Literature DB >> 24095199

Erythro-myeloid progenitors: "definitive" hematopoiesis in the conceptus prior to the emergence of hematopoietic stem cells.

Jenna M Frame1, Kathleen E McGrath, James Palis.   

Abstract

Erythro-myeloid progenitors (EMP) serve as a major source of hematopoiesis in the developing conceptus prior to the formation of a permanent blood system. In this review, we summarize the current knowledge regarding the emergence, fate, and potential of this hematopoietic stem cell (HSC)-independent wave of hematopoietic progenitors, focusing on the murine embryo as a model system. A better understanding of the temporal and spatial control of hematopoietic emergence in the embryo will ultimately improve our ability to derive hematopoietic stem and progenitor cells from embryonic stem cells and induced pluripotent stem cells to serve therapeutic purposes.
© 2013.

Entities:  

Keywords:  AGM; BFU-E; E; EMP; ESC; Embryogenesis; Erythro-myeloid progenitors; HSC; Hematopoiesis; Hpf; Yolk sac; aorta–gonad-mesonephros; burst-forming units erythroid; embryonic day; embryonic stem cell; erythro-myeloid progenitors; hematopoietic stem cell; hours post fertilization; iPSC; induced pluripotent stem cell

Mesh:

Year:  2013        PMID: 24095199      PMCID: PMC3852668          DOI: 10.1016/j.bcmd.2013.09.006

Source DB:  PubMed          Journal:  Blood Cells Mol Dis        ISSN: 1079-9796            Impact factor:   3.039


  113 in total

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Journal:  Cell       Date:  1996-09-20       Impact factor: 41.582

2.  Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis.

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Journal:  Proc Natl Acad Sci U S A       Date:  1996-04-16       Impact factor: 11.205

3.  First appearance, distribution, and origin of macrophages in the early development of the avian central nervous system.

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Journal:  J Comp Neurol       Date:  1993-04-01       Impact factor: 3.215

4.  Scavenger macrophages and central macrophages of erythroblastic islands in liver hemopoiesis of the fetal and early postnatal mouse: a semithin light- and electron-microscopic study.

Authors:  K Sasaki; H Iwatsuki; M Suda; C Itano
Journal:  Acta Anat (Basel)       Date:  1993

5.  The oncogenic cysteine-rich LIM domain protein rbtn2 is essential for erythroid development.

Authors:  A J Warren; W H Colledge; M B Carlton; M J Evans; A J Smith; T H Rabbitts
Journal:  Cell       Date:  1994-07-15       Impact factor: 41.582

6.  Hematopoietic commitment during embryonic stem cell differentiation in culture.

Authors:  G Keller; M Kennedy; T Papayannopoulou; M V Wiles
Journal:  Mol Cell Biol       Date:  1993-01       Impact factor: 4.272

7.  Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL.

Authors:  R A Shivdasani; E L Mayer; S H Orkin
Journal:  Nature       Date:  1995-02-02       Impact factor: 49.962

8.  AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis.

Authors:  T Okuda; J van Deursen; S W Hiebert; G Grosveld; J R Downing
Journal:  Cell       Date:  1996-01-26       Impact factor: 41.582

9.  Development of hematopoietic stem cell activity in the mouse embryo.

Authors:  A M Müller; A Medvinsky; J Strouboulis; F Grosveld; E Dzierzak
Journal:  Immunity       Date:  1994-07       Impact factor: 31.745

10.  Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene.

Authors:  L Robb; I Lyons; R Li; L Hartley; F Köntgen; R P Harvey; D Metcalf; C G Begley
Journal:  Proc Natl Acad Sci U S A       Date:  1995-07-18       Impact factor: 11.205

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  65 in total

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5.  C-Myb(+) erythro-myeloid progenitor-derived fetal monocytes give rise to adult tissue-resident macrophages.

Authors:  Guillaume Hoeffel; Jinmiao Chen; Yonit Lavin; Donovan Low; Francisca F Almeida; Peter See; Anna E Beaudin; Josephine Lum; Ivy Low; E Camilla Forsberg; Michael Poidinger; Francesca Zolezzi; Anis Larbi; Lai Guan Ng; Jerry K Y Chan; Melanie Greter; Burkhard Becher; Igor M Samokhvalov; Miriam Merad; Florent Ginhoux
Journal:  Immunity       Date:  2015-04-21       Impact factor: 31.745

Review 6.  The Regulatory Role of IFN-γ on the Proliferation and Differentiation of Hematopoietic Stem and Progenitor Cells.

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Review 7.  Modeling Leukemia with Human Induced Pluripotent Stem Cells.

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10.  Ontogeny of Tumor-associated Macrophages and Its Implication in Cancer Regulation.

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