increases the discriminatory ability of the consensus sequence-based scheme for typing Legionella pneumophila serogroup 1 strains.

Authors:  Sandra Ratzow; Valeria Gaia; Jürgen Herbert Helbig; Norman K Fry; Paul Christian Lück
Journal:  J Clin Microbiol       Date:  2007-04-04       Impact factor: 5.948

4.  A large Legionnaires' disease outbreak in Pamplona, Spain: early detection, rapid control and no case fatality.

Authors:  J Castilla; A Barricarte; J Aldaz; M García Cenoz; T Ferrer; C Pelaz; S Pineda; B Baladrón; I Martín; B Goñi; P Aratajo; J Chamorro; F Lameiro; L Torroba; I Dorronsoro; V Martínez-Artola; M J Esparza; M A Gastaminza; P Fraile; P Aldaz
Journal:  Epidemiol Infect       Date:  2007-07-30       Impact factor: 2.451

5.  The effect of a large Legionnaires' disease outbreak in Southwest Edinburgh on acute and critical care services.

Authors:  J F Irons; M J G Dunn; K Kefala; S Thorn; F Lakha; D Caesar; D D Cameron; D McCormick; A McCallum; K O Helgason; I F Laurenson; R L Paterson; A Greening; M Fried; A T Hill; M Hanson; M A Gillies
Journal:  QJM       Date:  2013-08-22

6.  Modeling Legionnaires' disease outbreaks: estimating the timing of an aerosolized release using symptom-onset dates.

Authors:  Joseph R Egan; Ian M Hall; David J Lemon; Steve Leach
Journal:  Epidemiology       Date:  2011-03       Impact factor: 4.822

7.  A community outbreak of Legionnaires' disease: evidence of a cooling tower as the source.

Authors:  M Sabria; J Alvarez; A Dominguez; A Pedrol; G Sauca; L Salleras; A Lopez; M A Garcia-Nuñez; I Parron; M P Barrufet
Journal:  Clin Microbiol Infect       Date:  2006-07       Impact factor: 8.067

8.  Molecular epidemiology of an outbreak of Legionnaires' disease associated with a cooling tower in Genova-Sestri Ponente, Italy.

Authors:  M Castellani Pastoris; L Ciceroni; R Lo Monaco; P Goldoni; B Mentore; G Flego; L Cattani; S Ciarrocchi; A Pinto; P Visca
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1997-12       Impact factor: 3.267

9.  An outbreak of Legionnaires' disease at the Melbourne Aquarium, April 2000: investigation and case-control studies.

Authors:  Jane E Greig; John A Carnie; Graham F Tallis; Norbert J Ryan; Agnes G Tan; Ian R Gordon; Bernard Zwolak; Jennie A Leydon; Charles S Guest; William G Hart
Journal:  Med J Aust       Date:  2004-06-07       Impact factor: 7.738

10.  An outbreak of Legionnaire's disease among visitors to a fair in Belgium in 1999.

Authors:  K De Schrijver; K Dirven; K Van Bouwel; L Mortelmans; P Van Rossom; T De Beukelaar; C Vael; M Fajo; O Ronveaux; M F Peeters; A Van der Zee; A Bergmans; M Ieven; H Goossens
Journal:  Public Health       Date:  2003-03       Impact factor: 2.427

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  9 in total

Review 1.  A review of back-calculation techniques and their potential to inform mitigation strategies with application to non-transmissible acute infectious diseases.

Authors:  Joseph R Egan; Ian M Hall
Journal:  J R Soc Interface       Date:  2015-05-06       Impact factor: 4.118

2.  Regulating Cooling Towers to Prevent Outbreaks of Legionnaires' Disease.

Authors:  Mary T Bassett; Sharon Balter
Journal:  Public Health Rep       Date:  2017-02-01       Impact factor: 2.792

3.  Whole-Genome Mapping as a Novel High-Resolution Typing Tool for Legionella pneumophila.

Authors:  Thijs Bosch; Sjoerd M Euser; Fabian Landman; Jacob P Bruin; Ed P IJzerman; Jeroen W den Boer; Leo M Schouls
Journal:  J Clin Microbiol       Date:  2015-07-22       Impact factor: 5.948

4.  Legionella longbeachae detected in an industrial cooling tower linked to a legionellosis outbreak, New Zealand, 2015; possible waterborne transmission?

Authors:  C N Thornley; D J Harte; R P Weir; L J Allen; K J Knightbridge; P R T Wood
Journal:  Epidemiol Infect       Date:  2017-06-19       Impact factor: 4.434

5.  Legionnaires' Disease Outbreaks and Cooling Towers, New York City, New York, USA.

Authors:  Robert Fitzhenry; Don Weiss; Dan Cimini; Sharon Balter; Christopher Boyd; Lisa Alleyne; Renee Stewart; Natasha McIntosh; Andrea Econome; Ying Lin; Inessa Rubinstein; Teresa Passaretti; Anna Kidney; Pascal Lapierre; Daniel Kass; Jay K Varma
Journal:  Emerg Infect Dis       Date:  2017-11       Impact factor: 6.883

6.  Dispersion of Legionella bacteria in atmosphere: A practical source location estimation method.

Authors:  Steven Dyke; Iain Barrass; Kevin Pollock; Ian M Hall
Journal:  PLoS One       Date:  2019-11-25       Impact factor: 3.240

7.  Opportunistic Premise Plumbing Pathogens. A Potential Health Risk in Water Mist Systems Used as a Cooling Intervention.

Authors:  Edmore Masaka; Sue Reed; Maggie Davidson; Jacques Oosthuizen
Journal:  Pathogens       Date:  2021-04-12

Review 8.  Outbreaks of Legionnaires' Disease and Pontiac Fever 2006-2017.

Authors:  K A Hamilton; A J Prussin; W Ahmed; C N Haas
Journal:  Curr Environ Health Rep       Date:  2018-06

9.  Strategies for controlling non-transmissible infection outbreaks using a large human movement data set.

Authors:  Penelope A Hancock; Yasmin Rehman; Ian M Hall; Obaghe Edeghere; Leon Danon; Thomas A House; Matthew J Keeling
Journal:  PLoS Comput Biol       Date:  2014-09-11       Impact factor: 4.475

  9 in total

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