Literature DB >> 2407845

The polymerase chain reaction: current and future clinical applications.

J R Lynch1, J M Brown.   

Abstract

The polymerase chain reaction has undergone rapid improvement since its initial development, such that the technique currently permits rapid, accurate, predictive tests to be made in the field of prenatal diagnosis and has greatly aided forensic medicine. It is anticipated that the polymerase chain reaction will also facilitate advances in other fields, in particular preimplantation diagnosis, virology, bacteriology, and cancer therapy.

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Mesh：

Year:  1990        PMID： 2407845      PMCID： PMC1016870          DOI： 10.1136/jmg.27.1.2

Source DB:  PubMed          Journal:  J Med Genet        ISSN： 0022-2593            Impact factor:   6.318


  42 in total

1.  Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia.

Authors:  R K Saiki; S Scharf; F Faloona; K B Mullis; G T Horn; H A Erlich; N Arnheim
Journal:  Science       Date:  1985-12-20       Impact factor: 47.728

2.  Applied molecular genetics: new tools for microbiologists and clinicians.

Authors:  B I Eisenstein; N C Engleberg
Journal:  J Infect Dis       Date:  1986-03       Impact factor: 5.226

3.  Direct cloning and sequence analysis of enzymatically amplified genomic sequences.

Authors:  S J Scharf; G T Horn; H A Erlich
Journal:  Science       Date:  1986-09-05       Impact factor: 47.728

4.  Analysis of enzymatically amplified beta-globin and HLA-DQ alpha DNA with allele-specific oligonucleotide probes.

Authors:  R K Saiki; T L Bugawan; G T Horn; K B Mullis; H A Erlich
Journal:  Nature       Date:  1986 Nov 13-19       Impact factor: 49.962

5.  Prevalence of ras gene mutations in human colorectal cancers.

Authors:  J L Bos; E R Fearon; S R Hamilton; M Verlaan-de Vries; J H van Boom; A J van der Eb; B Vogelstein
Journal:  Nature       Date:  1987 May 28-Jun 3       Impact factor: 49.962

6.  Hypervariable 'minisatellite' regions in human DNA.

Authors:  A J Jeffreys; V Wilson; S L Thein
Journal:  Nature       Date:  1985 Mar 7-13       Impact factor: 49.962

7.  Direct detection of haemoglobin E with synthetic oligonucleotides.

Authors:  S L Thein; J R Lynch; D J Weatherall; R B Wallace
Journal:  Lancet       Date:  1986-01-11       Impact factor: 79.321

Review 8.  The molecular genetics of human hemoglobin.

Authors:  F S Collins; S M Weissman
Journal:  Prog Nucleic Acid Res Mol Biol       Date:  1984

9.  Detection of minimal residual cells carrying the t(14;18) by DNA sequence amplification.

Authors:  M S Lee; K S Chang; F Cabanillas; E J Freireich; J M Trujillo; S A Stass
Journal:  Science       Date:  1987-07-10       Impact factor: 47.728

10.  Characterization of c-Ki-ras oncogene alleles by direct sequencing of enzymatically amplified DNA from carcinogen-induced tumors.

Authors:  G McMahon; E Davis; G N Wogan
Journal:  Proc Natl Acad Sci U S A       Date:  1987-07       Impact factor: 11.205
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  3 in total

1.  Molecular biology: the forensic applications.

Authors:  M A Bolster; J Walker; A M Pollock; J Street; C T Doyle
Journal:  Ir J Med Sci       Date:  1994-07       Impact factor: 1.568

2.  Mutation analysis in Turkish phenylketonuria patients.

Authors:  M Ozgüç; I Ozalp; T Coşkun; E Yilmaz; H Erdem; S Ayter
Journal:  J Med Genet       Date:  1993-02       Impact factor: 6.318

Review 3.  The Medicinal Chemistry of Artificial Nucleic Acids and Therapeutic Oligonucleotides.

Authors:  Miklós Bege; Anikó Borbás
Journal:  Pharmaceuticals (Basel)       Date:  2022-07-22
  3 in total

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