Literature DB >> 2404938

Identification of BlaR, the signal transducer for beta-lactamase production in Bacillus licheniformis, as a penicillin-binding protein with strong homology to the OXA-2 beta-lactamase (class D) of Salmonella typhimurium.

Y F Zhu1, I H Curran, B Joris, J M Ghuysen, J O Lampen.   

Abstract

The blaR gene of Bacillus licheniformis encodes the signal transducer for induction of the class A beta-lactamase. The protein product, BlaR, has a hydrophilic carboxy region that binds beta-lactams and shows high sequence homology to the class D beta-lactamases, particularly the OXA-2 beta-lactamase of Salmonella typhimurium. The BlaR-beta-lactam complex is stable and may provide the continuing stimulus needed for the prolonged production of the enzyme.

Entities:  

Mesh：

Substances：

Year:  1990        PMID： 2404938      PMCID： PMC208548          DOI： 10.1128/jb.172.2.1137-1141.1990

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  18 in total

1.  Precise insertion of antibiotic resistance determinants into Tn21-like transposons: nucleotide sequence of the OXA-1 beta-lactamase gene.

Authors:  M Ouellette; L Bissonnette; P H Roy
Journal:  Proc Natl Acad Sci U S A       Date:  1987-11       Impact factor: 11.205

2.  Transcriptional analysis of beta-lactamase regulation in Bacillus licheniformis.

Authors:  A J Salerno; J O Lampen
Journal:  J Bacteriol       Date:  1986-06       Impact factor: 3.490

3.  Sequence of PSE-2 beta-lactamase.

Authors:  P Huovinen; S Huovinen; G A Jacoby
Journal:  Antimicrob Agents Chemother       Date:  1988-01       Impact factor: 5.191

4.  ampC cephalosporinase of Escherichia coli K-12 has a different evolutionary origin from that of beta-lactamases of the penicillinase type.

Authors:  B Jaurin; T Grundström
Journal:  Proc Natl Acad Sci U S A       Date:  1981-08       Impact factor: 11.205

5.  Pattern recognition in nucleic acid sequences. I. A general method for finding local homologies and symmetries.

Authors:  W B Goad; M I Kanehisa
Journal:  Nucleic Acids Res       Date:  1982-01-11       Impact factor: 16.971

6.  Nucleotide sequence of the gene encoding the Streptomyces albus G beta-lactamase precursor.

Authors:  P Dehottay; J Dusart; F De Meester; B Joris; J Van Beeumen; T Erpicum; J M Frère; J M Ghuysen
Journal:  Eur J Biochem       Date:  1987-07-15

7.  A second regulatory gene, blaR1, encoding a potential penicillin-binding protein required for induction of beta-lactamase in Bacillus licheniformis.

Authors:  T Kobayashi; Y F Zhu; N J Nicholls; J O Lampen
Journal:  J Bacteriol       Date:  1987-09       Impact factor: 3.490

8.  A bacteriophage T7 RNA polymerase/promoter system for controlled exclusive expression of specific genes.

Authors:  S Tabor; C C Richardson
Journal:  Proc Natl Acad Sci U S A       Date:  1985-02       Impact factor: 11.205

9.  The crystal structure of the beta-lactamase of Streptomyces albus G at 0.3 nm resolution.

Authors:  O Dideberg; P Charlier; J P Wéry; P Dehottay; J Dusart; T Erpicum; J M Frère; J M Ghuysen
Journal:  Biochem J       Date:  1987-08-01       Impact factor: 3.857

10.  Penicillinase from Bacillus licheniformis: nucleotide sequence of the gene and implications for the biosynthesis of a secretory protein in a Gram-positive bacterium.

Authors:  K Neugebauer; R Sprengel; H Schaller
Journal:  Nucleic Acids Res       Date:  1981-06-11       Impact factor: 16.971
View more
  22 in total

1.  Structure, function, and fate of the BlaR signal transducer involved in induction of beta-lactamase in Bacillus licheniformis.

Authors:  Y Zhu; S Englebert; B Joris; J M Ghuysen; T Kobayashi; J O Lampen
Journal:  J Bacteriol       Date:  1992-10       Impact factor: 3.490

2.  Induction of a Streptomyces cacaoi beta-lactamase gene cloned in S. lividans.

Authors:  V M Lenzini; J Magdalena; C Fraipont; B Joris; A Matagne; J Dusart
Journal:  Mol Gen Genet       Date:  1992-10

3.  Nucleotide sequence of beta-lactamase regulatory genes from staphylococcal plasmid pI258.

Authors:  P Z Wang; S J Projan; R P Novick
Journal:  Nucleic Acids Res       Date:  1991-07-25       Impact factor: 16.971

4.  The Enterococcus hirae R40 penicillin-binding protein 5 and the methicillin-resistant Staphylococcus aureus penicillin-binding protein 2' are similar.

Authors:  A el Kharroubi; P Jacques; G Piras; J Van Beeumen; J Coyette; J M Ghuysen
Journal:  Biochem J       Date:  1991-12-01       Impact factor: 3.857

5.  Regulation and Anaerobic Function of the Clostridioides difficile β-Lactamase.

Authors:  Brindar K Sandhu; Adrianne N Edwards; Sarah E Anderson; Emily C Woods; Shonna M McBride
Journal:  Antimicrob Agents Chemother       Date:  2019-12-20       Impact factor: 5.191

6.  Analysis of diversity of mutations in the mecI gene and mecA promoter/operator region of methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis.

Authors:  N Kobayashi; K Taniguchi; S Urasawa
Journal:  Antimicrob Agents Chemother       Date:  1998-03       Impact factor: 5.191

7.  Site-saturation mutagenesis of position V117 in OXA-1 β-lactamase: effect of side chain polarity on enzyme carboxylation and substrate turnover.

Authors:  Jennifer S Buchman; Kyle D Schneider; Aaron R Lloyd; Stephanie L Pavlish; David A Leonard
Journal:  Biochemistry       Date:  2012-03-28       Impact factor: 3.162

8.  Penicillin sulfone inhibitors of class D beta-lactamases.

Authors:  Sarah M Drawz; Christopher R Bethel; Venkata R Doppalapudi; Anjaneyulu Sheri; Sundar Ram Reddy Pagadala; Andrea M Hujer; Marion J Skalweit; Vernon E Anderson; Shu G Chen; John D Buynak; Robert A Bonomo
Journal:  Antimicrob Agents Chemother       Date:  2010-01-19       Impact factor: 5.191

9.  Isolation and sequence analysis of dacB, which encodes a sporulation-specific penicillin-binding protein in Bacillus subtilis.

Authors:  C E Buchanan; M L Ling
Journal:  J Bacteriol       Date:  1992-03       Impact factor: 3.490

10.  Genes involved in the regulation of beta-lactamase production in enterococci and staphylococci.

Authors:  K K Zscheck; B E Murray
Journal:  Antimicrob Agents Chemother       Date:  1993-09       Impact factor: 5.191
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.