Literature DB >> 24002219

[Current therapeutic options for Peyronie's disease].

A Hauptmann1, T Diemer, W Weidner.   

Abstract

Peyronie's disease is a heterogeneous disorder with typical symptoms of plaque formation, penile pain, deviation, penile shortening and erectile dysfunction. The etiology is unknown. Repetitive microtraumatic lesions with the formation of inelastic scar tissue at the level of the tunica albuginea are discussed as a trigger mechanism for a questionable genetic disposition. A non-surgical therapy based on a clear pathophysiology does not exist although several conservative treatment regimes are practiced. In the stable stage of the disease surgical therapy of penile angulation is the most frequent operation. Depending on the deviation angle, penile length and erectile dysfunction, different types of straightening surgery can be offered. This article provides an overview of conservative management and commonly used surgical techniques.

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Year:  2013        PMID: 24002219     DOI: 10.1007/s00120-013-3171-z

Source DB:  PubMed          Journal:  Urologe A        ISSN: 0340-2592            Impact factor:   0.639


  49 in total

1.  Treatment of Peyronie's disease with oral colchicine: long-term results and predictive parameters of successful outcome.

Authors:  A Kadioglu; A Tefekli; T Köksal; M Usta; H Erol
Journal:  Int J Impot Res       Date:  2000-06       Impact factor: 2.896

2.  The treatment of Peyronie's disease with tamoxifen.

Authors:  D J Ralph; M D Brooks; G F Bottazzo; J P Pryor
Journal:  Br J Urol       Date:  1992-12

3.  Treatment of Peyronie's disease with oral pentoxifylline.

Authors:  William O Brant; Robert C Dean; Tom F Lue
Journal:  Nat Clin Pract Urol       Date:  2006-02

4.  A new, innovative, lengthening surgical procedure for Peyronie's disease by penile prosthesis implantation with double dorsal-ventral patch graft: the "sliding technique".

Authors:  Luigi Rolle; Carlo Ceruti; Massimiliano Timpano; Omidreza Sedigh; Paolo Destefanis; Elisa Galletto; Marco Falcone; Dario Fontana
Journal:  J Sex Med       Date:  2012-03-16       Impact factor: 3.802

5.  The role of vacuum pump therapy to mechanically straighten the penis in Peyronie's disease.

Authors:  Amr Abdel Raheem; Giulio Garaffa; Tarek Abdel Raheem; Michelle Dixon; Amanda Kayes; Nim Christopher; David Ralph
Journal:  BJU Int       Date:  2010-10       Impact factor: 5.588

6.  Summary of the recommendations on sexual dysfunctions in men.

Authors:  Tom F Lue; François Giuliano; Francesco Montorsi; Raymond C Rosen; Karl-Erik Andersson; Stanley Althof; George Christ; Dimitrios Hatzichristou; Mark Hirsch; Yasasuke Kimoto; Ronald Lewis; Kevin McKenna; Chris MacMahon; Alvaro Morales; John Mulcahy; Harin Padma-Nathan; John Pryor; Inigo Saenz de Tejada; Ridwan Shabsigh; Gorm Wagner
Journal:  J Sex Med       Date:  2004-07       Impact factor: 3.802

Review 7.  Clinical efficacy, safety and tolerability of collagenase clostridium histolyticum for the treatment of peyronie disease in 2 large double-blind, randomized, placebo controlled phase 3 studies.

Authors:  Martin Gelbard; Irwin Goldstein; Wayne J G Hellstrom; Chris G McMahon; Ted Smith; James Tursi; Nigel Jones; Gregory J Kaufman; Culley C Carson
Journal:  J Urol       Date:  2013-01-31       Impact factor: 7.450

8.  Bother and distress associated with Peyronie's disease: validation of the Peyronie's disease questionnaire.

Authors:  Wayne J G Hellstrom; Robert Feldman; Raymond C Rosen; Ted Smith; Gregory Kaufman; James Tursi
Journal:  J Urol       Date:  2013-01-31       Impact factor: 7.450

9.  A double-blind placebo-controlled study of the efficacy and safety of pentoxifylline in early chronic Peyronie's disease.

Authors:  Mohammad Reza Safarinejad; Majid Ali Asgari; Seyyed Yousof Hosseini; Farid Dadkhah
Journal:  BJU Int       Date:  2009-10-26       Impact factor: 5.588

10.  Penile traction therapy for treatment of Peyronie's disease: a single-center pilot study.

Authors:  Laurence A Levine; Mark Newell; Frederick L Taylor
Journal:  J Sex Med       Date:  2008-03-26       Impact factor: 3.802

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