OBJECTIVE: Evaluate the association of a small third-trimester abdominal circumference (AC < 10th percentile) in the setting of a normal estimated fetal weight (EFW ≥ 10th percentile) with gestational age at delivery, indication for delivery and neonatal outcomes. METHODS: Retrospective cohort study at an academic hospital of women with singleton pregnancy seen for ultrasound from 28+0-33+6 weeks of gestation during 2009-2011. Outcomes were compared between two groups: normal AC (AC and EFW ≥ 10th percentile) and small AC (AC < 10th percentile and EFW ≥ 10th percentile). RESULTS: Among 592 pregnancies, fetuses in the small AC group (n = 55) experienced a higher incidence of overall preterm delivery (RR: 2.2, 95% CI: 1.3-3.7) and provider-initiated preterm delivery (RR: 3.7, CI: 1.8-7.5) compared to those in the normal AC group (n = 537). Neonates in the small AC group had a lower median birth weight whether delivered at term (p < 0.001) or preterm (p = 0.04), but were not more likely to experience intensive care unit admission or respiratory distress syndrome (all p ≥ 0.35). CONCLUSIONS: Small AC, even in the setting of an EFW ≥ 10th percentile, was associated with a higher incidence of overall and provider-initiated preterm delivery despite similar neonatal outcomes. Further investigation is warranted to determine whether these preterm deliveries could be prevented.
OBJECTIVE: Evaluate the association of a small third-trimester abdominal circumference (AC < 10th percentile) in the setting of a normal estimated fetal weight (EFW ≥ 10th percentile) with gestational age at delivery, indication for delivery and neonatal outcomes. METHODS: Retrospective cohort study at an academic hospital of women with singleton pregnancy seen for ultrasound from 28+0-33+6 weeks of gestation during 2009-2011. Outcomes were compared between two groups: normal AC (AC and EFW ≥ 10th percentile) and small AC (AC < 10th percentile and EFW ≥ 10th percentile). RESULTS: Among 592 pregnancies, fetuses in the small AC group (n = 55) experienced a higher incidence of overall preterm delivery (RR: 2.2, 95% CI: 1.3-3.7) and provider-initiated preterm delivery (RR: 3.7, CI: 1.8-7.5) compared to those in the normal AC group (n = 537). Neonates in the small AC group had a lower median birth weight whether delivered at term (p < 0.001) or preterm (p = 0.04), but were not more likely to experience intensive care unit admission or respiratory distress syndrome (all p ≥ 0.35). CONCLUSIONS: Small AC, even in the setting of an EFW ≥ 10th percentile, was associated with a higher incidence of overall and provider-initiated preterm delivery despite similar neonatal outcomes. Further investigation is warranted to determine whether these preterm deliveries could be prevented.
Authors: Robert L Goldenberg; Michael G Gravett; Jay Iams; Aris T Papageorghiou; Sarah A Waller; Michael Kramer; Jennifer Culhane; Fernando Barros; Augustin Conde-Agudelo; Zulfiqar A Bhutta; Hannah E Knight; Jose Villar Journal: Am J Obstet Gynecol Date: 2011-10-25 Impact factor: 8.661
Authors: M Tanvig; S Wehberg; C A Vinter; J S Joergensen; P G Ovesen; H Beck-Nielsen; D M Jensen; H T Christesen Journal: BJOG Date: 2012-11-12 Impact factor: 6.531
Authors: Adi L Tarca; Roberto Romero; Dereje W Gudicha; Offer Erez; Edgar Hernandez-Andrade; Lami Yeo; Gaurav Bhatti; Percy Pacora; Eli Maymon; Sonia S Hassan Journal: Am J Obstet Gynecol Date: 2018-02 Impact factor: 8.661