Literature DB >> 24063388

Estimation of radiation exposure for brain perfusion CT: standard protocol compared with deviations in protocol.

Jenny K Hoang1, Chu Wang, Donald P Frush, David S Enterline, Ehsan Samei, Greta Toncheva, Carolyn Lowry, Terry T Yoshizumi.   

Abstract

OBJECTIVE: The purpose of this study was to measure the organ doses and estimate the effective dose for the standard brain perfusion CT protocol and erroneous protocols.
MATERIALS AND METHODS: An anthropomorphic phantom with metal oxide semiconductor field effect transistor (MOSFET) detectors was scanned on a 64-MDCT scanner. Protocol 1 used a standard brain perfusion protocol with 80 kVp and fixed tube current of 200 mA. Protocol 2 used 120 kVp and fixed tube current of 200 mA. Protocol 3 used 120 kVp with automatic tube current modulation (noise index, 2.4; minimum, 100 mA; maximum, 520 mA).
RESULTS: Compared with protocol 1, the effective dose was 2.8 times higher with protocol 2 and 7.8 times higher with protocol 3. For all protocols, the peak dose was highest in the skin, followed by the brain and calvarial marrow. Compared with protocol 1, the peak skin dose was 2.6 times higher with protocol 2 and 6.7 times higher with protocol 3. The peak skin dose for protocol 3 exceeded 3 Gy. The ocular lens received significant scatter radiation: 177 mGy for protocol 2 and 435 mGy for protocol 3, which were 4.6 and 11.3 times the dose for protocol 1, respectively.
CONCLUSION: Compared with the standard protocol, erroneous protocols of increasing the tube potential from 80 kVp to 120 kVp will lead to a three- to fivefold increase in organ doses, and concurrent use of high peak kilovoltage with incorrectly programmed tube current modulation can increase dose to organs by 7- to 11-fold. Tube current modulation with a low noise index can lead to doses to the skin and ocular lens that are close to thresholds for tissue reactions.

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Year:  2013        PMID: 24063388     DOI: 10.2214/AJR.12.10031

Source DB:  PubMed          Journal:  AJR Am J Roentgenol        ISSN: 0361-803X            Impact factor:   3.959


  10 in total

1.  Low-Dose Volume-Perfusion CT of the Brain: Effects of Radiation Dose Reduction on Performance of Perfusion CT Algorithms.

Authors:  A E Othman; S Afat; C Brockmann; O Nikoubashman; G Bier; M A Brockmann; K Nikolaou; J H Tai; Z P Yang; J H Kim; M Wiesmann
Journal:  Clin Neuroradiol       Date:  2015-12-15       Impact factor: 3.649

2.  Image quality, radiation dose and diagnostic accuracy of 70 kVp whole brain volumetric CT perfusion imaging: a preliminary study.

Authors:  Xiao Kun Fang; Qian Qian Ni; U Joseph Schoepf; Chang Sheng Zhou; Guo Zhong Chen; Song Luo; Stephen R Fuller; Carlo N De Cecco; Long Jiang Zhang; Guang Ming Lu
Journal:  Eur Radiol       Date:  2016-02-06       Impact factor: 5.315

3.  Reduced-dose CT protocol for the assessment of cerebral vasospasm.

Authors:  N Bricout; L Estrade; F Boustia; E Kalsoum; J P Pruvo; X Leclerc
Journal:  Neuroradiology       Date:  2015-08-28       Impact factor: 2.804

4.  Improvement of image quality and radiation dose of CT perfusion of the brain by means of low-tube voltage (70 KV).

Authors:  Zhen-lin Li; Hang Li; Kai Zhang; Wang-jiang Li; Xian Chen; Bin Wu; Bin Song
Journal:  Eur Radiol       Date:  2014-06-04       Impact factor: 5.315

5.  Cerebral perfusion and compensatory blood supply in patients with recent small subcortical infarcts.

Authors:  Salvatore Rudilosso; Carlos Laredo; Marco Mancosu; Nuria Moya-Planas; Yashu Zhao; Oscar Chirife; Ángel Chamorro; Xabier Urra
Journal:  J Cereb Blood Flow Metab       Date:  2018-02-13       Impact factor: 6.200

6.  Measured Head CT/CTA Skin Dose and Intensive Care Unit Patient Cumulative Exposure.

Authors:  R D Nawfel; G S Young
Journal:  AJNR Am J Neuroradiol       Date:  2017-01-19       Impact factor: 3.825

7.  Dynamic CTA-Derived Perfusion Maps Predict Final Infarct Volume: The Simple Perfusion Reconstruction Algorithm.

Authors:  C C McDougall; L Chan; S Sachan; J Guo; R G Sah; B K Menon; A M Demchuk; M D Hill; N D Forkert; C D d'Esterre; P A Barber
Journal:  AJNR Am J Neuroradiol       Date:  2020-10-01       Impact factor: 3.825

Review 8.  Mechanical Thrombectomy in Pregnancy: Report of 2 Cases and Review of the Literature.

Authors:  Pervinder Bhogal; Marta Aguilar; Muhammad AlMatter; Ulrich Karck; Hansjörg Bäzner; Hans Henkes
Journal:  Interv Neurol       Date:  2017-01-19

9.  Validation of a method for estimating peak skin dose from CT-guided procedures.

Authors:  A Kyle Jones; Meghan E Kisiel; X John Rong; Alda L Tam
Journal:  J Appl Clin Med Phys       Date:  2021-05-06       Impact factor: 2.102

10.  A Novel Singular Value Decomposition-Based Denoising Method in 4-Dimensional Computed Tomography of the Brain in Stroke Patients with Statistical Evaluation.

Authors:  Wonseok Yang; Jun-Yong Hong; Jeong-Youn Kim; Seung-Ho Paik; Seung Hyun Lee; Ji-Su Park; Gihyoun Lee; Beop Min Kim; Young-Jin Jung
Journal:  Sensors (Basel)       Date:  2020-05-28       Impact factor: 3.576

  10 in total

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