Literature DB >> 24009793

Deconvolution estimation of mixture distributions with boundaries.

Mihee Lee1, Peter Hall, Haipeng Shen, J S Marron, Jon Tolle, Christina Burch.   

Abstract

In this paper, motivated by an important problem in evolutionary biology, we develop two sieve type estimators for distributions that are mixtures of a finite number of discrete atoms and continuous distributions under the framework of measurement error models. While there is a large literature on deconvolution problems, only two articles have previously addressed the problem taken up in our article, and they use relatively standard Fourier deconvolution. As a result the estimators suggested in those two articles are degraded seriously by boundary effects and negativity. A major contribution of our article is correct handling of boundary effects; our method is asymptotically unbiased at the boundaries, and also is guaranteed to be nonnegative. We use roughness penalization to improve the smoothness of the resulting estimator and reduce the estimation variance. We illustrate the performance of the proposed estimators via our real driving application in evolutionary biology and two simulation studies. Furthermore, we establish asymptotic properties of the proposed estimators.

Entities:  

Keywords:  Boundary effect; maximum likelihood; measurement error; mixture distribution; penalization; sieve method

Year:  2013        PMID: 24009793      PMCID: PMC3759521          DOI: 10.1214/13-EJS774

Source DB:  PubMed          Journal:  Electron J Stat        ISSN: 1935-7524            Impact factor:   1.125


  4 in total

1.  Experimental estimate of the abundance and effects of nearly neutral mutations in the RNA virus phi 6.

Authors:  Christina L Burch; Sebastien Guyader; Daniel Samarov; Haipeng Shen
Journal:  Genetics       Date:  2007-03-04       Impact factor: 4.562

2.  Exploring the information in p-values for the analysis and planning of multiple-test experiments.

Authors:  David Ruppert; Dan Nettleton; J T Gene Hwang
Journal:  Biometrics       Date:  2007-06       Impact factor: 2.571

3.  Deconvolution estimation of mixture distributions with boundaries.

Authors:  Mihee Lee; Peter Hall; Haipeng Shen; J S Marron; Jon Tolle; Christina Burch
Journal:  Electron J Stat       Date:  2013       Impact factor: 1.125

4.  Epistasis and its relationship to canalization in the RNA virus phi 6.

Authors:  Christina L Burch; Lin Chao
Journal:  Genetics       Date:  2004-06       Impact factor: 4.562

  4 in total
  1 in total

1.  Deconvolution estimation of mixture distributions with boundaries.

Authors:  Mihee Lee; Peter Hall; Haipeng Shen; J S Marron; Jon Tolle; Christina Burch
Journal:  Electron J Stat       Date:  2013       Impact factor: 1.125

  1 in total

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